Faculty profile

Jean-Paul Desaulniers

ResearcherScience, Faculty ofOntario Tech University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Ontario Tech University directory, so their courses may be missing. Find their university profile.

Jean-Paul Desaulniers

Researcher

Science, Faculty of

Ontario Tech University

Oshawa, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
25 publications in the last five years, latest in 2026.
Senior (last) author on 16 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (9 NSERC, 1 SSHRC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

phosphoramidite antisense oligonucleotides azobenzene circular dichroism gene editing nucleic acid chemistry photoresponsive molecules RNA interference

Latest papers

Working So Hard: Double-Stranded RNAs That Can Perform Both Gene Activation and Gene Silencing.
Chembiochem : a European journal of chemical biology · 2026 · senior author
Impact of 2'-fluoro nucleobase modifications on CD detection, sensitivity and specificity of short oligonucleotides bound to alginate hydrogels.
Journal of materials chemistry. B · 2026
Synergistic effects of Fe species distribution and acid site balance in Fe/zeolite catalysts for 5-HMF production from glucose.
RSC advances · 2026

All 48 publications

Latest funding

OUT OF THE MUSEUM AND INTO THE FUTURE: OLIGOSYNTHESIZER REPLACEMENT
NSERC · 2024 · Principal investigator
$150,000
Examining community health by measuring Opioid drug and STBBI prevalence in wastewater across a Public Health Unit in Ontario.
CIHR · 2024 · Co-investigator
$768,825
Synthesis of Folate-Labeled siRNAs (FL-siRNAs) for Specific Tissue Targeting
NSERC · 2023 · Principal investigator
$125,000

All 17 grants and awards

48 publications.

Working So Hard: Double-Stranded RNAs That Can Perform Both Gene Activation and Gene Silencing.

Chiu VW, Hammill ML, Elabed M, Varley S, Lomonosova Y, Hoare J, Voutila J, Hansen H, Koch T, Desaulniers JP

Chembiochem : a European journal of chemical biology2026Senior author

DOI: 10.1002/cbic.70434 PMID: 42376686

Impact of 2'-fluoro nucleobase modifications on CD detection, sensitivity and specificity of short oligonucleotides bound to alginate hydrogels.

Lubrin DK, Elliott CI, Desaulniers JP, Stotesbury T

Journal of materials chemistry. B2026

DOI: 10.1039/d5tb02880a PMID: 42052678

Synergistic effects of Fe species distribution and acid site balance in Fe/zeolite catalysts for 5-HMF production from glucose.

Nanmong T, Obrom W, Yingyuen W, Jaroenchur T, Thamthong P, Wittayakun J, Prayoonpokarach S, Tawachkultanadilok P, Poo-Arporn Y, Wannapaiboon S, Chanlek N, Rungtaweevoranit B, Kosawatthanakun S, Khemthong P, Desaulniers JP, Loiha S

RSC advances2026

DOI: 10.1039/d6ra00413j PMID: 41960297

Exploring Chemically Modified Short Activating RNAs to Increase Stability against Nucleases and Enhance Gene Activation.

Desaulniers JP, Hammill ML, Giorgees I, Chiu VW, Pendergraff H, Aguti S, Voutila J, Hansen H, Habib N, Lomonosova Y, Koch T

Journal of medicinal chemistry2025First author

DOI: 10.1021/acs.jmedchem.5c01648 PMID: 41126696

Variability of Clinical Metrics in Small Population Communities Drive Perceived Wastewater and Environmental Surveillance Data Quality: Ontario, Canada-Wide Study.

