Faculty profile
Armen Saghatelyan
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Research
Latest papers
Cilia beating of ependymal cells regulates adult neural stem cell quiescence via mechanical forces mediated by PKD1/2-TRPM3.
Neuron · 2026 · senior author
Autophagy Is Required for Dopaminergic Axon Development and Confers Their Responsiveness to Guidance Cues.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.
NPJ Parkinson's disease · 2025
Latest funding
- $1,293,616
The brain circuitry regulating the generation and cilia beating of ependymal cells
CIHR · 2026 · Nominated PI
- $120,000
The Neuroimmune Connection: Olfactory Bulb Microglial Activation in Parkinson's Disease
CIHR · 2025 · Supervisor
- $87,000
Functional interrogation and behavioral implication of olfactory bulb interneurons born at distinct developmental stages.
NSERC · 2024 · Principal investigator
9 publications.
Cilia beating of ependymal cells regulates adult neural stem cell quiescence via mechanical forces mediated by PKD1/2-TRPM3.
Bressan C, Gengatharan A, Rodriguez-Aller R, Richter ML, Snapyan M, Fischer-Sternjak J, Roukerd MR, Rosin N, Cherinet A, Biernaskie J, Habibi E, Götz M, Saghatelyan A
Autophagy Is Required for Dopaminergic Axon Development and Confers Their Responsiveness to Guidance Cues.
Schaan Profes M, Gora C, Lavoie-Cardinal F, Saghatelyan A, Lévesque M
Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.
Rodriguez-Aller R, Romero-Quineche B, Morissette M, Sheta R, Di Paolo T, Saghatelyan A, Oueslati A
Distinct Ultrastructural Properties and Plasticity of Synapses Formed by Adult-Born and Early-Born Interneurons in the Mouse Olfactory Bulb.
Snapyan M, Constantinescu VS, Saghatelyan A, Parent M
Adult Neurogenesis in the Subventricular Zone of Patients with Huntington's and Parkinson's Diseases and following Long-Term Treatment with Deep Brain Stimulation.
Snapyan M, Desmeules F, Munro J, Bérard M, Saikali S, Gould PV, Richer M, Pourcher E, Langlois M, Dufresne AM, Prud'homme M, Cantin L, Parent A, Saghatelyan A, Parent M
Neural stem cell quiescence and activation dynamics are regulated by feedback input from their progeny under homeostatic and regenerative conditions.
Marymonchyk A, Rodriguez-Aller R, Willis A, Beaupré F, Warsi S, Snapyan M, Clavet-Fournier V, Lavoie-Cardinal F, Kaplan DR, Miller FD, Saghatelyan A
Calretinin-Expressing Neurons in the Basal Forebrain Specifically Contact Granule Cells in the Olfactory Bulb and Modulate Odor Learning.
Constantinescu VS, Folschweiller S, Siri T, Alonso M, De Saint Jan D, Saghatelyan A
Distinct forms of structural plasticity of adult-born interneuron spines in the mouse olfactory bulb induced by different odor learning paradigms.
Ferreira A, Constantinescu VS, Malvaut S, Saghatelyan A, Hardy SV
Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia.
Bressan C, Snapyan M, Snapyan M, Klaus J, di Matteo F, Robertson SP, Treutlein B, Parent M, Cappello S, Saghatelyan A
The brain circuitry regulating the generation and cilia beating of ependymal cells
Principal investigators: Saghatelyan, Armen
Keywords: Aging; Basal Forebrain (Bf); Cilia Beating; Ependymal Cells; Horizontal Limb Of Diagonal Band (Hdb); In Vivo Mini-Endoscopic Imaging; Neural Stem Cells (Nscs); Optogenetics; Trans-Synaptic Tracing
The Neuroimmune Connection: Olfactory Bulb Microglial Activation in Parkinson's Disease
Principal investigators: Selitser, Maya
Keywords: Bioluminescence Imaging; Calcium Imaging; Hyposmia; Microglia; Neurodegeneration; Neuroinflammation; Olfaction; Olfactory Bulb; Parkinson'S Disease
Functional interrogation and behavioral implication of olfactory bulb interneurons born at distinct developmental stages.
Principal investigators: Saghatelyan, Armen
Keywords: adult neurogenesis; olfactory bulb; olfaction; early-born and adult-born neurons; morpho-functional plasticity; in vivo two-photon imaging; optogenetics; electrophysiology; odor stimulation; odor behavior
Integration and decoding of micro-environmental signals in neural stem cells
Principal investigators: Saghatelyan, Armen
Keywords: Adult Proliferative Stem Cell; Adult Quiescent Stem Cell; Ca2+ Imaging; Crispr-Cas9; Freely Behaving Animals; In Vivo Imaging; Micro-Environmental Factors; Mini-Endoscopic Imaging; Neural Stem Cell; Vasculature
Canada Research Chair - Tier 1
Principal investigators: Saghatelyan, Armen
Keywords: Crc
The involvement of different brain regions in odor processing
Principal investigators: Saghatelyan, Armen
Keywords: Mini-Endoscopic Imaging; Mouse; Odor Behavior; Odor Processing; Olfaction; Olfactory Bulb; Optogenetics; Patch-Clamp; Trans-Synaptic Viral Mapping; Two-Photon Imaging
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Cellular and Molecular Medicine
- Psychiatrie
- Psychiatrie et de neurosciences
- Other
Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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