Faculty profile
Melanie Alpaugh
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Read how they describe their research on their University of Guelph profile.
Latest papers
The impact of tau deletion on Huntington's disease: An in vivo perspective.
Molecular therapy : the journal of the American Society of Gene Therapy · 2026
Dietary nitrate and resveratrol co-supplementation prevent HFD-mediated impairments in carotid blood flow and behavioral parameters in male mice.
Physiological reports · 2026
Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration.
Fluids and barriers of the CNS · 2025
Latest funding
- $79,429
Understanding the interactions between hypertension and Huntington's disease
ONTARIO · 2025 · Principal investigator
- $150,000
Advanced High-Resolution Imaging for Muscle and Brain Research
NSERC · 2025 · Co-investigator
- $79,429
Understanding the interactions between hypertension and Huntington's disease
CFI · 2024 · Principal investigator
6 publications.
The impact of tau deletion on Huntington's disease: An in vivo perspective.
Lepinay E, Saint-Pierre M, Teixeira M, Snapyan M, Oueslati A, Parent M, Alpaugh M, Cicchetti F
Dietary nitrate and resveratrol co-supplementation prevent HFD-mediated impairments in carotid blood flow and behavioral parameters in male mice.
DesOrmeaux GJ, Dowling JL, Barbeau PA, Handy RM, Alpaugh M, Holloway GP
Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration.
Denis HL, de Rus Jacquet A, Alpaugh M, Panisset M, Barker RA, Boilard É, Cicchetti F
Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.
Alpaugh M, Lantero-Rodriguez J, Benedet AL, Manseau U, Boutin M, Maiuri M, Denis HL, Masnata M, Fazal SV, Chouinard S, Rosa-Neto P, Barker RA, Blennow K, Zetterberg H, Labib R, Cicchetti F
Investigating the Interplay between Cardiovascular and Neurodegenerative Disease.
Cousineau JP, Dawe AM, Alpaugh M
Plasma GFAP and its association with disease severity in Huntington's disease.
Tan K, Alpaugh M, Ashton NJ, Chouinard S, Barker RA, Blennow K, Zetterberg H, Cicchetti F, Benedet AL
Understanding the interactions between hypertension and Huntington's disease
Principal investigators: Alpaugh, Melanie
Keywords: Cell culture, blood-brain barrier modeling, human induced pluripotent stem cells, Huntington's disease, cardiovascular disease.
Advanced High-Resolution Imaging for Muscle and Brain Research
Principal investigators: Simpson, Jeremy
Keywords: cardiac physiology; cardiogenesis; advanced non-invasive imaging; integrative mammalian physiology; sex differences; hqp training; metabolism; endocrine; heart-brain interactions; mitochondria
Understanding the interactions between hypertension and Huntington's disease
Principal investigators: Alpaugh, Melanie
Keywords: cell culture, blood-brain barrier modeling, human induced pluripotent stem cells In vitro, Sample processing and assessment, Animal behaviour, Imaging and analys
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Francesca Cicchetti and Abid Oueslati: 11 shared papers
- Francesca Cicchetti and Martin Parent: 4 shared papers
- Francesca Cicchetti and Melanie Alpaugh: 4 shared papers
- Martin Parent and Abid Oueslati: 2 shared papers
- Francesca Cicchetti and Pedro Rosa-Neto: 1 shared paper
- Martin Parent and Melanie Alpaugh: 1 shared paper
- Pedro Rosa-Neto and Melanie Alpaugh: 1 shared paper
- Abid Oueslati and Melanie Alpaugh: 1 shared paper
- Department of Molecular & Cellular Biology
- Médecine moléculaire
- Psychiatrie et neurosciences
- Department of Neurology and Neurosurgery
- Other
Co-authors at University of Guelph, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on September 27, 2026 from the university directory, publication records and public research funding records.