Faculty profile
Pierre Mattar
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Read how they describe their research on their University of Ottawa profile.
Latest papers
Neocortical neurogenesis: a proneural gene perspective.
The FEBS journal · 2025
Chd4 remodels chromatin to control retinal cell type specification and lineage termination.
Development (Cambridge, England) · 2025 · senior author
Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome.
Human molecular genetics · 2023 · senior author
Latest funding
- $100,000
Dissecting the role of chromatin remodelling in neocortical neurogenesis and neurodevelopmental disorders
CIHR · 2024 · Nominated PI
- $180,000
Interrogating the Role of Chromatin Remodelling Proteins in Vision Health and Development using Mouse Models of Neurological System Diseases to Devise Novel Therapeutic Approaches for Visual Impairment
CIHR · 2023 · Supervisor
- $8,000,000
A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders
SSHRC · 2022 · Co-investigator
8 publications.
Neocortical neurogenesis: a proneural gene perspective.
Vasan L, Moffat A, Mattar P, Schuurmans C
Chd4 remodels chromatin to control retinal cell type specification and lineage termination.
Shah S, Medisetti S, Fernandes JAL, Mattar P
Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome.
Larrigan S, Joshi SV, Mattar P
Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration.
Herrera I, Fernandes JAL, Shir-Mohammadi K, Levesque J, Mattar P
Direct neuronal reprogramming by temporal identity factors.
Boudreau-Pinsonneault C, David LA, Lourenço Fernandes JA, Javed A, Fries M, Mattar P, Cayouette M
GliaMorph: a modular image analysis toolkit to quantify Müller glial cell morphology.
Kugler E, Bravo I, Durmishi X, Marcotti S, Beqiri S, Carrington A, Stramer B, Mattar P, MacDonald RB
Chromatin Remodeling in the Brain-a NuRDevelopmental Odyssey.
Larrigan S, Shah S, Fernandes A, Mattar P
A Casz1-NuRD complex regulates temporal identity transitions in neural progenitors.
Mattar P, Jolicoeur C, Dang T, Shah S, Clark BS, Cayouette M
Dissecting the role of chromatin remodelling in neocortical neurogenesis and neurodevelopmental disorders
Principal investigators: Mattar, Pierre Adel
Keywords: Autism Spectrum Disorder; Development; Intellectual Disability; Neocortex; Neurodevelopmental Disorders; Neurogenesis
Interrogating the Role of Chromatin Remodelling Proteins in Vision Health and Development using Mouse Models of Neurological System Diseases to Devise Novel Therapeutic Approaches for Visual Impairment
Principal investigators: Lagali, Pamela S
Keywords: Chromatin Remodelling; Epigenetics; Gene; Gene Expression; Mouse Models; Neurodevelopment; Neuroprotection; Photoreceptors; Retinal Degeneration; Retinal Development
A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders
Principal investigators: Schuurmans, Carol
Keywords: neurodegenerative disease,; Alzheimer's disease; direct neuronal reprogramming; transcription factors; gene regulatory networks ; computer-guided design; nanoparticles; epigenomics ; neurological disorders; self-amplifying RNA; bacteriophage; astrocytes; stroke; epilepsy; focused ultrasound
Molecular mechanisms controlling photoreceptor genome organization and neurodegeneration
Principal investigators: Mattar, Pierre Adel
Keywords: Epigenetics; Heterochromatin; Lamina; Nucleus; Photoreceptor; Polycomb; Retina; Transcription
Molecular dissection of temporal competence in neural progenitors
Principal investigators: Mattar, Pierre Adel
Keywords: Chromatin; Development; Developmental Timing; Epigenetics; Gliogenesis; Neurogenesis; Retina; Transcription
Molecular control of genome architecture
Principal investigators: Nad, Ivana
Keywords: Atac-Seq; Chromatin; Cloning; Confocal Microscpy; Electroporation; Genome; Genomics; Lamina; Retina; Rna-Seq
Molecular mechanisms regulating temporal identity in neural progenitors
Principal investigators: Cayouette, Michel
Keywords: Epigenetic; Gene Expression; Genome Organization; Neurogenesis; Polycomb; Temporal Patterning; Transcription Factor
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Michel Cayouette and Pierre Mattar: 2 shared papers
- Michel Cayouette and Carol Schuurmans: 1 shared paper
- Carol Schuurmans and Pierre Mattar: 1 shared paper
- Cellular and Molecular Medicine
- Other
Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.