Ashraf Kharrat, University of Toronto

Research

Infection Morbidity Mortality Neonate Outcomes Prevalence Shock Comparative Effectiveness Research

Latest papers

The association of in utero SARS-CoV-2 exposure on neurodevelopmental outcomes at 12 and 22 months.
Journal of perinatology : official journal of the California Perinatal Association · 2026 · first author
Protocol for developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia
BMJ Paediatrics Open · 2026
Impact of Systole Phase on Ventricular Outflow Tract Diameter and Cardiac Output Calculation in Infants Born Preterm: A Clinical Validation Study.
The Journal of pediatrics · 2025

All 25 publications

Latest funding

Developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia
CIHR · 2024 · Co-investigator
$612,000
Incidence and outcomes of neonatal septic shock in Canada: a nationwide population-based observational study
CIHR · 2023 · Nominated PI
$75,000
Infant and child health outcomes following SARS-CoV-2 infection in pregnancy
CIHR · 2023 · Co-investigator

All 7 grants and awards

25 publications.

01

The association of in utero SARS-CoV-2 exposure on neurodevelopmental outcomes at 12 and 22 months.

Kharrat A, Gleeson E, Pippert V, Doctor S, Campbell D, Taylor C, Vaz S, Dawood T, Lee S, Shah J, Kelly E, Shah PS

Journal of perinatology : official journal of the California Perinatal Association2026First author

DOI: 10.1038/s41372-026-02819-2 PMID: 42498798

02

Protocol for developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia

Li CZ, Tse-Chang A, Yoon EW, Paquette V, Roberts A, Afifi J, Yang CL, Khurshid F, Augustine S, Choudhury J

BMJ Paediatrics Open20262 citations

DOI: 10.1136/bmjpo-2025-004234

03

Impact of Systole Phase on Ventricular Outflow Tract Diameter and Cardiac Output Calculation in Infants Born Preterm: A Clinical Validation Study.

García-Gozalo M, Nagpal R, McNamara K, Kharrat A, Deshpande P, Lee S, Zhu F, Jain A

The Journal of pediatrics2025

DOI: 10.1016/j.jpeds.2025.114663 PMID: 40409358

04

Association of lung ultrasound score with large patent ductus arteriosus in preterm neonates during the transitional period.

Mohamed A, Mohsen N, Ibrahim J, Lee S, Kharrat A, Shah PS, Jain A

European journal of pediatrics2025

DOI: 10.1007/s00431-025-06186-6 PMID: 40392344

05

Impact of targeted neonatal echocardiography consultations for critically sick preterm neonates.

Joye S, Kharrat A, Zhu F, Deshpande P, Baczynski M, Jasani B, Lee S, Mertens LL, McNamara PJ, Shah PS, Weisz DE, Jain A

Archives of disease in childhood. Fetal and neonatal edition2025

DOI: 10.1136/archdischild-2024-327347 PMID: 39227145

06

Cardiopulmonary Physiology of Hypoxemic Respiratory Failure Among Preterm Infants with Septic Shock.

Kharrat A, Nissimov S, Zhu F, Deshpande P, Jain A

The Journal of pediatrics2025First author

DOI: 10.1016/j.jpeds.2024.114384 PMID: 39510164

07

Antibiotic stewardship in the neonatal intensive care unit and prevention of antimicrobial resistance.

Kharrat A, Tabbara N, Shah PS

Seminars in fetal & neonatal medicine2025First author

DOI: 10.1016/j.siny.2025.101666 PMID: 41038787

08

Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension

Baczynski M, Weisz D, Thomas L, Fevrier S, Castaldo M, Soraisham A, Hyderi A, Agarushi R, Bhattacharya S, Lalitha R

JAMA Network Open202511 citations

DOI: 10.1001/jamanetworkopen.2024.58843

09

Corticosteroid use in neonatal hypotension: A survey of Canadian neonatologists.

Kharrat A, Diambomba Y, Jain A

Pediatrics and neonatology2024First author

DOI: 10.1016/j.pedneo.2023.09.013 PMID: 38388227

10

Challenges in clinical identification of right ventricular dysfunction in preterm infants with persistent pulmonary hypertension of the newborn.

Zhu F, de Oliveira CB, Mohsen N, Kharrat A, Deshpande P, Mertens L, Jain A

Early human development2024

DOI: 10.1016/j.earlhumdev.2024.105942 PMID: 38306954

Developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia

Co-investigatorCIHR2024Project Grant

Principal investigators: Ting, Yuk Joseph; Beltempo, Marc; Shah, Prakeshkumar

Keywords: Neonate; Preterm; Ventilator-Associated Pneumonia

$612,000

Incidence and outcomes of neonatal septic shock in Canada: a nationwide population-based observational study

Nominated PICIHR2023Operating Grant: Data Analysis Using Existing CDN Databases and Cohorts

Principal investigators: Kharrat, Ashraf; Shah, Prakeshkumar

Keywords: Infection; Morbidity; Mortality; Neonate; Outcomes; Prevalence; Shock

$75,000

Infant and child health outcomes following SARS-CoV-2 infection in pregnancy

Co-investigatorCIHR2023Project Gr. PA: Res. on Prevention/Response to Covid-19/Similar Future Pandemics

Principal investigators: El-Chaar, Darine; Brophy, Jason C; Hawken, Steven

Keywords: Child Health; Covid-19; Health Determinants; Healthcare Utilization; Infant Health; Infection; Neurodevelopment; Pregnancy; Prenatal Exposures; Sars-Cov-2

Prediction of Intraventricular Hemmorhage using Echocardiography and Near Infrared Spectroscopy (PIE-NIRS)

Co-investigatorCIHR2022Operating Grant: SickKids-CIHR-IHDCYH New Investigator Grants

Principal investigators: Deshpande, Poorva

Keywords: .

