Daniel Espiritu, Queen's University

Research

Read how they describe their research on their Queen's University profile.

Latest papers

Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability
Nucleic Acids Research · 2025 · first author
Deciphering Allosteric Modulation of Cancer-Associated Histone Missense Mutations
Journal of Molecular Biology · 2025
Leveraging Gene Redundancy to Find New Histone Drivers in Cancer
Cancers · 2023

4 publications.

01

Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability

Daniel Espiritu, Yiru Sheng, Yunhui Peng, Daria S. Ostroverkhova, Shuxiang Li, David Landsman, Maria J. Aristizabal, Anna R. Panchenko

Nucleic Acids Research20259 citationsFirst authorOpen Access

DOI: 10.1093/nar/gkaf899 PMID: 40966522

02

Deciphering Allosteric Modulation of Cancer-Associated Histone Missense Mutations

Shuxiang Li, Jie Shu, James C Rober, Austin Macklem, Daniel Espiritu, Tanay Debnath, Samuel Tian, Daniel Tian, Maria J. Aristizabal, Anna R. Panchenko

Journal of Molecular Biology20256 citationsOpen Access

DOI: 10.1016/j.jmb.2025.169180 PMID: 40311745

03

Leveraging Gene Redundancy to Find New Histone Drivers in Cancer

Daria Ostroverkhova, Daniel Espiritu, Maria J. Aristizabal, Anna R. Panchenko

Cancers202311 citationsOpen Access

DOI: 10.3390/cancers15133437 PMID: 37444547

04

Molecular Mechanisms of Oncogenesis through the Lens of Nucleosomes and Histones

Daniel Espiritu, Anna K. Gribkova, Shubhangi Gupta, Alexey К. Shaytan, Anna R. Panchenko

The Journal of Physical Chemistry B202134 citationsFirst authorOpen Access

DOI: 10.1021/acs.jpcb.1c00694 PMID: 33769808

Frequent collaborators

Pathology
ANNA
Department of Biology

Co-authors at Queen's University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Maria Aristizabal

Department of Biology

3 shared papers, latest 2025

Shuxiang Li

Pathology

2 shared papers, latest 2025

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Subject: Prospective PhD student Dear Professor Espiritu, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Daniel Espiritu