Faculty profile

Douglas Holdway

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ProfessorFSCIOntario Tech University

Douglas Holdway

Professor

FSCI

Ontario Tech University

Oshawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
No publications since 2021.
Principal investigator on 9 research grants (6 NSERC, 2 ONTARIO, 1 CFI), most recently in 2014.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

166

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Read how they describe their research on their Ontario Tech University profile.

Aquatic toxicology Aquatic toxicology Environmental services Fish physiology Pesticides Pulp mill effluents Water Water pollution

Latest papers

An 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes).
Aquatic toxicology (Amsterdam, Netherlands) · 2021 · senior author
Sex-Related Embryotoxicity of Pulp Mill Effluent Extracts in Medaka (Oryzias latipes) Female Leucophore-free FLFII Strain.
Environmental toxicology and chemistry · 2021 · senior author
Developmental and Full-Life Cycle Exposures to Guanylurea and Guanylurea–Metformin Mixtures Results in Adverse Effects on Japanese Medaka (Oryzias latipes)
Environmental Toxicology and Chemistry · 2019 · senior author

All 12 publications

Latest funding

Aquatic toxicity of pharmaceuticals and personal care products
NSERC · 2014 · Principal investigator
$130,000
Canada Research Chair in Aquatic Toxicology
NSERC · 2010 · Principal investigator
$1,200,000
Canada Research Chair in Aquatic Toxicology
NSERC · 2010 · Principal investigator
$200,000

All 10 grants and awards

12 publications.

An 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes).

Ussery EJ, Nielsen KM, Simmons D, Pandelides Z, Mansfield C, Holdway D

Aquatic toxicology (Amsterdam, Netherlands)202124 citationsSenior authorOpen Access

DOI: 10.1016/j.aquatox.2021.105761 PMID: 33550114

Sex-Related Embryotoxicity of Pulp Mill Effluent Extracts in Medaka (Oryzias latipes) Female Leucophore-free FLFII Strain.

Orrego R, Guchardi J, Beyger L, Barra R, Hewitt LM, Holdway D

Environmental toxicology and chemistry2021Senior author

DOI: 10.1002/etc.5115 PMID: 33978263

Developmental and Full-Life Cycle Exposures to Guanylurea and Guanylurea–Metformin Mixtures Results in Adverse Effects on Japanese Medaka (Oryzias latipes)

Erin J. Ussery, Kristin M. Nielsen, Zacharias Pandelides, Andrea E. Kirkwood, John Guchardi, Douglas Alan Holdway

Environmental Toxicology and Chemistry201938 citationsSenior author

DOI: 10.1002/etc.4403 PMID: 30835871

Effects of environmentally relevant metformin exposure on Japanese medaka (Oryzias latipes).

Ussery E, Bridges KN, Pandelides Z, Kirkwood AE, Bonetta D, Venables BJ, Guchardi J, Holdway D

Aquatic toxicology (Amsterdam, Netherlands)201875 citationsSenior author

DOI: 10.1016/j.aquatox.2018.10.003 PMID: 30336378

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Rodrigo Orrego, Craig B. Milestone, L. Mark Hewitt, John Guchardi, Tatiana Heid‐Furley, Alison H. Slade, Deborah L. MacLatchy, Douglas Alan Holdway

Environmental Toxicology and Chemistry201613 citationsSenior author

DOI: 10.1002/etc.3675 PMID: 27808443

Chronic effects of hydroxypropyl-β-cyclodextrin on reproduction in the American flagfish (Jordanella floridae) over one complete life cycle.

Anderson JC, Beyger L, Guchardi J, Holdway D

Environmental toxicology and chemistry2016Senior author

DOI: 10.1002/etc.3280 PMID: 26467440

The acute and chronic effects of endosulfan pulse-exposure on Jordanella floridae (Florida flagfish) over one complete life-cycle.

