Ian Chin Sang, Queen's University

Research

C. Elegans Genetics Insulin Signaling Cell Biology Insulin Growth Factors Neurodevelopment Neuropeptides Axon Guidance

Latest papers

An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans.
Peptides · 2021 · senior author
Neuropeptide and microRNA regulators of juvenile hormone production.
General and comparative endocrinology · 2020
C. elegans PTEN and AMPK block neuroblast divisions by inhibiting a BMP-insulin-PP2A-MAPK pathway.
Development (Cambridge, England) · 2018 · senior author

All 8 publications

Latest funding

The role of a kinesin in microRNA regulation during epidermal morphogenesis
NSERC · 2024 · Principal investigator
$47,000
The role of Insulin signaling in neuronal development.
CIHR · 2019 · Nominated PI
$688,500
Neuronal and Epidermal Signaling during C. elegans Morphogenesis
NSERC · 2018 · Principal investigator
$300,000

All 9 grants and awards

8 publications.

01

An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans.

Biglou SG, Bendena WG, Chin-Sang I

Peptides2021Senior author

DOI: 10.1016/j.peptides.2021.170640 PMID: 34450203

02

Neuropeptide and microRNA regulators of juvenile hormone production.

Bendena WG, Hui JHL, Chin-Sang I, Tobe SS

General and comparative endocrinology2020

DOI: 10.1016/j.ygcen.2020.113507 PMID: 32413346

03

C. elegans PTEN and AMPK block neuroblast divisions by inhibiting a BMP-insulin-PP2A-MAPK pathway.

Zheng S, Qu Z, Zanetti M, Lam B, Chin-Sang I

Development (Cambridge, England)2018Senior author

DOI: 10.1242/dev.166876 PMID: 30487179

04

A functional study of all 40 Caenorhabditis elegans insulin-like peptides.

Zheng S, Chiu H, Boudreau J, Papanicolaou T, Bendena W, Chin-Sang I

The Journal of biological chemistry2018Senior author

DOI: 10.1074/jbc.ra118.004542 PMID: 30206121

05

CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis.

Walck-Shannon E, Lucas B, Chin-Sang I, Reiner D, Kumfer K, Cochran H, Bothfeld W, Hardin J

PLoS genetics2016

DOI: 10.1371/journal.pgen.1006415 PMID: 27861585

06

Structures of an Eph receptor tyrosine kinase and its potential activation mechanism.

Wei Q, Liu J, Wang N, Zhang X, Jin J, Chin-Sang I, Zheng J, Jia Z

Acta crystallographica. Section D, Biological crystallography2014

DOI: 10.1107/s1399004714021944 PMID: 25478832

07

The FGLamide-allatostatins influence foraging behavior in Drosophila melanogaster.

Wang C, Chin-Sang I, Bendena WG

PloS one2012

DOI: 10.1371/journal.pone.0036059 PMID: 22558326

08

A role for C. elegans Eph RTK signaling in PTEN regulation.

Brisbin S, Liu J, Boudreau J, Peng J, Evangelista M, Chin-Sang I

Developmental cell2009Senior author

DOI: 10.1016/j.devcel.2009.08.009 PMID: 19853560

The role of a kinesin in microRNA regulation during epidermal morphogenesis

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: CHIN-SANG, IAN

Keywords: kinesin; microrna; morphogenesis; gene regulation; c. elegans; protein-protein interactions; forward genetics; microscopy; rnaseq; cell-cell communication

$47,000

The role of Insulin signaling in neuronal development.

Nominated PICIHR2019Project Grant

Principal investigators: Chin Sang, Ian D

Keywords: C. Elegans; Cell Biology; Genetics; Insulin Growth Factors; Insulin Signaling; Neurodevelopment; Neuropeptides

$688,500

Neuronal and Epidermal Signaling during C. elegans Morphogenesis

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: CHINSANG, IAN

$300,000

Accelerating biology research with a bench-top next-generation sequencer

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Eckert, Christopher

$149,460

The Role of Eph and Insulin Receptor Tyrosine Kinase Signaling in C. elegans Neurodevelopment

Nominated PICIHR2013Operating Grant

Principal investigators: Chin Sang, Ian D

Keywords: Axon Guidance; C. Elegans; Cancer; Cell Migration; Eph Receptor Tyrosine Kinase; Genetics; Insulin Signaling; Morphogenesis; Pten; Signal Transduction

$619,296

Identification and Characterization of Genes that Regulate Morphogenesis

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: ChinSang, Ian

$332,500

Identification and Characterization of Genes that Regulate Morphogenesis

Principal investigatorNSERC2013Discovery Grants Program - Accelerator Supplements

Principal investigators: ChinSang, Ian

$120,000

Genetics and molecular biology of morphogenesis

Principal investigatorNSERC2008Discovery Grants Program - Individual

Principal investigators: ChinSang, Ian

$150,000

Molecular genetics of C. elegans morphogenesis

Principal investigatorNSERC2003Discovery Grants Program - Individual

Principal investigators: ChinSang, Ian

$148,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Zongchao Jia

Faculty

1 shared papers, latest 2014

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2024

Subject: Prospective PhD student: C. Elegans Dear Professor Chin Sang, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans." (2021), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "The role of a kinesin in microRNA regulation during epidermal morphogenesis" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]