Faculty profile
Ted Warkentin
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Dr. Theodore (Ted) E. Warkentin, MD, BSc(Med), FRCP(C), FACP, is a clinical and laboratory hematologist and transfusion medicine director at Hamilton General Hospital, and is a Professor in the Department of Pathology and Molecular Medicine, and the Department of Medicine, at McMaster University, in Hamilton, Ontario, Canada. His clinical work and related research focuses on acquired thrombocytopenias and coagulopathies—most notably the topics of “heparin-induced thrombocytopenia (HIT)” and "ischemic limb gangrene with pulses" (symmetrical peripheral gangrene/purpura fulminans associated with critical illness). Dr. Warkentin devised the “4Ts”, a widely-used scoring system for evaluating clinical probability of HIT. He is a co-winner (with Prof. John Kelton) of the 2015 Prix Galien Canada Prize, the highest award for Canadian scientists who have made significant advances in pharmaceutical research. He also identified “spontaneous HIT syndrome” (a rare HIT-mimicking disorder that occurs despite absence of preceding heparin exposure), and other examples of “autoimmune HIT”—a group of unusual clotting disorders that provides insight into “vaccine-induced immune thrombotic thrombocytopenia (VITT),” a novel prothrombotic anti-PF4 platelet-activating disorder that rarely is caused by adenoviral vector vaccines. He has co-edited (with Prof. Greinacher) 5 editions of a book, Heparin-Induced Thrombocytopenia, has authored 107 book chapters and 400 peer-reviewed articles, and has given over 890 lectures to national and international audiences.
Research areas are derived from OpenAlex topics of their publications.
From the 150 most recent of 611 publications.
Adenoviral Core Protein VII-Driven Cross-Reactivity of Anti-PF4 Antibodies as a Trigger for VITT Pathogenesis
Wang JJ, Schönborn L, Warkentin TE, Müller L, Thiele T, Ulm L, Völker U, Ameling S, Franzenburg S, Kaderali L
Prolonged Heparin Re‐Exposure in a Patient With Previous Heparin‐Induced Thrombocytopenia (HIT)
Pleyer C, Ney G, Nghiem K, Kalsi S, Bolan C, Calvo KR, de Melo MKS, Stewart DR, Maiarana J, Kanuri A
Antibody Fingerprints Linking Adenoviral Anti-PF4 Disorders
Wang JJ, Schönborn L, Warkentin TE, Chataway T, Grosse L, Simioni P, Moll S, Greinacher A, Gordon TP
Rescue Therapy in Chronic Prothrombotic Autoimmune Anti-PF4 Disorder
Lindhoff-Last E, Schönborn L, Zaninetti C, Warkentin TE, Greinacher A
An evaluation of the clinical impacts of 7‐day platelets
Ning S, Gabarin N, Li N, Liu Y, Lucier K, Barty R, Acker J, Webert KE, Warkentin TE, Arnold DM
Vaccine‐induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources
Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE
Platelet-activating anti-PF4 disorders: An overview
Warkentin TE
Platelet-activating anti-PF4 antibodies mimicking VITT antibodies in an unvaccinated patient with monoclonal gammopathy
Greinacher A, Langer F, Schonborn L, Thiele T, Haddad M, Renne T, Rollin J, Gruel Y, Warkentin TE
Treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT)
Gabarin N, Arnold DM, Nazy I, Warkentin TE
Frequent collaborators
89John Kelton
Medicine
150 shared papers, latest 2021
Catherine Pauline Ma Hayward
Pathology & Molecular Medicine
65 shared papers, latest 2007
Donald Arnold
Medicine
55 shared papers, latest 2023
Mark Crowther
Medicine
51 shared papers, latest 2021
Ishac Nazy
Medicine
29 shared papers, latest 2022
Nancy Heddle
Medicine
22 shared papers, latest 2023
Researchers with similar interests
Geoff Rosenblood
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Heparin-Induced Thrombocytopenia and Thrombosis, Platelet Disorders and Treatments
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Heparin-Induced Thrombocytopenia and Thrombosis, Platelet Disorders and Treatments
Ishac Nazy
Medicine
Heparin-Induced Thrombocytopenia and Thrombosis, Platelet Disorders and Treatments
Wendy Lim
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Venous Thromboembolism Diagnosis and Management, Platelet Disorders and Treatments
John Kelton
Medicine
Heparin-Induced Thrombocytopenia and Thrombosis, Platelet Disorders and Treatments
Donald Arnold
Medicine
Heparin-Induced Thrombocytopenia and Thrombosis, Platelet Disorders and Treatments
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