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Research
Latest papers
Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
The Journal of biological chemistry · 2012
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.
Journal of molecular biology · 2010
PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
Molecular cell · 2010
Latest funding
- $50,000
Canadian ANtibiotic prescribing feedback initiative: Building a national framework to combat AntiMicrobial Resistance in primary care (CANBuild-AMR) - Planning and Dissemination Grant
CIHR · 2025 · Co-investigator
- $15,000
Using audit and feedback to advance equity goals of learning health systems.
CIHR · 2025 · Co-investigator
- $2,000,000
SPOR Network in Diabetes and its Related Complications
CIHR · 2025 · Principal investigator
6 publications.
Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
Tchigvintsev A, Singer A, Brown G, Flick R, Evdokimova E, Tan K, Gonzalez CF, Savchenko A, Yakunin AF
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.
Tchigvintsev A, Xu X, Singer A, Chang C, Brown G, Proudfoot M, Cui H, Flick R, Anderson WF, Joachimiak A, Galperin MY, Savchenko A, Yakunin AF
PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
Navarre WW, Zou SB, Roy H, Xie JL, Savchenko A, Singer A, Edvokimova E, Prost LR, Kumar R, Ibba M, Fang FC
Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.
Kuznetsova E, Xu L, Singer A, Brown G, Dong A, Flick R, Cui H, Cuff M, Joachimiak A, Savchenko A, Yakunin AF
Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli.
Brown G, Singer A, Lunin VV, Proudfoot M, Skarina T, Flick R, Kochinyan S, Sanishvili R, Joachimiak A, Edwards AM, Savchenko A, Yakunin AF
Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
Savchenko A, Proudfoot M, Skarina T, Singer A, Litvinova O, Sanishvili R, Brown G, Chirgadze N, Yakunin AF
Canadian ANtibiotic prescribing feedback initiative: Building a national framework to combat AntiMicrobial Resistance in primary care (CANBuild-AMR) - Planning and Dissemination Grant
Principal investigators: Schwartz, Kevin L
Keywords: Antimicrobial Resistance; Antimicrobial Stewardship; Audit And Feedback; Knowledge Translation; Primary Care
Using audit and feedback to advance equity goals of learning health systems.
Principal investigators: Ivers, Noah M
Keywords: Audit And Feedback; Learning Health System; Quality Improvement
SPOR Network in Diabetes and its Related Complications
Principal investigators: Lewis, Gary F; Chouinor, Kathleen A; Farnsworth, Kate; Murphy, Christine A; Ramdass, Seeta; St Pierre, Martha M; Banerjee, Ananya T; Campbell, David J; Carpentier, André C; de Mestral, Charles; Dogba, Maman A; Forbes, Thomas; Ganann, Rebecca L; Kaplan, Alexander J; Kastner, Monika; King, Malcolm; Lipscombe, Lorraine; Maberley, David; McGavock, Jonathan M; Northwood, Melissa; Perkins, Bruce A; Rac, Valeria E; Rochon, Paula A; Selby, Peter L; Senior, Peter A; Sherifali, Diana T; Singer, Alexander G; Tchernof, André; Weisman, Alanna; Witteman, Holly M; Yeung Laiwah, Roseanne O
Keywords: Diabetes
An eHealth Technology Intervention Pragmatic trials Platform integrated in the Canadian Primary Care Sentinel Surveillance Network: The eTIPP-CPCSSN
Principal investigators: Gupta, Samir; Dickson, Grant P; Phillips, Lacey; Singer, Alexander G
Keywords: Chronic Obstructive Pulmonary Disease; Computerized Decision Support Systems; Ehealth; Information Systems Design; Knowledge Translation; Pragmatic Trials; Primary Care
Canadian ADAptive Platform Trial of COVID-19 Therapeutics in Community Settings (Can-ADAPT COVID)
Principal investigators: Pinto, Andrew D; Keynan, Yoav; Greiver, Michelle; Jüni, Peter; Lee, Todd C; McDonald, Emily G; Murthy, Srinivas; Selby, Peter L
Keywords: Adaptive Platform Trial; Covid-19; Nirmatrelvir; Out-Patient; Sars-Cov-2; Therapeutics
Canadian ADAptive Platform Trial of COVID-19 Therapeutics in Community Settings (Can-ADAPT COVID)
Principal investigators: Pinto, Andrew D; Keynan, Yoav; Greiver, Michelle; Jüni, Peter; Lee, Todd C; McDonald, Emily G; Murthy, Srinivas; Selby, Peter L
Keywords: Adaptive Platform Trial; Covid-19; Nirmatrelvir; Out-Patient; Sars-Cov-2; Therapeutics
National and Provincial Policies to support the Face of Primary Care
Principal investigators: Ivers, Noah M; Kaplan, David M
Keywords: Health Policy; Medical Office Assistant; Primary Care
Improving population health through addressing social determinants in urban primary healthcare
Principal investigators: Pinto, Andrew D; Weyman, Karen; Akbar, Nadine; Barber, David; Breton, Mylaine; Garies, Stephanie; Singer, Alexander G
Keywords: Implementation Science; Population Health; Primary Healthcare; Social Determinants Of Health
The KIdney aNd blooD prESsure ouTcomes - Determining best fOllow-up in hospitalized Children (KINDEST-DOC) study: A national study of the FILTR-CKD study group
Principal investigators: Zappitelli, Michael; Chanchlani, Rahul; Constantin, Evelyn; Dart, Allison B; Dionne, Janis M; Lefebvre, Claire; Morgan, Catherine J; Ulrich, Emma H; Widger, Kimberley A
Keywords: Acute Kidney Injury; Administrative Health Care Data; Chronic Kidney Disease; Focus Groups; Guidelines; Healthcare Delivery; Hypertension; Pediatric
Screening for Poverty And Related social determinants and intervening to improve Knowledge of and links to resources (SPARK) Study
Principal investigators: Pinto, Andrew D; Aubrey-Bassler, Kris; Burge, Frederick I; Jackson, Lois A; Katz, Alan; Muhajarine, Nazeem; Neudorf, Cordell (Cory) O; Robinson, Marjeiry
Keywords: Electronic Medical Record; Income; Poverty; Primary Care; Screening; Social Determinants Of Health; Social Needs; Sociodemographic Data
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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