Research
Hertzel C. Gerstein MD MSc FRCPC FCAHS FRSC is a Canadian endocrinologist, clinical epidemiologist, and internationally recognized diabetes researcher. He is Professor of Medicine at McMaster University, where he holds the McMaster-Sanofi Population Health Institute Chair in Diabetes Research and Care. He is also the Interim Executive Director of the Population Health Research Institute, which is jointly governed by McMaster University and HHS Hamilton Health Sciences (HHS). His research firmly established international long-term diabetes-focused outcomes RCTs as the norm to support Evidence-Based Diabetes Care. Trials he designed and led have randomized more than 90,000 people with either diabetes or prediabetes, and have studied and identified clinically important, life-saving diabetes therapies. These plus many biomarker studies, editorials, and epidemiologic analyses have been widely cited with an h-index of 117. His awards include the 2012 Canadian Diabetes Association’s Lifetime Achievement Award and the 2022 American Diabetes Association’s Outstanding Achievement in Clinical Diabetes Research Award.
Research areas are derived from OpenAlex topics of their publications.
From the 150 most recent of 893 publications.
Estimating the True MACE Benefits From Tirzepatide in SURPASS-CVOT Using an Imputed Placebo Analysis of REWIND.
Sattar N, Gerstein HC, D'Alessio D, Bhatt DL, Buse JB, Del Prato S, Kahn SE, Lincoff AM, McGuire DK, Nauck MA
Glucagon-like peptide-1 receptor agonists and Wernicke encephalopathy: A pharmacovigilance study and literature review
Lev D, Leibowitz A, Lang A, Shlomai G, Twig G, Eden-Friedman Y, Engel T, Cukierman-Yaffe T, Dankner R, Gerstein HC
Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
Huerta-Chagoya A, Kim J, Mandla R, Lu Y, Suzuki K, Petty LE, Ng HK, Choi J, Lee S, Rout M
Thyroid, Celiac, and Other Autoimmune Diseases and the Risk of Incident Type 1 Diabetes in Young Adulthood
Twig G, Simchoni M, Dym I, Vinograd A, Bendor CD, Bardugo A, Tsur AM, Zucker I, Lutski M, Derazne E
Combining GLP-1 Receptor Agonists and SGLT2 Inhibitors for Cardiorenal Prevention Evidence From Randomized Outcomes Trials
Gerstein HC, Sattar N
Delayed puberty and early-onset type 2 diabetes risk: a nationwide cohort study of male adolescents in Israel
Pinhas-Hamiel O, Simchoni M, Derazne E, Bendor CD, Tsur AM, Vinograd A, Lutski M, Zucker I, Singhal V, Gerstein HC
Normal-Range Gestational Glucose Challenge Test and Incident Type 2 Diabetes: A Population-Based Cohort Study.
Nitecki M, Vinograd A, Bardugo A, Bendor C, Derazne E, Tsur AM, Cukeirman-Yaffe T, Federspiel JJ, Kuller JA, Afek A
Cardiovascular Risk Reduction With GLP-1 RA Drugs
Pigeyre M, Gerstein HC
Rationale and design of a parallel randomised trial of a plant‐based intensive lifestyle intervention for diabetes remission: The REmission of diabetes using a PlAnt‐based weight loss InteRvention (REPAIR) trial
McKay B, Chaar DE, Paquette M, Vallis M, Sherifali D, Oh P, Marzolini S, Dasgupta K, Booth G, Lean M
Dulaglutide and neurodegeneration biomarkers: REWIND post hoc analysis
Wilson JM, Dage JL, Qian H, Irelan CL, Crowder HS, Duffin KL, Mintun M, Brooks DA, Gerstein HC, Bethel MA
Courses taught
1- Graduate
Independent Study I
GLOBHTH 715 · last taught 2025
Research institutes and memberships
- Centre for Metabolism, Obesity and Diabetes Research (MODR)
Frequent collaborators
203Salim Yusuf
Medicine
201 shared papers, latest 2026
Jackie Bosch
Rehabilitation Science
83 shared papers, latest 2024
Guillaume Pare
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78 shared papers, latest 2026
Sonia Anand
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73 shared papers, latest 2026
Zubin Punthakee
Medicine
48 shared papers, latest 2026
Eva Lonn
Medicine
47 shared papers, latest 2023
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