Faculty profile

Boris Zhorov

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Professor EmeritusBiochemistry & Biomedical SciencesMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

From the 150 most recent of 281 publications.

01

Missense mutation causes multiple defects in Nav1.4 channel gating and leads to an SCN4A-associated overlap phenotype

Tikhonova TB, Sharkov AA, Murtazina AF, Mashkovtseva NV, Zhorov BS, Vassilevski AA

The Journal of General Physiology20261 citations
02

Functional characterization of voltage-gated sodium channels in two mirid pests and identification of kdr mutations in pyrethroid resistant Lygus lineolaris population

Du Y, Scheibener S, Zhu Y-C, Perera OP, Reddy GVP, Zhorov BS

Insect Biochemistry and Molecular Biology20261 citationsSenior author
03

Role of TRPM4 ion channel in pediatric arrhythmic syndromes

Melnik OV, Kulichik OE, Zaytseva AK, Kofeynikova OA, Fetisova SG, Tarnovskaya SI, Fomicheva YV, Vasichkina ES, Zhorov BS, Kalinina OV

World Journal of Clinical Pediatrics2026
04

FUNCTIONAL ALTERATIONS OF VOLTAGE-GATED SODIUM CHANNELS Nav1.4 WITH REPLACEMENTS IN THE LINKER BETWEEN III AND IV REPEATS DETECTED IN RUSSIAN PATIENTS

Tikhonova T, Zhorov B, Sharkov A, Murtazina A, Mashkovtseva N, Vassilevski A

2026
05

Differential Na+ chelation underlies opposite effects of aconitine and bulleyaconitine on sodium channel permeation

Zhorov BS

The Journal of General Physiology2026First author
06

3D-aligned tetrameric ion channels with universal residue labels for comparative structural analysis

Tikhonov DB, Korkosh VS, Zhorov BS

Biophysical Journal20256 citationsSenior author
07

Predicting the Damaging Potential of Uncharacterized KCNQ1 and KCNE1 Variants

Tarnovskaya SI, Zhorov BS

International Journal of Molecular Sciences20254 citationsSenior author
08

Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor

Singh A, Zhorov BS, Yanez-Guerra LA, Aleotti A, Koens CC, Yanartas CD, Song Y, Miguez Cabello FJ, Bowie D, Senatore A

Communications Biology20254 citations
09

Golden Gate cloning enables efficient concatemer construction for biophysical analysis of heterozygous potassium channel variants from patients with epilepsy

Gigolaev AM, Iureva DA, Lagosha SV, Brazhe AR, Zhorov BS, Vassilevski AA

International Journal of Biological Macromolecules20253 citations
10

Charge Reversal of the Uppermost Arginine in Sliding Helix S4-I Affects Gating of Cardiac Sodium Channel

Kulichik OE, Zaytseva AK, Kostareva AA, Zhorov BS

International Journal of Molecular Sciences20252 citationsSenior authorOpen Access
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Applying for
Subject: Prospective PhD student: Ion channel regulation and function Dear Professor Zhorov, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Missense mutation causes multiple defects in Nav1.4 channel gating and leads to an SCN4A-associated overlap phenotype" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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