Shawn Beug, University of Ottawa

Research

Crc Biomarkers Cancer Glioblastoma Immune Checkpoint Inhibitor Immunotherapy Inhibitors Of Apoptosis (Iap)Programmed Cell Death 1 (Pd-1)

Latest papers

Sortilin regulates sorting and secretion of Sonic hedgehog.
Journal of cell science · 2016
Expression profiles of elastase1 (NvElastaseI) and secretory leukocyte protease inhibitor (NvSLPI) during forelimb regeneration in adult Notophthalmus viridescens suggest a role in epithelial remodeling and delamination.
Development genes and evolution · 2006
Newt orthologue of Growth arrest-specific 6 (NvGas6) is implicated in stress response during newt forelimb regeneration.
Developmental dynamics : an official publication of the American Association of Anatomists · 2006 · first author

All 4 publications

Latest funding

Unlocking T cell therapy for pediatric brain tumors
CIHR · 2026 · Nominated PI
$1,181,926
Small molecule enhancement of immune cell function to drive anti-cancer responses
CIHR · 2026 · Nominated PI
$1,178,100
Canada Research Chair - Tier 2
CIHR · 2025 · Nominated PI
$500,000

All 12 grants and awards

4 publications.

01

Sortilin regulates sorting and secretion of Sonic hedgehog.

Campbell C, Beug S, Nickerson PE, Peng J, Mazerolle C, Bassett EA, Ringuette R, Jama FA, Morales C, Christ A, Wallace VA

Journal of cell science2016

DOI: 10.1242/jcs.183541 PMID: 27632999

02

Expression profiles of elastase1 (NvElastaseI) and secretory leukocyte protease inhibitor (NvSLPI) during forelimb regeneration in adult Notophthalmus viridescens suggest a role in epithelial remodeling and delamination.

Vascotto SG, Beug S, Liversage RA, Tsilfidis C

Development genes and evolution2006

DOI: 10.1007/s00427-006-0061-z PMID: 16508785

03

Newt orthologue of Growth arrest-specific 6 (NvGas6) is implicated in stress response during newt forelimb regeneration.

Beug S, Vascotto SG, Tsilfidis C

Developmental dynamics : an official publication of the American Association of Anatomists2006First author

DOI: 10.1002/dvdy.20690 PMID: 16444701

04

Identification of cDNAs associated with late dedifferentiation in adult newt forelimb regeneration.

Vascotto SG, Beug S, Liversage RA, Tsilfidis C

Developmental dynamics : an official publication of the American Association of Anatomists2005

DOI: 10.1002/dvdy.20304 PMID: 15789445

Unlocking T cell therapy for pediatric brain tumors

Nominated PICIHR2026Project Grant

Principal investigators: Beug, Shawn T

Keywords: Adoptive Cell Therapy; Glioma; Iap Antagonists; Inhibitor Of Apoptosis; Pediatric Brain Tumor; Tumor Infiltrating Lymphocyte

$1,181,926

Small molecule enhancement of immune cell function to drive anti-cancer responses

Nominated PICIHR2026Project Grant

Principal investigators: Beug, Shawn T

Keywords: Breast Cancer; Cancer Cell Death; Smac Mimetics; Tumor Infiltrating Lymphoctes; Tumor Microenvironment

$1,178,100

Canada Research Chair - Tier 2

Nominated PICIHR2025Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Beug, Shawn T

Keywords: Crc

$500,000

Elucidating the immunomodulatory properties of small extracellular vesicles derived from SMAC mimetic treated cancer and immune cells

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Yin, Jordan J

Keywords: Animal Work; Cancer; Cell Culture; Exosomes; Flow Cytometry; Immune System; Immunotherapy; Nanoparticle Tracking Analysis; Small Extracellular Vesicles; Western Blot

$120,000

Development of Reovirus-based, orally administered, colon cancer vaccines.

Co-investigatorCIHR2024Project Grant

Principal investigators: Alain, Tommy

Keywords: Colon Cancer; Mouse Models; Oncolytic Viruses; Orally Administered; Polyps And Pre-Malignant Lesions; Prevention; Recombinant Viruses; Reovirus; Reverse Genetics; Tumour Antigens

$818,550

Development of an Oral Reovirus-Based Vaccination Platform for COVID-19.

Co-investigatorNSERC2020Alliance Grants

Principal investigators: Alain, Tommy

$50,000

Targeted immunotherapy for the treatment of brain cancer

Nominated PICIHR2019Project Grant

Principal investigators: Beug, Shawn T

Keywords: Biomarkers; Cancer; Glioblastoma; Immune Checkpoint Inhibitor; Immunotherapy; Inhibitors Of Apoptosis (Iap); Programmed Cell Death 1 (Pd-1); Smac Mimetic Compound (Smc)

$772,650

Targeted immunotherapy for the treatment of brain cancer

Nominated PICIHR2019PRIZE - Project Grant - PA: Prize: Early Career Investigator in Cancer

Principal investigators: Beug, Shawn T

Keywords: Biomarkers; Cancer; Glioblastoma; Immune Checkpoint Inhibitor; Immunotherapy; Inhibitors Of Apoptosis (Iap); Programmed Cell Death 1 (Pd-1); Smac Mimetic Compound (Smc)

$25,000

Canada Research Chairs - Tier 2

Nominated PICIHR2019Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Beug, Shawn T

Keywords: Crc

$600,000

Combination immunotherapy for pediatric brain cancer

Nominated PICIHR2018Operating Grant: SickKids-CIHR-IHDCYH New Investigator Grants

Principal investigators: Beug, Shawn T

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Catherine Tsilfidis

Ophthalmology

3 shared papers, latest 2006

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2026

Subject: Prospective PhD student: Crc Dear Professor Beug, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Sortilin regulates sorting and secretion of Sonic hedgehog." (2016), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Unlocking T cell therapy for pediatric brain tumors" (2026), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]