Beyger L, Orrego R, Guchardi J, Holdway D

Ecotoxicology and environmental safety2012Senior author

DOI: 10.1016/j.ecoenv.2011.09.015 PMID: 22018545

Comparative embryotoxicity of pulp mill extracts in rainbow trout (Oncorhynchus mykiss), American flagfish (Jordanella floridae) and Japanese medaka (Oryzias latipes).

Orrego R, Guchardi J, Beyger L, Krause R, Holdway D

Aquatic toxicology (Amsterdam, Netherlands)2011Senior author

DOI: 10.1016/j.aquatox.2011.04.015 PMID: 21658359

Effects of pulp and paper mill effluent extracts on liver anaerobic and aerobic metabolic enzymes in rainbow trout.

Orrego R, Pandelides Z, Guchardi J, Holdway D

Ecotoxicology and environmental safety2011Senior author

DOI: 10.1016/j.ecoenv.2010.10.042 PMID: 21095004

Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroid levels in juvenile triploid rainbow trout

Orrego R, McMaster M, Van Der Kraak G, Holdway D

Aquatic Toxicology201016 citationsSenior author

DOI: 10.1016/j.aquatox.2010.01.002

Aquatic toxicity of pharmaceuticals and personal care products

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Holdway, Douglas

$130,000

Canada Research Chair in Aquatic Toxicology

Principal investigatorNSERC2010Canada Research Chairs

Principal investigators: Holdway, Douglas

Keywords: CRC

$1,200,000

Canada Research Chair in Aquatic Toxicology

Principal investigatorNSERC2010Canada Research Chairs

Principal investigators: Holdway, Douglas

Keywords: CRC

$200,000

Interdisciplinary research using gas chromatography - mass spectrometry

Co-investigatorNSERC2009Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Forbes, Shari

$132,225

Ecotoxicological biomarker development and validation

Principal investigatorNSERC2009Discovery Grants Program - Individual

Principal investigators: Holdway, Douglas

$175,000

Effects of Toxicant Pulse-Exposure on Growth, Survival and Reproduction of Fish

Principal investigatorONTARIO2007TSTOP: TSTOP - Round 002 - 2007

Principal investigators: Holdway, Douglas

$10,000

Development of Continuous-flow Wet-laboratory and Controlled Temperature Room Facilities for the Investigation of Pulse-exposure Effects of Contaminants on Aquatic Organisms and Biomarker Validation

Principal investigatorONTARIO2005Ontario Research Fund - Research Infrastructure: Small Infrastructure Fund - Round 001 - 2004 - June

Principal investigators: Holdway, Douglas

Keywords: pulse-exposure, modifying factors, biomarkers, aquatic organisms, biosensors

$125,000

Development of continuous-flow wet-laboratory and controlled temperature room facilities for the investigation of pulse-exposure effects of contaminants on aquatic organisms and biomarker validation.

Principal investigatorCFI2004John R. Evans Leaders Fund: Canada Research Chairs Infrastructure Fund

Principal investigators: Holdway, Douglas

Keywords: pulse-exposure, modifying factors, biomarkers, aquatic organisms, biosensors

$125,000

Ecotoxicological impacts of land use on fish communities

Principal investigatorNSERC2003Discovery Grants Program - Group

Principal investigators: Holdway, Douglas

$80,000

Canada Research Chair in Aquatic Toxicology

Principal investigatorNSERC2003Canada Research Chairs

Principal investigators: Holdway, Douglas

Keywords: CRC

$201,230

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Douglas Holdway

Research

Latest papers

Latest funding

An 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes).

Sex-Related Embryotoxicity of Pulp Mill Effluent Extracts in Medaka (Oryzias latipes) Female Leucophore-free FLFII Strain.

Developmental and Full-Life Cycle Exposures to Guanylurea and Guanylurea–Metformin Mixtures Results in Adverse Effects on Japanese Medaka (Oryzias latipes)

Effects of environmentally relevant metformin exposure on Japanese medaka (Oryzias latipes).