Hegazy N, Peng KK, D'Aoust PM, Pisharody L, Mercier E, Ramsay NT, Kabir MP, Nguyen TB, Tomalty E, Addo F, Wong CH, Wan S, Hu J, Dean C, Yang MI, Dhiyebi H, Edwards EA, Servos MR, Ybazeta G, Habash M, Goodridge L, Poon AFY, Arts EJ, Brown S, Payne SJ, Kirkwood A, Simmons DBD, Desaulniers JP, Ormeci B, Kyle C, Bulir D, Charles T, McKay RM, Gilbride KA, Oswald CJ, Peng H, DeGroot C, WSI Consortium, Renouf E, Delatolla R

ACS ES&T water2025

DOI: 10.1021/acsestwater.4c00958 PMID: 40242342

Optimizing RT-qPCR multiplex assays for simultaneous detection of enteric and respiratory viruses in wastewater.

de Melo T, Gedge A, Simmons DBD, Desaulniers JP, Kirkwood AE

Journal of water and health2025

DOI: 10.2166/wh.2025.101 PMID: 40298271

Increased activity of CF3-derivatized levamisole at the ACC-2 receptor from the parasitic nematode Haemonchus contortus.

Collins A, Varley S, Clark T, Chubb N, Forrester S, Desaulniers JP

International journal for parasitology. Drugs and drug resistance2025Senior author

DOI: 10.1016/j.ijpddr.2025.100587 PMID: 40056719

Injection of Ortho-Functionalized Tetrafluorinated Azobenzene-Containing siRNAs into Japanese Medaka Embryos for Photocontrolled Gene Silencing.

Mateus M, Hammill ML, Simmons DBD, Desaulniers JP

Current protocols2024Senior author

DOI: 10.1002/cpz1.70051 PMID: 39546401

In Vivo Injection of Reversible Optically Controlled Short Interfering RNA into Japanese Medaka Embryos (Oryzias latipes) to Regulate Gene Silencing.

Mateus M, Hammill ML, Simmons DBD, Desaulniers JP

ACS chemical biology2024Senior author

DOI: 10.1021/acschembio.4c00290 PMID: 39162696

The role of catchment population size, data normalization, and chronology of public health interventions on wastewater-based COVID-19 viral trends.

Islam G, Gedge A, Ibrahim R, de Melo T, Lara-Jacobo L, Dlugosz T, Kirkwood AE, Simmons D, Desaulniers JP

The Science of the total environment2024Senior author

DOI: 10.1016/j.scitotenv.2024.173272 PMID: 38763190

OUT OF THE MUSEUM AND INTO THE FUTURE: OLIGOSYNTHESIZER REPLACEMENT

Principal investigatorNSERC2024Research Tools and Instruments

Principal investigators: Desaulniers, Jean-Paul

Keywords: Chemical Modification; DNA; Forensic Biomaterials; Gene Silencing; Nucleic Acids; Oligosynthesizer; Organic Chemistry; Phosphoramidite; RNA; Wastewater Detection

$150,000

Examining community health by measuring Opioid drug and STBBI prevalence in wastewater across a Public Health Unit in Ontario.

Co-investigatorCIHR2024Project Grant

Principal investigators: Simmons, Denina D

Keywords: Community Health; Lc-Ms/Ms; Modelling; Opioids; Qpcr; Social Determinants; Stbbis; Wastewater Epidemiology

$768,825

Synthesis of Folate-Labeled siRNAs (FL-siRNAs) for Specific Tissue Targeting

Principal investigatorNSERC2023Idea to Innovation

Principal investigators: Desaulniers, Jean-Paul JPD

Keywords: delivery; folate receptor; folic acid; phosphoramidite; RNA synthesis

$125,000

Multimode microplate reader with imaging for versatile analyses in immunology, microbiology, biochemistry and environmental toxicology

Co-investigatorNSERC2021Research Tools and Instruments

Principal investigators: Green-Johnson, Julia

$137,860

Wastewater epidemiology to measure community gastrointestinal disease

Principal investigatorSSHRC2021New Frontiers in Research Fund - Special Call

Principal investigators: Desaulniers, Jean-Paul

Keywords: RNA oligonucleotides PCR mass spectrometry proteomics wastewater epidemiology

$237,970

Liquid Chromatography High Resolution Tandem Mass Spectrometry for Proteomics, Metabolomics, Epigenetics, and Synthetic Oligonucleotides.

