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Catherine Tsilfidis

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Associate ProfessorOphthalmologyUniversity of Ottawa

Catherine Tsilfidis

Associate Professor

Ophthalmology

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
6 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 8 research grants (4 NSERC, 4 CIHR), most recently in 2016.
Supervised 1 trainee who won CIHR awards, most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Research

Read how they describe their research on their University of Ottawa profile.

Apoptosis Leber'S Hereditary Optic Neuropathy Oxidative Stress Retinitis Pigmentosa

Latest papers

Beyond the snellen chart: exploring the clinical potential of sweep visual evoked potentials for visual acuity measurement.
Documenta ophthalmologica. Advances in ophthalmology · 2026
Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram.
Documenta ophthalmologica. Advances in ophthalmology · 2024
Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis.
Translational vision science & technology · 2023 · senior author

All 26 publications

Latest funding

Interrogating the Role of Chromatin Remodelling Proteins in Vision Health and Development using Mouse Models of Neurological System Diseases to Devise Novel Therapeutic Approaches for Visual Impairment
CIHR · 2023 · Supervisor
$180,000
STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition
CIHR · 2022 · Co-investigator
$2,911,416
STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition
CIHR · 2022 · Co-investigator
$727,855

All 11 grants and awards

26 publications.

Beyond the snellen chart: exploring the clinical potential of sweep visual evoked potentials for visual acuity measurement.

Hermas A, Dollin M, Karanjia R, Kantungane AL, Nguyen HA, Tsilfidis C, Coupland S

Documenta ophthalmologica. Advances in ophthalmology2026

DOI: 10.1007/s10633-026-10091-0 PMID: 41790402

Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram.

Hermas A, Tsilfidis C, Karanjia R, Miller G, Kantungane AL, El-Salibi A, Kherani IN, Bali S, Coupland S

Documenta ophthalmologica. Advances in ophthalmology2024

DOI: 10.1007/s10633-023-09960-9 PMID: 38243039

Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis.

Sobh M, Lagali PS, Ghiasi M, Montroy J, Dollin M, Hurley B, Leonard BC, Dimopoulos I, Lafreniere M, Fergusson DA, Lalu MM, Tsilfidis C

Translational vision science & technology2023Senior author

DOI: 10.1167/tvst.12.11.24 PMID: 37982768

Assessment of the uniform field electroretinogram for mouse retinal ganglion cell functional analysis.

Lagali PS, Shanmugalingam U, Baker AN, Mezey N, Smith PD, Coupland SG, Tsilfidis C

Documenta ophthalmologica. Advances in ophthalmology2023Senior author

DOI: 10.1007/s10633-023-09933-y PMID: 37106219

Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis.

Lithopoulos MA, Toussay X, Zhong S, Xu L, Mustafa SB, Ouellette J, Freitas-Andrade M, Comin CH, Bassam HA, Baker AN, Sun Y, Wakem M, Moreira AG, Blanco CL, Vadivel A, Tsilfidis C, Seidner SR, Slack RS, Lagace DC, Wang J, Lacoste B, Thébaud B

The Journal of clinical investigation2022

DOI: 10.1172/jci146095 PMID: 36136598

XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma.

Visuvanathan S, Baker AN, Lagali PS, Coupland SG, Miller G, Hauswirth WW, Tsilfidis C

Gene therapy2022Senior author

DOI: 10.1038/s41434-021-00281-7 PMID: 34363035

Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina.

Lagali PS, Zhao BYH, Yan K, Baker AN, Coupland SG, Tsilfidis C, Picketts DJ

Neuroscience2021

DOI: 10.1016/j.neuroscience.2020.10.030 PMID: 33197500

Immunopanning purification and culture of retinal ganglion cells from mouse.

Fang L, Huang T, Tsilfidis C

Journal of neuroscience methods2018Senior author

DOI: 10.1016/j.jneumeth.2018.02.010 PMID: 29474821

Overexpression of the X-Linked Inhibitor of Apoptosis Protects Against Retinal Degeneration in a Feline Model of Retinal Detachment.

Wassmer SJ, Leonard BC, Coupland SG, Baker AN, Hamilton J, Hauswirth WW, Tsilfidis C

Human gene therapy2017Senior author

DOI: 10.1089/hum.2016.161 PMID: 28335619

Retinal interneuron survival requires non-cell-autonomous Atrx activity.

