Mark Towler, Toronto Metropolitan University

Research

Glass Polyalkenoate Cement Sternal Fixation Sternotomy Bioactivity Hemorrhage Mesoporous Glass Bioglass Cone Augments

Latest papers

Partial coverage adhesive augmented sternal fixation and stabilization: A biomechanical analysis.
Journal of biomechanics · 2024 · senior author
Porcine liver injury model to assess tantalum-containing bioactive glass powders for hemostasis.
Journal of materials science. Materials in medicine · 2022 · senior author
Review of Biomechanical Studies and Finite Element Modeling of Sternal Closure Using Bio-Active Adhesives.
Bioengineering (Basel, Switzerland) · 2022 · senior author

All 10 publications

Latest funding

L2M NSERC - Novel Glass Polyalkenoate Cement for the Treatment of Metastatic Bone Cancer.
NSERC · 2022 · Principal investigator
$20,000
Inductively Coupled Plasma - Optical Emission Spectroscopy Requisition
NSERC · 2019 · Principal investigator
$77,047
Structure-property relationships in ionically substituted bioactive glasses.
NSERC · 2019 · Principal investigator
$156,000

All 15 grants and awards

10 publications.

01

Partial coverage adhesive augmented sternal fixation and stabilization: A biomechanical analysis.

Deignan E, Alabassi A, Brandon S, Papini M, Hurtig M, Towler M

Journal of biomechanics2024Senior author

DOI: 10.1016/j.jbiomech.2024.112374 PMID: 39509808

02

Porcine liver injury model to assess tantalum-containing bioactive glass powders for hemostasis.

Nagrath M, Bince D, Rowsell C, Polintan D, Rezende-Neto J, Towler M

Journal of materials science. Materials in medicine2022Senior author

DOI: 10.1007/s10856-022-06674-3 PMID: 35670885

03

Review of Biomechanical Studies and Finite Element Modeling of Sternal Closure Using Bio-Active Adhesives.

Al-Abassi A, Papini M, Towler M

Bioengineering (Basel, Switzerland)2022Senior author

DOI: 10.3390/bioengineering9050198 PMID: 35621476

04

In vitro immunomodulatory effects of novel strontium and zinc-containing GPCs.

Marx D, Papini M, Towler M

Bio-medical materials and engineering2022Senior author

DOI: 10.3233/bme-211346 PMID: 35180104

05

In vitro osteogenic performance of two novel strontium and zinc-containing glass polyalkenoate cements.

Marx D, Yazdi AR, Papini M, Towler M

Journal of biomedical materials research. Part A2021Senior author

DOI: 10.1002/jbm.a.37127 PMID: 33125181

06

A review of the latest insights into the mechanism of action of strontium in bone.

Marx D, Rahimnejad Yazdi A, Papini M, Towler M

Bone reports2020Senior author

DOI: 10.1016/j.bonr.2020.100273 PMID: 32395571

07

Raman spectroscopy as a predictive tool for monitoring osteoporosis therapy in a rat model of postmenopausal osteoporosis.

Beattie JR, Sophocleous A, Caraher MC, O'Driscoll O, Cummins NM, Bell SEJ, Towler M, Rahimnejad Yazdi A, Ralston SH, Idris AI

Journal of materials science. Materials in medicine2019

DOI: 10.1007/s10856-019-6226-x PMID: 30747334

08

Raman spectroscopy predicts the link between claw keratin and bone collagen structure in a rodent model of oestrogen deficiency.

Caraher MC, Sophocleous A, Beattie JR, O'Driscoll O, Cummins NM, Brennan O, O'Brien FJ, Ralston SH, Bell SEJ, Towler M, Idris AI

Biochimica et biophysica acta. Molecular basis of disease2018

DOI: 10.1016/j.bbadis.2017.10.020 PMID: 29066282

09

Percutaneous upper extremity fracture fixation using a novel glass-based adhesive

Zalzal P, Safir O, Alhalawani A, Papini M, Towler M

Journal of Orthopaedics20189 citationsSenior author

DOI: 10.1016/j.jor.2018.01.033

10

Comparative study of Weibull characteristic strength and mean strength of GPCs to confirm the minimum number of samples needed for confident strength reporting.

Mehrvar C, Curran DJ, Alhalawani AM, Boyd D, Towler M

Journal of the mechanical behavior of biomedical materials2015Senior author

DOI: 10.1016/j.jmbbm.2014.12.008 PMID: 25553555

L2M NSERC - Novel Glass Polyalkenoate Cement for the Treatment of Metastatic Bone Cancer.

