Alexandre Stewart

Research

Read how they describe their research on their University of Ottawa profile.

Arterial Calcification Arterial Smooth Muscle Cells Bone Morphogenic Protein Crispr/Cas9 Technology Genetic Association Study Human Ipsc Innate Immune Mechanisms Mouse Genetic Models

Latest papers

Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial
The Lancet · 2012
A common allele on chromosome 9 associated with coronary heart disease.
Science (New York, N.Y.) · 2007

All 2 publications

Latest funding

Genetic mechanisms of coronary artery calcification: focus on IRF2BP2
CIHR · 2023 · Nominated PI
$1,025,100
Innate immune mechanisms coordinating hepatic metabolic homeostasis
NSERC · 2016 · Principal investigator
$186,000
Genetic mechanisms of arterial calcification
CIHR · 2016 · Nominated PI
$554,625

All 8 grants and awards

2 publications.

01

Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial

Roberts JD, Wells GA, Le May MR, Labinaz M, Glover C, Froeschl M, Dick A, Marquis J-F, O'Brien E, Goncalves S

The Lancet2012369 citations

DOI: 10.1016/s0140-6736(12)60161-5

02

A common allele on chromosome 9 associated with coronary heart disease.

McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, Hinds DA, Pennacchio LA, Tybjaerg-Hansen A, Folsom AR, Boerwinkle E, Hobbs HH, Cohen JC

Science (New York, N.Y.)2007

DOI: 10.1126/science.1142447 PMID: 17478681

Genetic mechanisms of coronary artery calcification: focus on IRF2BP2

Nominated PICIHR2023Project Grant

Principal investigators: Stewart, Alexandre F; Stanford, William L

Keywords: Arterial Calcification; Arterial Smooth Muscle Cells; Bone Morphogenic Protein; Crispr/Cas9 Technology; Genetic Association Study; Human Ipsc; Innate Immune Mechanisms; Mouse Genetic Models; Runx2; Sex Differences

$1,025,100

Innate immune mechanisms coordinating hepatic metabolic homeostasis

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Stewart, Alexandre

$186,000

Genetic mechanisms of arterial calcification

Nominated PICIHR2016Project Grant

Principal investigators: Stewart, Alexandre F

Keywords: Arterial Calcification; Arterial Smooth Muscle Cells; Atherosclerosis; Ct Angiography; Elilsa; Genetics; Human Studies; Macrophages; Population Study; Statherin

$554,625

How a Novel Innate Immune Regulatory Factor Affects Liver Cholesterol and Triglyceride Homeostasis

SupervisorCIHR2014CIHR Fellowship

Principal investigators: Huang, Hua

Keywords: Cholesterol And Triglyceride Metabolism; Gwas; Hepatitis; Interferon Regulatory Factors; Irf2bp2; Steatosis; Transcription & Gene Regulation; Transgenic Mouse Model

$135,000

Statistical methods of estimating genetic associations of low detectability

Co-investigatorCIHR2012Operating Grant

Principal investigators: Bickel, David R

Keywords: Bayesian Inference; Biostatistics; Empirical Bayes; Genetic Epidemiology; Genome-Wide Association Study; Imprecise Probability; Large-Scale Inference; Local False Discovery Rate; Robust Bayesian; Statistical Genetics

$222,083

Reassessment of anti-platelet therapy using individualized strategies - Association of genetic variants to adverse outcomes in clopidogrel treated patients after percutaneous coronary intervention: the RAPID AGAP study

Principal investigatorCIHR2011Operating Grant

Principal investigators: So, Derek Y; Stewart, Alexandre F

Keywords: Clopidogrel Resistance; Cyp2c19; Genetic Variants; Percutaneous Coronary Intervention; Pon-1

$76,244

Translational derepression during ischemia

Nominated PICIHR2011Operating Grant

Principal investigators: Stewart, Alexandre F

Keywords: Cell Culture; Hypoxia; Ischemia; Molecular Biology; Rna Binding Protein; Transgenic Mice; Translation Derepression; Vascularization

$300,118

Control of skeletal muscle differentiation and regeneration

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Stewart, Alexandre

$135,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Medicine
Medicine

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Chris Glover

Department of Medicine

1 shared papers, latest 2012

Marino Labinaz

Department of Medicine

1 shared papers, latest 2012

Jason Roberts

Medicine

1 shared papers, latest 2012

Ruth McPherson

Medicine

1 shared papers, latest 2007

Write to this professor

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Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Arterial Calcification Dear Professor Stewart, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial" (2012), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Genetic mechanisms of coronary artery calcification: focus on IRF2BP2" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]