Faculty profile

Lennard Polycarp Niles

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Professor EmeritusPsychiatry & Behavioural NeurosciencesMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

97 publications.

01

5-Azacytidine upregulates melatonin MT1 receptor expression in rat C6 glioma cells: oncostatic implications

Hartung EE, Mukhtar SZ, Shah SM, Niles LP

Molecular Biology Reports20209 citationsSenior author
02

Epigenetic regulation of melatonin receptors in neuropsychiatric disorders

Bahna SG, Niles LP

British Journal of Pharmacology201837 citationsSenior authorOpen Access
03

Epigenetic induction of melatonin MT1 receptors by valproate: Neurotherapeutic implications

Bahna SG, Niles LP

European Neuropsychopharmacology201716 citationsSenior author
04

Bilateral upregulation of α-synuclein expression in the mouse substantia nigra by intracranial rotenone treatment

Carriere CH, Kang NH, Niles LP

Experimental and Toxicologic Pathology201716 citationsSenior author
05

Chronic low-dose melatonin treatment maintains nigrostriatal integrity in an intrastriatal rotenone model of Parkinson’s disease

Carriere CH, Kang NH, Niles LP

Brain Research201640 citationsSenior author
06

Altered melatonin MT1 receptor expression in the ventral midbrain following 6-hydroxydopamine lesions in the rat medial forebrain bundle

Kang NH, Carriere CH, Bahna SG, Niles LP

Brain Research20165 citationsSenior author
07

Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells

Pan Y, Niles LP

Molecular and Cellular Endocrinology201521 citationsSenior author
08

Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease: A Randomized Clinical Trial

Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D

JAMA Neurology2014243 citations
09

Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson’s disease

Carriere CH, Kang NH, Niles LP

Neuroscience201441 citationsSenior author
10

Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid

Almutawaa W, Kang NH, Pan Y, Niles LP

Basic and Clinical Pharmacology and Toxicology201425 citationsSenior author
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Applying for
Subject: Prospective PhD student: Circadian rhythm and melatonin Dear Professor Niles, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "5-Azacytidine upregulates melatonin MT1 receptor expression in rat C6 glioma cells: oncostatic implications" (2020), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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