Faculty profile
Guangdong Yang
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Research
Latest papers
IRP1 deficiency promotes fibroblast activation through iron dysregulation: protective modulation by H2S.
Molecular and cellular biochemistry · 2026 · senior author
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Crosstalk Between H2S and Hormones: The Bilateral Relationship and Molecular Mechanisms.
Handbook of experimental pharmacology · 2026 · first author
Latest funding
- $120,000
Deciphering the roles of cystathionine gamma-lyase/H2S system in Fe-S protein biogenesis and iron homeostasis
NSERC · 2022 · Principal investigator
- $186,000
Dynamics and regulation of cysteine S-sulfhydration in cellular functions
NSERC · 2016 · Principal investigator
52 publications.
IRP1 deficiency promotes fibroblast activation through iron dysregulation: protective modulation by H2S.
Bola A, McFadden A, Ochigbo OF, Arif HM, Wang R, Pantopoulos K, Yang G
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
Zhang L, Zhang Y, Wen D, Guo S, Qi X, Wang H, Sun Y, Yang G, Wang Y, Xue S
Crosstalk Between H2S and Hormones: The Bilateral Relationship and Molecular Mechanisms.
Yang G
Brassinin Induces H2S Signals and Improves Vascular Smooth Muscle Cell Functions.
Fergani J, Han X, Jin Z, Pei Y, Montaut S, Yang G
Localized delivery and retention of hydrogen sulfide causing regional lipid accumulation in mouse adipose tissues in vivo.
Verma R, Fu M, Arif HM, Yang G, Sarkar I, Kaur K, Matson JB, Wu L, Wang R
H2S inhibition of xanthine dehydrogenase to xanthine oxidase conversion reduces uric acid levels and improves myoblast functions.
MacNeil J, Wang Y, Yang G
Tea Polyphenol-Derived Carbon Dots Alleviate Abdominal Aortic Aneurysm Progression by Mitigating Oxidative Stress and Ferroptosis.
Zhang L, Chen S, Ning M, Guo S, Wen D, Wang H, Sun Y, Yang G, Wang Y, Xue S
Cystathionine gamma-lyase deficiency exaggerates diethylnitrosamine-induced liver damage in mice.
Ligi S, Ali A, Yang G
H2S Protects from Rotenone-Induced Ferroptosis by Stabilizing Fe-S Clusters in Rat Cardiac Cells.
Linjacki S, Wang Y, Baath N, Mantle D, Yang G
H2S-mediated blockage of protein acetylation and oxidative stress attenuates lipid overload-induced cardiac senescence.
Yu R, Wang Y, Zhu J, Yang G
Deciphering the roles of cystathionine gamma-lyase/H2S system in Fe-S protein biogenesis and iron homeostasis
Principal investigators: Yang, Guangdong
Keywords: hydrogen sulfide; s-sulfhydration; cysteine; cystathionine gamma-lyase; fe-s clusters; ferroptosis; cysteine desulfurase; iron metabolism; iron regulatory protein; oxygen
Dynamics and regulation of cysteine S-sulfhydration in cellular functions
Principal investigators: Yang, Guangdong
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Rui Wang and Guangdong Yang: 6 shared papers
- Rui Wang and Lingyun Wu: 2 shared papers
- Guangdong Yang and Lingyun Wu: 2 shared papers
- Alp Sener and Guangdong Yang: 1 shared paper
- Guangdong Yang and Nelson Belzile: 1 shared paper
- Biology
- Department of Chemistry and Biochemistry
- Surgery
- Chemistry and Biochemistry
Co-authors at Laurentian University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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