$297,594

Infant and child health outcomes following SARS-CoV-2 infection in pregnancy

Co-investigatorCIHR2022Pr. Gr. - PA: Human Development Child and Youth Health - Mid Career Support

Principal investigators: El-Chaar, Darine; Brophy, Jason C; Hawken, Steven

Keywords: Covid-19; Health Determinants; Healthcare Utilization; Infant And Child; Neurodevelopment; Neurosensory Impairment; Pregnancy; Prenatal Exposures; Sars-Cov-2

$100,000

Dopamine vs. Norepinephrine for hypotension in very preterm infants with late-onset sepsis: A National Comparative Effectiveness Research (CER) Project

Principal investigatorCIHR2021Project Grant

Principal investigators: Jain, Amish; Kharrat, Ashraf; Shah, Prakeshkumar

Keywords: Comparative Effectiveness Research; Inotrope; Late-Onset Sepsis; Preterm

$473,761

REdefining the SignificancE and Treatment threshold for Patent Ductus Arteriosus in preterm infants (RESET-PDA)

Co-investigatorCIHR2020Project Grant

Principal investigators: Weisz, Dany E; Jain, Amish; Mertens, Luc; Shah, Prakeshkumar

Keywords: Comparative Effectiveness; Extremely Preterm; Mortality; Patent Ductus Arteriosus; Prediction Model; Prematurity; Preterm

$566,100

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Pediatrics
Pediatrics and Child Health
Medicine
Obstetrics & Gynecology
Li Ka Shing Knowledge
Obstétrique et gynécologie
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Deepak Louis

Pediatrics and Child Health

3 shared papers, latest 2026

Rohan D'Souza

Obstetrics & Gynecology

3 shared papers, latest 2022

Marc Beltempo

Obstétrique et gynécologie

1 shared papers, latest 2026

Douglas Campbell

Li Ka Shing Knowledge

1 shared papers, latest 2026

Shikha Gupta

Pediatrics

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Infection Dear Professor Kharrat, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The association of in utero SARS-CoV-2 exposure on neurodevelopmental outcomes at 12 and 22 months." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Incidence and outcomes of neonatal septic shock in Canada: a nationwide population-based observational study" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Ashraf Kharrat

Research

Latest papers

Latest funding

The association of in utero SARS-CoV-2 exposure on neurodevelopmental outcomes at 12 and 22 months.

Protocol for developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia

Impact of Systole Phase on Ventricular Outflow Tract Diameter and Cardiac Output Calculation in Infants Born Preterm: A Clinical Validation Study.

Association of lung ultrasound score with large patent ductus arteriosus in preterm neonates during the transitional period.

Impact of targeted neonatal echocardiography consultations for critically sick preterm neonates.

Cardiopulmonary Physiology of Hypoxemic Respiratory Failure Among Preterm Infants with Septic Shock.

Antibiotic stewardship in the neonatal intensive care unit and prevention of antimicrobial resistance.

Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension

Corticosteroid use in neonatal hypotension: A survey of Canadian neonatologists.

Challenges in clinical identification of right ventricular dysfunction in preterm infants with persistent pulmonary hypertension of the newborn.

Developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia

Incidence and outcomes of neonatal septic shock in Canada: a nationwide population-based observational study

Infant and child health outcomes following SARS-CoV-2 infection in pregnancy

Prediction of Intraventricular Hemmorhage using Echocardiography and Near Infrared Spectroscopy (PIE-NIRS)

Infant and child health outcomes following SARS-CoV-2 infection in pregnancy

Dopamine vs. Norepinephrine for hypotension in very preterm infants with late-onset sepsis: A National Comparative Effectiveness Research (CER) Project

REdefining the SignificancE and Treatment threshold for Patent Ductus Arteriosus in preterm infants (RESET-PDA)

Frequent collaborators

Amish Jain

Faith Zhu

Poorva Deshpande

Dany Weisz

Deepak Louis

Rohan D'Souza

Rohan D'Souza

Souvik Mitra

Luc Mertens

Gabriel Altit

Brigitte Lemyre

Marc Beltempo

Eugene Yoon

Gabriel Altit

Kyong-Soon Lee

Douglas Campbell

Amit Mukerji

Muzafar Gani Abdul Wahab

Marc Beltempo

Matthew Hicks

Amneet Sidhu

Shikha Gupta