Faculty profile

Sheldon Tobe

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Sheldon Tobe

Researcher

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
10 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 3 research grants (3 CIHR), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

1,143

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Adaptive Trials Biostatistics Clinical Trials Hqp Development Job Shadowing Mentorship Pedogagy Training

Latest papers

Consensus Methodology for the Canadian Brain and Heart Clinical Practice Guidelines
CJC Open · 2026
Appraising the Quality of Patient Decision Aids for Brain and Heart Health: An Environmental Scan with a Health Equity Lens.
CJC open · 2026
The Role of Renal Denervation in the Treatment of Hypertension in Canada: A Case-Based Discussion from the Canadian Hypertension Specialists Society.
American journal of hypertension · 2026

All 33 publications

Latest funding

Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)
CIHR · 2022 · Principal investigator
$4,314,242
Diabetes Connections - Shookaawaapinewin Mamow Wicihiwewin: Reorienting diabetes care in First Nations communities in Northwestern Ontario through empowerment, autonomy and ownership for health and wellbeing
CIHR · 2022 · Co-investigator
$2,000,000
Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)
CIHR · 2022 · Principal investigator
$1,078,562

All 7 grants and awards

33 publications.

Consensus Methodology for the Canadian Brain and Heart Clinical Practice Guidelines

Li Z, Tobe S, Sherifali D, Racey M, Hua-Stewart D, Gravel CA, Lewis M, Mehta S, Hill MD, Haider N

CJC Open20262 citations

DOI: 10.1016/j.cjco.2025.11.018

Appraising the Quality of Patient Decision Aids for Brain and Heart Health: An Environmental Scan with a Health Equity Lens.

Lewis KB, Goge S, Kiss A, Carley M, Julien AM, Higdon G, Fiedorowicz JG, Graham ID, Achim AM, Beanlands R, Gessese S, Straus S, Edwards J, Bujold M, Tobe S, Stacey D

CJC open2026

DOI: 10.1016/j.cjco.2026.03.012 PMID: 42483023

The Role of Renal Denervation in the Treatment of Hypertension in Canada: A Case-Based Discussion from the Canadian Hypertension Specialists Society.

Padwal RS, Dorsch M, Tobe S, Ringrose J, Schiffrin EL, Feldman RD, Prasad B, Leung AA, Dubrofsky L, Tran KC, Madan M, Machan L, Khan N

American journal of hypertension2026

DOI: 10.1093/ajh/hpaf236 PMID: 41351821

Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1

Rosende A, Romero C, DiPette DJ, Brettler J, Van der Stuyft P, Satheesh G, Perel P, Chapman N, Moran AE, Schutte AE

Global Heart202523 citations

DOI: 10.5334/gh.1428

Uptake of novel evidence-based therapies in patients with type 2 diabetes after a cardiovascular event: insights from CANHEART.

Thompson W, Wong B, Sivaswamy A, Ferreira-Legere L, Lee DS, Abdel-Qadir H, Ko DT, Weisman A, Tobe S, Jackevicius CA, Goodman SG, Farkouh ME, Udell JA

CJC open2025

DOI: 10.1016/j.cjco.2025.02.008 PMID: 40894837

Cost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Canada.

McFarlane PA, Madan M, Ryschon AM, Tobe S, Schiffrin EL, Padwal RS, Feldman R, Dresser G, Machan L, Sadri H, Cao KN, Pietzsch JB

Journal of medical economics2025

DOI: 10.1080/13696998.2024.2441072 PMID: 39660790

Patient Perspectives on a Pilot Virtual Follow-up Program After Hypertensive Disorders of Pregnancy: A Qualitative Study

Dubrofsky L, Gundy S, Boesch L, Poolman K, Nerenberg KA, Tobe S

CJC Open20238 citationsSenior author

DOI: 10.1016/j.cjco.2023.03.003

Association of prior outpatient diabetes screening with cardiovascular events and mortality among people with incident diabetes: a population-based cohort study.

Ke C, Chu A, Shah BR, Tobe S, Tu K, Fang J, Vaid H, Liu P, Cader A, Lee DS

Cardiovascular diabetology2023

DOI: 10.1186/s12933-023-01952-y PMID: 37641086

Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease.

Smeijer JD, Koomen JV, Kohan DE, McMurray JJV, Bakris GL, Correa-Rotter R, Hou FF, Kitzman DW, Makino H, Mayer G, Nowicki M, Perkovic V, Rossing P, Tobe S, Parving HH, de Zeeuw D, Heerspink HJL

Clinical pharmacology and therapeutics2022

DOI: 10.1002/cpt.2721 PMID: 35892316

Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident Heart Failure.

Smeijer JD, Koomen J, Kohan DE, McMurray JJV, Bakris GL, Correa-Rotter R, Hou FF, Januzzi JL, Kitzman DW, Kolansky DM, Makino H, Perkovic V, Tobe S, Parving HH, de Zeeuw D, Heerspink HJL

JACC. Heart failure2022

DOI: 10.1016/j.jchf.2022.03.004 PMID: 35772861

Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)

