Sujeenthar Tharmalingam, Laurentian University

Research

radiation biology Genetic Engineering apoptosis cell cycle CRISPR DNA damage response DNA repair ionizing radiation

Latest papers

Molecular crosstalk between gas transmitters and catecholamine biosynthesis pathways: a narrative review.
Medical gas research · 2027
Nucleic Acid Amplification Tests for Candida Species Identification: A Systematic Review of Diagnostic Performance
Pathogens · 2026 · senior author
Transcriptomic profiling of lentoid bodies highlights potential mechanisms of radiation-induced cataracts
International Journal of Radiation Biology · 2026

All 48 publications

Latest funding

Characterization of Circulating Tumor DNA Dynamics in Colorectal Cancer Cell Models
CIHR · 2026 · Supervisor
$6,000
Deploying Viruses and Machine Learning for Climate Change Mitigation
SSHRC · 2024 · Principal investigator
$125,000
A microbial sponge to mine the critical mineral gallium
NSERC · 2023 · Principal investigator
$200,000

All 9 grants and awards

48 publications.

01

Molecular crosstalk between gas transmitters and catecholamine biosynthesis pathways: a narrative review.

Dingley R, Tharmalingam S, Tai TC

Medical gas research2027

DOI: 10.4103/mgr.medgasres-d-26-00004 PMID: 42734455

02

Nucleic Acid Amplification Tests for Candida Species Identification: A Systematic Review of Diagnostic Performance

Czajka KM, Bilgasem A, Al-Jumaili YA, Kitching D, Buchan G, Nair A, Reich M, Ijomah C, Saikrishna GE, Verschoor C

Pathogens20261 citationsSenior author

DOI: 10.3390/pathogens15070753

03

Transcriptomic profiling of lentoid bodies highlights potential mechanisms of radiation-induced cataracts

Vigneux G, Tharmalingam S, Thome C

International Journal of Radiation Biology2026

DOI: 10.1080/09553002.2026.2708814

04

Molecular Mechanisms of Radiation Resistance in Breast Cancer: A Systematic Review of Radiosensitization Strategies

Mageau E, Derbowka R, Dickinson N, Lefort N, Kovala AT, Boreham DR, Tai TC, Thome C, Tharmalingam S

Current Issues in Molecular Biology20259 citationsSenior author

DOI: 10.3390/cimb47080589

05

Signs and symptoms of oral candidiasis associated with health factors and resistant Candida infections in a Northern Ontario patient cohort

Czajka KM, Verschoor CP, Santi SA, Brabant-Kirwan D, Kusnierczyk MH, Venkataraman K, Appanna VD, Singh R, Tharmalingam S, Saunders DP

Frontiers in Oral Health20255 citations

DOI: 10.3389/froh.2025.1661524

06

Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure

Lionel GJ, Derbowka R, Sreetharan S, Bel J, Dougherty J, Boreham DR, Tai TC, Thome C, Lees SJ, Tharmalingam S

Dose-Response20252 citationsSenior author

DOI: 10.1177/15593258251391602

07

FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks

Al-Khayyat W, Laframboise T, Dougherty J, Mendonca MS, Boreham DR, Tai TC, Thome C, Tharmalingam S

Frontiers in Cell and Developmental Biology20251 citationsSenior author

DOI: 10.3389/fcell.2025.1659986

08

Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial–Mesenchymal Transition

Dickinson N, Murray A, Davis M, Marshall-Bergeron K, Dougherty J, Al-Khayyat W, Narendrula R, Lavoie M, Mageau E, Derbowka R

International Journal of Molecular Sciences2025Senior author

DOI: 10.3390/ijms26199611

09

Growth Restriction in Balb/c Mice Irradiated With X-Rays During Late Gestation: Role of Irradiation Timing, Dose Fractionation and Adaptive Response

Sreetharan S, King T, Thome C, Khaper N, Boreham DR, Tharmalingam S, Lees SJ, Tai TC

Dose-Response2025

DOI: 10.1177/15593258251395327

10

Metabolism of Terephthalic Acid by a Novel Bacterial Consortium Produces Valuable By-Products.