Lagali PS, Medina CF, Zhao BY, Yan K, Baker AN, Coupland SG, Tsilfidis C, Wallace VA, Picketts DJ

Human molecular genetics2016

DOI: 10.1093/hmg/ddw306 PMID: 28173139

Interrogating the Role of Chromatin Remodelling Proteins in Vision Health and Development using Mouse Models of Neurological System Diseases to Devise Novel Therapeutic Approaches for Visual Impairment

SupervisorCIHR2023CIHR REDI Early Career Transition Award - Eye Diseases

Principal investigators: Lagali, Pamela S

Keywords: Chromatin Remodelling; Epigenetics; Gene; Gene Expression; Mouse Models; Neurodevelopment; Neuroprotection; Photoreceptors; Retinal Degeneration; Retinal Development

$180,000

STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition

Co-investigatorCIHR2022Training Grant: Clinical Trials Training Platforms

Principal investigators: Edwards, Jodi D; Menon, Bijoy K; Mercier, Catherine; Sakakibara, Brodie M; Singh, Nishita; Swartz, Richard

Keywords: Clinical Trials; Cognition; Diversity; Equity; Intersectionality; Mentorship; Stroke; Training

$2,911,416

STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition

Co-investigatorCIHR2022Training Grant: Clinical Trials Training Platforms - Indirect Costs

Principal investigators: Edwards, Jodi D; Menon, Bijoy K; Mercier, Catherine; Sakakibara, Brodie M; Singh, Nishita; Swartz, Richard

Keywords: Clinical Trials; Cognition; Diversity; Equity; Intersectionality; Mentorship; Stroke; Training

$727,855

Dedifferentiation induced by newt extract

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Tsilfidis, Catherine

$186,000

Combination therapy targeting apoptosis and oxidative stress for the treatment of retinal degenerations

Nominated PICIHR2015Operating Grant

Principal investigators: Tsilfidis, Catherine

Keywords: Apoptosis; Leber'S Hereditary Optic Neuropathy; Oxidative Stress; Retinitis Pigmentosa

$678,769

Anti-apoptotic therapy for the treatment of retinal degeneration: basic science to clinical application

Nominated PICIHR2009Team Grant: Vision, Hearing and Communication Disorders - LOI

Principal investigators: Tsilfidis, Catherine; Korneluk, Robert G

Keywords: Apoptosis; Gene Therapy; Nanoparticles; Retinal Degeneration

$3,739

CIHR Team in Apoptosis Prevention Therapy for the Treatment of Retinal Degeneration: Basic Science to Clinical Application

Nominated PICIHR2009Emerging Team Grant: From Genes to Proteins, Cells, Tissues and Patients

Principal investigators: Tsilfidis, Catherine; Korneluk, Robert G

Keywords: Apoptosis; Gene Therapy; Retinal Degeneration

$1,200,000

Apoptosis Prevention Therapy for the Treatment of Retinal Degeneration: Basic Science to Clinical Application

Nominated PICIHR2008Emerging Team Grant: From Genes to Proteins, Cells, Tissues and Patients - LOI

Principal investigators: Tsilfidis, Catherine; Korneluk, Robert G

Keywords: Apoptosis; Gene Therapy; Retinal Degeneration

Characterization of the dedifferentiation process induced by newt regeneration derived extracts

Principal investigatorNSERC2008Discovery Grants Program - Individual

Principal investigators: Tsilfidis, Catherine

$175,000

The identification of genes associated with the dedifferentiation process in newt forelimb regeneration

Principal investigatorNSERC2005Discovery Grants Program - Individual

Principal investigators: Tsilfidis, Catherine

$97,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Catherine Tsilfidis

Research

Latest papers

Latest funding

Beyond the snellen chart: exploring the clinical potential of sweep visual evoked potentials for visual acuity measurement.

Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram.

Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis.

Assessment of the uniform field electroretinogram for mouse retinal ganglion cell functional analysis.

Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis.

XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma.

Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina.

Immunopanning purification and culture of retinal ganglion cells from mouse.

Overexpression of the X-Linked Inhibitor of Apoptosis Protects Against Retinal Degeneration in a Feline Model of Retinal Detachment.

Retinal interneuron survival requires non-cell-autonomous Atrx activity.

Interrogating the Role of Chromatin Remodelling Proteins in Vision Health and Development using Mouse Models of Neurological System Diseases to Devise Novel Therapeutic Approaches for Visual Impairment

STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition

STROKECOG Platform: Innovative Clinical Trials Training Initiatives for STROKE and COGnition

Dedifferentiation induced by newt extract

Combination therapy targeting apoptosis and oxidative stress for the treatment of retinal degenerations

Anti-apoptotic therapy for the treatment of retinal degeneration: basic science to clinical application

CIHR Team in Apoptosis Prevention Therapy for the Treatment of Retinal Degeneration: Basic Science to Clinical Application

Apoptosis Prevention Therapy for the Treatment of Retinal Degeneration: Basic Science to Clinical Application

Characterization of the dedifferentiation process induced by newt regeneration derived extracts

The identification of genes associated with the dedifferentiation process in newt forelimb regeneration

Frequent collaborators

Shawn Beug

Rashmi Kothary

Baptiste Lacoste

Jing Wang

Carol Schuurmans