Dennis Robert Mccalla

Research

Research areas, by share of publications

Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology
DNA and Nucleic Acid ChemistryBiochemistry, Genetics and Molecular Biology
Pharmaceutical and Antibiotic Environmental ImpactsEnvironmental Science
DNA Repair MechanismsBiochemistry, Genetics and Molecular Biology

Research areas are derived from OpenAlex topics of their publications.

Latest papers

The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms.
Genetics · 1992 · senior author
The mutational specificity of 2-(2-furyl)-3-(5-nitro-2-furyl)-acrylamide (AF2) in the lacI gene of Escherichia coli
Carcinogenesis · 1991 · senior author
The action of 1-nitroso-8-nitroprene in Eachericia coli: DNA adduct formation and mutational consequeces in the absence of necleotide excision-repair
Carcinogenesis · 1991 · senior author

All 82 publications

Latest funding

Dna damage and mutation spectra of nitro-compounds
NSERC · 1991 · Principal investigator
$84,000

All 1 grants and awards

Researchers with similar interests

Sara Andres

Biochemistry & Biomedical Sciences

DNA Repair Mechanisms, DNA and Nucleic Acid Chemistry

Katherine Bujold

Chemistry & Chemical Biology

DNA and Nucleic Acid Chemistry

Rashid Abu-Ghazalah

School of Engineering Technology

DNA and Nucleic Acid Chemistry

Gregory Jeffries

Family Medicine

DNA and Nucleic Acid Chemistry

Nghi Phan

Family Medicine

Carcinogens and Genotoxicity Assessment, DNA Repair Mechanisms

Avik Ghoshdastidar

Chemistry & Chemical Biology

Pharmaceutical and Antibiotic Environmental Impacts

82 publications.

01

The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms.

Lambert IB, Gordon AJ, Glickman BW, McCalla DR

Genetics199216 citationsSenior author

DOI: 10.1093/genetics/132.4.911

02

The mutational specificity of 2-(2-furyl)-3-(5-nitro-2-furyl)-acrylamide (AF2) in the lacI gene of Escherichia coli

Lambert IB, Chin TA, Bryant DW, Gordon JE, Glickman BW, McCalla DR

Carcinogenesis199110 citationsSenior author

DOI: 10.1093/carcin/12.1.29

03

The action of 1-nitroso-8-nitroprene in Eachericia coli: DNA adduct formation and mutational consequeces in the absence of necleotide excision-repair

Lambert IB, Gordon AJE, Bryant DW, Glickman BW, McCalla DR

Carcinogenesis19919 citationsSenior author

DOI: 10.1093/carcin/12.5.879

04

Comparison of three assays for genetic effects of antineoplastic drugs on cancer patients and their nurses

Krepinsky A, Bryant DW, Davison L, Young B, Heddle J, McCalla DR, Douglas G, Michalko K

Environmental and Molecular Mutagenesis199030 citations

DOI: 10.1002/em.2850150205

05

Formation and persistence of DNA adducts in rats following intraperitoneal administration of 1,8-dinitropyrene

Norman CA, Lambert IB, Davison LM, Bryant DW, McCalla DR

Carcinogenesis19904 citationsSenior author

DOI: 10.1093/carcin/11.6.1037

06

Proposed Plan for a Unified Approach for Evaluating Nitrofuran Residues

McCalla DR

Drug Metabolism Reviews19903 citationsFirst author

DOI: 10.3109/03602539008991475

07

Comparison of in vivo somatic cell mutation, chromosome aberration, sister chromatid exchange, micronuclei formation and urine mutagenicity in steel foundry workers.

Tomkins DJ, McCalla DR, Gibson ES

Progress in Clinical and Biological Research19903 citations

08

Mutations Induced in the lacI Gene of E. coli by 1-Nitroso-8-Nitropyrene and Furylfuramide: The Influence of Plasmid pKM101 and Excision Repair on the Mutational Spectrum

Lambert IB, Gordon AJE, Chin TA, Bryant DW, Glickman BW, McCalla DR

1990Senior author

DOI: 10.1007/978-1-4615-3800-4_15

09

SHORT COMMUNICATION: DNA adduct formation in primary rabbit tracheal epithelial cells following treatment with 1, 8-dinitropyrene and its partially reduced derivative, 1-nitro-8-nitrosopyrene

Norman CA, Lambert IB, Davison LM, Bryant DW, McCalla DR

Carcinogenesis19891 citationsSenior author

DOI: 10.1093/carcin/10.7.1323

10

Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems

Gupta RS, Bromke A, Bryant DW, Gupta R, Singh B, McCalla DR

Mutagenesis198744 citationsSenior author

DOI: 10.1093/mutage/2.3.179

Dna damage and mutation spectra of nitro-compounds

Principal investigatorNSERC1991Discovery Grants Program - Group

Principal investigators: McCalla, Dennis

$84,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biochemistry & Biomedical Sciences
Pathology & Molecular Medicine

Co-authors at McMaster University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Jacob Mordechai Rosenfeld

Pathology & Molecular Medicine

1 shared papers, latest 1983

Radhey Gupta

Biochemistry & Biomedical Sciences

1 shared papers, latest 1987

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student: Carcinogens and Genotoxicity Assessment Dear Professor Mccalla, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms." (1992), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Open in email