Principal investigatorCIHR2022Training Grant: Clinical Trials Training Platforms

Principal investigators: Cheung, Angela M; Ahmed, Sofia B; Allen, Upton D; Bhat, Mamatha; Boyd, Steven K; Crawley, Angela M; Dolatabadi, Elham; Fahim, Christine; Farkouh, Michael E; Feld, Jordan J; Fox, Susan; Furlan, Andrea D; Goligher, Ewan C; Hodgson, David C; Inman, Robert D; Juando Prats, Clara; Lamontagne, Francois; Langlois, Marc-Andre; Levin, Adeera; Mansfield, Avril; Manske, Sarah L; McMaster, W. Robert; Mylopoulos, Maria; Oza, Amit M; Papaioannou, Alexandra; Pinto, Andrew D; Quinn, Kieran L; Rahman, Proton; Razak, Fahad; Richard, Nicolas; Richardson, Harriet; Sander, Beate H; Sellmann, Susanna; Stelfox, Henry T; Straus, Sharon E; Tartaglia, Maria Carmela; Tobe, Sheldon W; Tomlinson, George A; Verma, Amol; Walmsley, Sharon L; Wu, Robert; Xu, Wei

Keywords: Adaptive Trials; Biostatistics; Clinical Trials; Hqp Development; Job Shadowing; Mentorship; Pedogagy; Training

$4,314,242

Diabetes Connections - Shookaawaapinewin Mamow Wicihiwewin: Reorienting diabetes care in First Nations communities in Northwestern Ontario through empowerment, autonomy and ownership for health and wellbeing

Co-investigatorCIHR2022Team Grant: Diabetes Prevention and Treatment in Indigenous Communities: R&W

Principal investigators: Sodhi, Sumeet K; Johnson, Ralph

Keywords: Chronic Disease Model; Community Health Workers; Diabetes; Implementation Science; Indigenous Health; Two Eyed Seeing

$2,000,000

Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)

Principal investigatorCIHR2022Training Grant: Clinical Trials Training Platforms - Indirect Costs

Keywords: Adaptive Trials; Biostatistics; Clinical Trials; Hqp Development; Job Shadowing; Mentorship; Pedogagy; Training

$1,078,562

Secondary Prevention Community Heart Outcomes Improvement and Cholesterol Education Study (Secondary CHOICES)

Co-investigatorCIHR2021Project Grant - Priority Announcement: Health Services and Policy Research

Principal investigators: Udell, Jacob A

Keywords: Audit And Feedback; Health Equity; Secondary Prevention Of Cardiovascular Disease

$100,000

Alcohol consumption and change in blood pressure: evidence synthesis of 24 hour trial data and modelling of intervention effects

Co-investigatorCIHR2020Project Grant

Principal investigators: Roerecke, Michael

Keywords: Alcohol Consumption; Blood Pressure; Drinking Patterns; Hypertension; Meta-Analysis; Systematic Review

$120,000

Using big data to conduct innovative cardiovascular clinical trials

Co-investigatorCIHR2016Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant

Principal investigators: Tu, Jack V; Tepper, Joshua D; Farkouh, Michael E; Lindsay, Mary Patrice; Udell, Jacob A

Keywords: Administrative Data; Big Data; Cardiology; Implementation Science; Innovative Randomized Clinical Trials; Statins

$2,999,996

DREAM-GLOBAL: Diagnosing hypeRtension - Engaging Action and Management in Getting LOwer Bp in Aboriginal and LMIC - A Research Proposal

Principal investigatorCIHR2011Team Grant: Implem Res on Hypertension in Low/Middle Income Countries

Principal investigators: Liu, Peter P; Campbell, Norman R; Tobe, Sheldon W; Yeates, Karen

Keywords: Aboriginal Communities; Cell Phones; Chronic Disease Management; Community Intervention; Health Policy; Hypertension; Information Technology; Lmic - Tanzania; Randomized Trial; Sodium Reduction

$1,804,101

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Sheldon Tobe

Research

Latest papers

Latest funding

Consensus Methodology for the Canadian Brain and Heart Clinical Practice Guidelines

Appraising the Quality of Patient Decision Aids for Brain and Heart Health: An Environmental Scan with a Health Equity Lens.

The Role of Renal Denervation in the Treatment of Hypertension in Canada: A Case-Based Discussion from the Canadian Hypertension Specialists Society.

Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1

Uptake of novel evidence-based therapies in patients with type 2 diabetes after a cardiovascular event: insights from CANHEART.

Cost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Canada.

Patient Perspectives on a Pilot Virtual Follow-up Program After Hypertensive Disorders of Pregnancy: A Qualitative Study

Association of prior outpatient diabetes screening with cardiovascular events and mortality among people with incident diabetes: a population-based cohort study.

Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease.

Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident&#xa0;Heart&#xa0;Failure.

Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)

Diabetes Connections - Shookaawaapinewin Mamow Wicihiwewin: Reorienting diabetes care in First Nations communities in Northwestern Ontario through empowerment, autonomy and ownership for health and wellbeing

Canadian Training Platform for Trials Leveraging Existing Networks (CAN-TAP-TALENT)

Secondary Prevention Community Heart Outcomes Improvement and Cholesterol Education Study (Secondary CHOICES)

Alcohol consumption and change in blood pressure: evidence synthesis of 24 hour trial data and modelling of intervention effects

Using big data to conduct innovative cardiovascular clinical trials

DREAM-GLOBAL: Diagnosing hypeRtension - Engaging Action and Management in Getting LOwer Bp in Aboriginal and LMIC - A Research Proposal

Frequent collaborators

Catherine Clase

Salim Yusuf

Peter Liu

Richard Lewanczuk

Hwee Teoh

Koon Teo

Eva Lonn

Sonia Anand

Nancy Edwards

Louise Moist

Wade Thompson

Hertzel Gerstein

Shivinder Jolly

Robert Kalyesubula

Karen Tu

Dawn Stacey

Nadia Khan

Rob Beanlands

Deborah Zimmerman

Jodi Edwards

Andrew Simor

Karen Yeates

Alanna Weisman

Shun Fu Lee

Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident Heart Failure.