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Chronic effects of hydroxypropyl-β-cyclodextrin on reproduction in the American flagfish (Jordanella floridae) over one complete life cycle.

The acute and chronic effects of endosulfan pulse-exposure on Jordanella floridae (Florida flagfish) over one complete life-cycle.

Comparative embryotoxicity of pulp mill extracts in rainbow trout (Oncorhynchus mykiss), American flagfish (Jordanella floridae) and Japanese medaka (Oryzias latipes).

Effects of pulp and paper mill effluent extracts on liver anaerobic and aerobic metabolic enzymes in rainbow trout.

Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroid levels in juvenile triploid rainbow trout

Aquatic toxicity of pharmaceuticals and personal care products

Canada Research Chair in Aquatic Toxicology

Canada Research Chair in Aquatic Toxicology

Interdisciplinary research using gas chromatography - mass spectrometry

Ecotoxicological biomarker development and validation

Effects of Toxicant Pulse-Exposure on Growth, Survival and Reproduction of Fish

Development of Continuous-flow Wet-laboratory and Controlled Temperature Room Facilities for the Investigation of Pulse-exposure Effects of Contaminants on Aquatic Organisms and Biomarker Validation

Development of continuous-flow wet-laboratory and controlled temperature room facilities for the investigation of pulse-exposure effects of contaminants on aquatic organisms and biomarker validation.

Ecotoxicological impacts of land use on fish communities

Canada Research Chair in Aquatic Toxicology

Frequent collaborators

Andrea Kirkwood

Glen Van Der Kraak

Denina Simmons

Dario Bonetta

Deborah MacLatchy

Glen Van Der Kraak

Douglas Holdway

Research

Latest papers

Latest funding

An 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes).

Sex-Related Embryotoxicity of Pulp Mill Effluent Extracts in Medaka (Oryzias latipes) Female Leucophore-free FLFII Strain.

Developmental and Full-Life Cycle Exposures to Guanylurea and Guanylurea–Metformin Mixtures Results in Adverse Effects on Japanese Medaka (Oryzias latipes)

Effects of environmentally relevant metformin exposure on Japanese medaka (Oryzias latipes).

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Chronic effects of hydroxypropyl-&#x3b2;-cyclodextrin on reproduction in the American flagfish (Jordanella floridae) over one complete life cycle.

The acute and chronic effects of endosulfan pulse-exposure on Jordanella floridae (Florida flagfish) over one complete life-cycle.

Comparative embryotoxicity of pulp mill extracts in rainbow trout (Oncorhynchus mykiss), American flagfish (Jordanella floridae) and Japanese medaka (Oryzias latipes).

Effects of pulp and paper mill effluent extracts on liver anaerobic and aerobic metabolic enzymes in rainbow trout.

Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroid levels in juvenile triploid rainbow trout

Aquatic toxicity of pharmaceuticals and personal care products

Canada Research Chair in Aquatic Toxicology

Canada Research Chair in Aquatic Toxicology

Interdisciplinary research using gas chromatography - mass spectrometry

Ecotoxicological biomarker development and validation

Effects of Toxicant Pulse-Exposure on Growth, Survival and Reproduction of Fish

Development of Continuous-flow Wet-laboratory and Controlled Temperature Room Facilities for the Investigation of Pulse-exposure Effects of Contaminants on Aquatic Organisms and Biomarker Validation

Development of continuous-flow wet-laboratory and controlled temperature room facilities for the investigation of pulse-exposure effects of contaminants on aquatic organisms and biomarker validation.

Ecotoxicological impacts of land use on fish communities

Canada Research Chair in Aquatic Toxicology

Frequent collaborators

Andrea Kirkwood

Glen Van Der Kraak

Denina Simmons

Dario Bonetta

Deborah MacLatchy

Glen Van Der Kraak

Chronic effects of hydroxypropyl-β-cyclodextrin on reproduction in the American flagfish (Jordanella floridae) over one complete life cycle.