Faculty profile

Silvia Bacchetti

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Professor EmeritusPathology & Molecular MedicineMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

130 publications.

01

The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells

Castro-Vega LJ, Jouravleva K, Ortiz-Montero P, Liu W-Y, Galeano JL, Romero M, Popova T, Bacchetti S, Vernot JP, Londoño-Vallejo A

Carcinogenesis201540 citations
02

Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas

Castro-Vega LJ, Jouravleva K, Liu W-Y, Martinez C, Gestraud P, Hupé P, Servant N, Albaud B, Gentien D, Gad S

Carcinogenesis201324 citations
03

Estrogen-Dependent Dynamic Profile of eNOS-DNA Associations in Prostate Cancer

Nanni S, Aiello A, Re A, Guffanti A, Benvenuti V, Colussi C, Castro-Vega LJ, Felsani A, Londono-Vallejo A, Capogrossi MC

PLoS ONE201323 citations
04

The heterochromatic chromosome caps in great apes impact telomere metabolism

Novo C, Arnoult N, Bordes W-Y, Castro-Vega L, Gibaud A, Dutrillaux B, Bacchetti S, Londoño-Vallejo A

Nucleic Acids Research (NAR)201314 citations
05

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals

Goeman F, Manni I, Artuso S, Ramachandran B, Toietta G, Bossi G, Rando G, Cencioni C, Germoni S, Straino S

Molecular Biology of the Cell201235 citations
06

Silencing of GSTP1, a Prostate Cancer Prognostic Gene, by the Estrogen Receptor-β and Endothelial Nitric Oxide Synthase Complex

Re A, Aiello A, Nanni S, Grasselli A, Benvenuti V, Pantisano V, Strigari L, Colussi C, Ciccone S, Mazzetti AP

Endocrinology201124 citations
07

The role of nuclear endothelial nitric oxide synthase in the endothelial and prostate microenvironments

Nanni S, Grasselli A, Benvenuti V, Aiello A, Pantisano V, Re A, Gaetano C, Capogrossi MC, Bacchetti S, Pontecorvi A

Hormone Molecular Biology and Clinical Investigation20115 citations
08

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londoño-Vallejo A

Proceedings of the National Academy of Sciences of the United States of America2009165 citations
09

Endothelial NOS, estrogen receptor β, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer

Nanni S, Benvenuti V, Grasselli A, Priolo C, Aiello A, Mattiussi S, Colussi C, Lirangi V, Illi B, D’Eletto M

Journal of Clinical Investigation2009112 citations
10

The telomerase tale in vascular aging: regulation by estrogens and nitric oxide signaling

Farsetti A, Grasselli A, Bacchetti S, Gaetano C, Capogrossi MC

Journal of applied physiology200932 citations
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Applying for
Subject: Prospective PhD student: Telomeres, Telomerase, and Senescence Dear Professor Bacchetti, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells" (2015), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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