Yuliya Knyahnytska, Queen's University

Research

Read how they describe their research on their Queen's University profile.

Latest papers

Confirmatory efficacy and safety trial of magnetic seizure therapy versus right unilateral ultra-brief electroconvulsive therapy in depression (CREST-MST): a randomised, double-blind, non-inferiority trial in Canada and the USA.
The lancet. Psychiatry · 2026
Identifying clinical markers of bipolar disorder in a depressed outpatient sample: A tertiary clinic comparison with major depressive disorder.
Journal of affective disorders · 2026
Efficacy and safety of ketamine maintenance therapy in treatment-resistant depression: A systematic review of treatment protocols and clinical outcomes.
Journal of affective disorders · 2026 · senior author

All 4 publications

Latest funding

Electroencephalography-Based Prediction of Clinical Response to Deep Transcranial Magnetic Stimulation in Comorbid Depression and Post-Traumatic Stress Disorder
CIHR · 2025 · Co-investigator
$979,965
Brain-Oscillation Synchronized Stimulation of the Dorsomedial Prefrontal Cortex: A Precision Medicine Treatment for Obsessive Compulsive Disorder
CIHR · 2022 · Co-investigator
$535,501
Theta-burst stimulation for bipolar depression: A randomized controlled trial
CIHR · 2022 · Co-investigator
$520,200

All 6 grants and awards

4 publications.

01

Confirmatory efficacy and safety trial of magnetic seizure therapy versus right unilateral ultra-brief electroconvulsive therapy in depression (CREST-MST): a randomised, double-blind, non-inferiority trial in Canada and the USA.

Blumberger DM, McClintock SM, Thorpe KE, Tamminga CA, Foley K, Husain MM, Kaster TS, Knyahnytska Y, Voineskos D, Bailey KJ, Hubregsen JJ, Weissman CR, Daskalakis ZJ

The lancet. Psychiatry20267 citationsOpen Access

DOI: 10.1016/s2215-0366(26)00060-x PMID: 41997695

02

Identifying clinical markers of bipolar disorder in a depressed outpatient sample: A tertiary clinic comparison with major depressive disorder.

Cabrera-Abreu C, Alzbeidi N, Avila C, Hernandorena C, Kolar D, Milev R, Ruzica J, Knyahnytska Y, Vazquez G

Journal of affective disorders20261 citations

DOI: 10.1016/j.jad.2025.120612 PMID: 41197913

03

Efficacy and safety of ketamine maintenance therapy in treatment-resistant depression: A systematic review of treatment protocols and clinical outcomes.

Al-Garni AM, Vazquez G, Alotibi T, Hernandorena C, Knyahnytska Y

Journal of affective disorders2026Senior author

DOI: 10.1016/j.jad.2025.120475 PMID: 41109417

04

Extended course accelerated intermittent theta burst stimulation as a substitute for depressed patients needing electroconvulsive therapy.

Goodman MS, Trevizol AP, Konstantinou GN, Boivin-Lafleur D, Brender R, Downar J, Kaster TS, Knyahnytska Y, Vila-Rodriguez F, Voineskos D, Daskalakis ZJ, Blumberger DM

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20257 citationsOpen Access

DOI: 10.1038/s41386-024-02007-w PMID: 39443721

Electroencephalography-Based Prediction of Clinical Response to Deep Transcranial Magnetic Stimulation in Comorbid Depression and Post-Traumatic Stress Disorder

Co-investigatorCIHR2025Project Grant

Principal investigators: Farzan, Faranak

Keywords: Biomarkers; Deep Transcranial Magnetic Stimulation; Depression; Electroencephalography; Ptsd; Response Prediction

$979,965

Brain-Oscillation Synchronized Stimulation of the Dorsomedial Prefrontal Cortex: A Precision Medicine Treatment for Obsessive Compulsive Disorder

Co-investigatorCIHR2022Project Grant

Principal investigators: Zrenner, Brigitte; Blumberger, Daniel M; Griffiths, John D; Zrenner, Christoph D

Keywords: Eeg; Non-Invasive Brain Intervention; Ocd; Personalized Medicine; Pilot Clinical Study; Tms; Treatment

$535,501

Theta-burst stimulation for bipolar depression: A randomized controlled trial

Co-investigatorCIHR2022Project Grant

Principal investigators: Kaster, Tyler; Voineskos, Daphne

Keywords: Bipolar Depression; Efficacy; Randomized Controled Trial; Repetitive Transcranial Magnetic Stimulation; Safety

$520,200

Developing, administering, and evaluating online psychotherapy and psychoeducation programs to address common mental health challenges faced by post-secondary students in Kingston, Frontenac, Lennox & Addington (KFL&A)

Co-investigatorCIHR2021Team Grant: HCIS - LOI - Healthcare systems, services and policies

Principal investigators: Alavi, Nazanin; Soares, Claudio D; Milev, Roumen V

Keywords: Accessible Mental Health Care; Borderline Personality; Cognitive Behavioural Therapy; Diet And Exercise; Electronic Mental Health Care; Mental Health Disorders; Mood And Anxiety Disorders; Psychoeducation; Psychotherapy; Substance Abuse

$25,000

Delivering online cognitive behavioural therapy (iCBT) to address mental health challenges in correctional officers and other public safety personnel

Co-investigatorCIHR2019Team Grant: Mental Wellness in Public Safety Team Grants - LOI

Principal investigators: Alavi, Nazanin

Keywords: Cognitive Behavioural Therapy (Cbt); Correctional Officers; Digital Health; Icbt; Mental Health; Online Delivery; Public Safety Personnel (Psp)

$30,000

Delivering online cognitive behavioural therapy (iCBT) to address mental health challenges in correctional officers and other public safety personnel

Co-investigatorCIHR2019Team Grant: Mental Wellness in Public Safety Team Grants

Principal investigators: Alavi, Nazanin; Simpson, Alexander I

Keywords: Accessibility; Anxiety; Cognitive Behavioral Therapy (Cbt); Correctional Services; Depression; Icbt; Online Care; Ptsd; Public Safety Personnel

$860,000

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Department of Psychiatry
Department of Anesthesiology and Pain Medicine
Other

Applying for

Paper to mention

Subject: Prospective PhD student Dear Professor Knyahnytska, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Confirmatory efficacy and safety trial of magnetic seizure therapy versus right unilateral ultra-brief electroconvulsive therapy in depression (CREST-MST): a randomised, double-blind, non-inferiority trial in Canada and the USA." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]