Slobodian MR, Jillings D, Barot AK, Dougherty J, Passi K, Tharmalingam S, Appanna VD

Microorganisms2025

DOI: 10.3390/microorganisms13092082 PMID: 41011413

Characterization of Circulating Tumor DNA Dynamics in Colorectal Cancer Cell Models

SupervisorCIHR2026Undergraduate Student Research Awards (USRA)

Principal investigators: Olufowobi, Similoluwa

Keywords: Apoptosis; Dna Fragments; Necrosis; Tumor Cells

$6,000

Deploying Viruses and Machine Learning for Climate Change Mitigation

Principal investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Tharmalingam, Sujeenthar

$125,000

A microbial sponge to mine the critical mineral gallium

Principal investigatorNSERC2023Alliance Grants

Principal investigators: Tharmalingam, Sujeenthar ST

Keywords: Accelerated Evolution; Bauxite; Bioleaching; Biotechnology; Chelator; Gallium; Genetic Engineering; Microbiology; Mine Tailings; Mining

$200,000

Elucidating the role of long non-coding RNA (lncRNA) in the DNA damage response

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Tharmalingam, Sujeenthar

Keywords: dna damage response; long non-coding rna; ionizing radiation; dna repair; cell cycle; apoptosis; senescence; crispr; radiation biology; molecular genetics

$84,000

Biomass waste to value

Principal investigatorNSERC2022Alliance Grants

Principal investigators: Tharmalingam, Sujeenthar ST

Keywords: Abiotic stress; Accelerated Evolution; Agriculture Waste Management; Biofuels; Genetic Engineering; Genetics; Hemicellulose; Microbiology; Molecular Biology

$60,000

Elucidating the role of long non-coding RNA (lncRNA) in the DNA damage response

Principal investigatorNSERC2022Discovery Launch Supplement

Principal investigators: Tharmalingam, Sujeenthar

$12,500

Bioengineering of microbial systems to remediate plastic pollutants

Principal investigatorNSERC2021Alliance Grants

Principal investigators: Tharmalingam, Sujeenthar

$30,000

Design and development of an at-home COVID-19 detection kit with custom-engineered microbial sensors _x000d_ _x000d_ _x000d_ _x000d_

Principal investigatorNSERC2020Alliance Grants

Principal investigators: Tharmalingam, Sujeenthar

$30,000

Harnessing genetically modified microbes to combat the effects of ionizing radiation

Principal investigatorSSHRC2019New Frontiers in Research Fund - Exploration

Principal investigators: Tharmalingam, Sujeenthar

$273,175

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biology
Medicine
Oncology
Medical Sciences
Physics & Astronomy

Co-authors at Laurentian University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Christopher Thome

Physics & Astronomy

21 shared papers, latest 2026

Ian Stuart Dayes

Oncology

1 shared papers, latest 2023

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their SSHRC grant from 2024

Subject: Prospective PhD student: radiation biology Dear Professor Tharmalingam, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Molecular crosstalk between gas transmitters and catecholamine biosynthesis pathways: a narrative review." (2027), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your SSHRC-funded project "Deploying Viruses and Machine Learning for Climate Change Mitigation" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Sujeenthar Tharmalingam

Research

Latest papers

Latest funding

Molecular crosstalk between gas transmitters and catecholamine biosynthesis pathways: a narrative review.

Nucleic Acid Amplification Tests for Candida Species Identification: A Systematic Review of Diagnostic Performance

Transcriptomic profiling of lentoid bodies highlights potential mechanisms of radiation-induced cataracts

Molecular Mechanisms of Radiation Resistance in Breast Cancer: A Systematic Review of Radiosensitization Strategies

Signs and symptoms of oral candidiasis associated with health factors and resistant Candida infections in a Northern Ontario patient cohort

Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure

FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks

Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial–Mesenchymal Transition

Growth Restriction in Balb/c Mice Irradiated With X-Rays During Late Gestation: Role of Irradiation Timing, Dose Fractionation and Adaptive Response

Metabolism of Terephthalic Acid by a Novel Bacterial Consortium Produces Valuable By-Products.

Characterization of Circulating Tumor DNA Dynamics in Colorectal Cancer Cell Models

Deploying Viruses and Machine Learning for Climate Change Mitigation

A microbial sponge to mine the critical mineral gallium

Elucidating the role of long non-coding RNA (lncRNA) in the DNA damage response

Biomass waste to value

Elucidating the role of long non-coding RNA (lncRNA) in the DNA damage response

Bioengineering of microbial systems to remediate plastic pollutants

Design and development of an at-home COVID-19 detection kit with custom-engineered microbial sensors _x000d_ _x000d_ _x000d_ _x000d_

Harnessing genetically modified microbes to combat the effects of ionizing radiation

Frequent collaborators

Douglas Robert Boreham

Christopher Thome

Chris Verschoor

Joanna Wilson

Dawn Bowdish

Sameer Parpia

Ian Stuart Dayes