Principal investigatorNSERC2022Idea to Innovation

Principal investigators: Towler, Mark MR

$20,000

Inductively Coupled Plasma - Optical Emission Spectroscopy Requisition

Principal investigatorNSERC2019Research Tools and Instruments

Principal investigators: Towler, Mark

$77,047

Structure-property relationships in ionically substituted bioactive glasses.

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Towler, Mark

$156,000

CREATE: Industry-Ready talent for Canadian MedTech

Co-investigatorNSERC2019Collaborative Research and Training Experience

Principal investigators: Waldman, Stephen

$1,649,500

Optimization of a device for the storage, mixing and delivery of sterilized bone adhesive

Principal investigatorNSERC2018Idea to Innovation

Principal investigators: Towler, Mark

$119,950

Development of a Proprietary, Glass-Based Adhesive for Sternal Fixation and Stabilisation.

Nominated PICIHR2018Project Grant

Principal investigators: Towler, Mark R

Keywords: Glass Polyalkenoate Cement; Sternal Fixation; Sternotomy

$602,438

Spark Optical Emission Spectrometer for Composition Determination

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Ravindran, Comondore

$56,992

Synthesis of Bioactive Augments for use in Revision Knee Joint Replacement

Principal investigatorNSERC2016Collaborative Health Research Projects

Principal investigators: Towler, Mark

$250,862

A novel approach to treating hemorrhage with mesoporous bioactive glasses.

Nominated PICIHR2016Project Grant

Principal investigators: Towler, Mark R

Keywords: Bioactivity; Hemorrhage; Mesoporous Glass

$359,315

Synthesis of Bioactive Augments for use in Revision Knee Joint Replacement

Nominated PICIHR2015Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Towler, Mark R; Schemitsch, Emil H

Keywords: Bioglass; Cone Augments; Orthopedic Surgery

$250,861

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Mechanical and Industrial Engineering
Applied Oral Sciences
Surgery

Co-authors at Toronto Metropolitan University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Daniel Boyd

Applied Oral Sciences

1 shared papers, latest 2015

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2022

Subject: Prospective PhD student: Glass Polyalkenoate Cement Dear Professor Towler, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Partial coverage adhesive augmented sternal fixation and stabilization: A biomechanical analysis." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "L2M NSERC - Novel Glass Polyalkenoate Cement for the Treatment of Metastatic Bone Cancer." (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Mark Towler

Research

Latest papers

Latest funding

Partial coverage adhesive augmented sternal fixation and stabilization: A biomechanical analysis.

Porcine liver injury model to assess tantalum-containing bioactive glass powders for hemostasis.

Review of Biomechanical Studies and Finite Element Modeling of Sternal Closure Using Bio-Active Adhesives.

In vitro immunomodulatory effects of novel strontium and zinc-containing GPCs.

In vitro osteogenic performance of two novel strontium and zinc-containing glass polyalkenoate cements.

A review of the latest insights into the mechanism of action of strontium in bone.

Raman spectroscopy as a predictive tool for monitoring osteoporosis therapy in a rat model of postmenopausal osteoporosis.

Raman spectroscopy predicts the link between claw keratin and bone collagen structure in a rodent model of oestrogen deficiency.

Percutaneous upper extremity fracture fixation using a novel glass-based adhesive

Comparative study of Weibull characteristic strength and mean strength of GPCs to confirm the minimum number of samples needed for confident strength reporting.

L2M NSERC - Novel Glass Polyalkenoate Cement for the Treatment of Metastatic Bone Cancer.

Inductively Coupled Plasma - Optical Emission Spectroscopy Requisition

Structure-property relationships in ionically substituted bioactive glasses.

CREATE: Industry-Ready talent for Canadian MedTech

Optimization of a device for the storage, mixing and delivery of sterilized bone adhesive

Development of a Proprietary, Glass-Based Adhesive for Sternal Fixation and Stabilisation.

Spark Optical Emission Spectrometer for Composition Determination

Synthesis of Bioactive Augments for use in Revision Knee Joint Replacement

A novel approach to treating hemorrhage with mesoporous bioactive glasses.

Synthesis of Bioactive Augments for use in Revision Knee Joint Replacement

Frequent collaborators

Paul Zalzal

Daniel Boyd