Faculty profile

David Hing-kwei Chui

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Professor EmeritusPathology & Molecular MedicineMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

From the 150 most recent of 310 publications.

01

Pharmacologic induction of PGC‐1α stimulates fetal haemoglobin gene expression

Sun Y, Habara A, Le CQ, Nguyen N, Chen R, Murphy GJ, Chui DHK, Steinberg MH, Cui S

British Journal of Haematology202213 citations
02

Clinical phenotypes of three children with sickle cell disease caused by HbS/Sicilian (δβ)0‐thalassemia deletion

Aygun B, Bello A, Thompson AA, Davis L, Sun Y, Luo H, Cui S, Chui DHK

American Journal of Hematology20225 citationsSenior author
03

Alpha‐thalassemia. Case report alpha‐thalassemia in a Costa Rican family, A case report

Solano‐Vargas M, Chui DHK, Rodriguez‐Romero W

Clinical Case Reports20211 citations
04

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia

Xu S, Luk K, Yao Q, Shen AH, Zeng J, Wu Y, Luo H-Y, Brendel C, Pinello L, Chui DHK

Blood201979 citationsSenior author
05

Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis

Le CQ, Myers G, Habara A, Jearawiriyapaisarn N, Murphy GJ, Chui DHK, Steinberg MH, Engel JD, Cui S

Blood201918 citations
06

BCL2L1 is associated with γ-globin gene expression

Dai Y, Shaikho EM, Perez J, Wilson CA, Liu LY, White MR, Farrell JJ, Chui DHK, Sebastiani P, Steinberg MH

Blood advances201916 citations
07

The association of HBG2, BCL11A, and HMIP polymorphisms with fetal hemoglobin and clinical phenotype in Iraqi Kurds with sickle cell disease

Al‐Allawi N, Qadir SMA, Puehringer H, Chui DHK, Farrell JJ, Oberkanins C

International Journal of Laboratory Hematology201912 citations
08

Editing Aberrant Splice Sites with Cas9 and Cas12a Efficiently Restores beta-Globin Expression in beta-Thalassemia

Luk K, Xu S, Yao Q, Shen AH, Zeng J, Wu Y, Luo H-Y, Brendel C, Pinello L, Chui DHK

Molecular Therapy2019Senior author
09

A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression

Morrison TA, Wilcox I, Luo H-Y, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK

Blood Cells, Molecules, and Diseases201848 citationsSenior author
10

Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells

Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH

Stem Cells201839 citations
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Subject: Prospective PhD student: Hemoglobinopathies and Related Disorders Dear Professor Chui, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Pharmacologic induction of PGC‐1α stimulates fetal haemoglobin gene expression" (2022), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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