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Simmons, Denina

$150,000

Synthesis and Applications of Chemically-Modified Oligonucleotides

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Desaulniers, Jean-Paul

Keywords: antisense oligonucleotides; azobenzene; circular dichroism; gene editing; nucleic acid chemistry; phosphoramidite; photoresponsive molecules; RNA interference; short interfering RNA; solid-phase synthesis

$174,000

Synthesis of Chemically-Modified Biological Molecules_x000d_

Principal investigatorNSERC2018Collaborative Research and Development Grants

Principal investigators: Desaulniers, Jean-Paul

$52,000

Photoresponsive siRNAs as a biotechnological tool to examine gene function

Principal investigatorNSERC2018Idea to Innovation

Principal investigators: Desaulniers, JeanPaul

$124,450

Synthesis of Novel Sugar-Nucleic Acid Polymers

Principal investigatorNSERC2017Engage Grants Program

Principal investigators: Desaulniers, JeanPaul

$25,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jean-Paul Desaulniers

Research

Latest papers

Latest funding

Working So Hard: Double-Stranded RNAs That Can Perform Both Gene Activation and Gene Silencing.

Impact of 2'-fluoro nucleobase modifications on CD detection, sensitivity and specificity of short oligonucleotides bound to alginate hydrogels.

Synergistic effects of Fe species distribution and acid site balance in Fe/zeolite catalysts for 5-HMF production from glucose.

Exploring Chemically Modified Short Activating RNAs to Increase Stability against Nucleases and Enhance Gene Activation.

Variability of Clinical Metrics in Small Population Communities Drive Perceived Wastewater and Environmental Surveillance Data Quality: Ontario, Canada-Wide Study.

Optimizing RT-qPCR multiplex assays for simultaneous detection of enteric and respiratory viruses in wastewater.

Increased activity of CF3-derivatized levamisole at the ACC-2 receptor from the parasitic nematode Haemonchus contortus.

Injection of Ortho-Functionalized Tetrafluorinated Azobenzene-Containing siRNAs into Japanese Medaka Embryos for Photocontrolled Gene Silencing.

In Vivo Injection of Reversible Optically Controlled Short Interfering RNA into Japanese Medaka Embryos (Oryzias latipes) to Regulate Gene Silencing.

The role of catchment population size, data normalization, and chronology of public health interventions on wastewater-based COVID-19 viral trends.

OUT OF THE MUSEUM AND INTO THE FUTURE: OLIGOSYNTHESIZER REPLACEMENT

Examining community health by measuring Opioid drug and STBBI prevalence in wastewater across a Public Health Unit in Ontario.

Synthesis of Folate-Labeled siRNAs (FL-siRNAs) for Specific Tissue Targeting

Multimode microplate reader with imaging for versatile analyses in immunology, microbiology, biochemistry and environmental toxicology

Wastewater epidemiology to measure community gastrointestinal disease

Liquid Chromatography High Resolution Tandem Mass Spectrometry for Proteomics, Metabolomics, Epigenetics, and Synthetic Oligonucleotides.

Synthesis and Applications of Chemically-Modified Oligonucleotides

Synthesis of Chemically-Modified Biological Molecules_x000d_

Photoresponsive siRNAs as a biotechnological tool to examine gene function

Synthesis of Novel Sugar-Nucleic Acid Polymers

Frequent collaborators

Andrea Kirkwood

Denina Simmons

Lawrence Goodridge

CHRISTOPHER KYLE

Trevor Charles

Robert Delatolla

Banu Ormeci

Hui Peng

Kimberley Gilbride

Christopher DeGroot

Theresa Stotesbury

Sean Forrester

Eric Arts

Claire Oswald

Charmaine Dean

Art Poon

Elizabeth Edwards