Brent Williams, University of Toronto

Research

Acute Myeloid Leukemia Immunotherapy Leukemic Stem Cell Natural Killer Cell

Latest papers

A radiolabeled antibody targeting CD123(+) leukemia stem cells - initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML.
Leukemia research reports · 2015
MicroSPECT/CT imaging of primary human AML engrafted into the bone marrow and spleen of NOD/SCID mice using 111In-DTPA-NLS-CSL360 radioimmunoconjugates recognizing the CD123+ / CD131- epitope expressed by leukemia stem cells.
Leukemia research · 2014
Novel RAG1 mutation in a case of severe combined immunodeficiency.
Pediatrics · 2005

All 3 publications

Latest funding

Immunotherapy of leukemic stem cells
CIHR · 2013 · Nominated PI
$172,500
Immunotherapy of leukemic stem cells
CIHR · 2010 · Nominated PI
$172,500

All 2 grants and awards

3 publications.

01

A radiolabeled antibody targeting CD123(+) leukemia stem cells - initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML.

Leyton JV, Gao C, Williams B, Keating A, Minden M, Reilly RM

Leukemia research reports2015

DOI: 10.1016/j.lrr.2015.07.003 PMID: 26500848

02

MicroSPECT/CT imaging of primary human AML engrafted into the bone marrow and spleen of NOD/SCID mice using 111In-DTPA-NLS-CSL360 radioimmunoconjugates recognizing the CD123+ / CD131- epitope expressed by leukemia stem cells.

Leyton JV, Williams B, Gao C, Keating A, Minden M, Reilly RM

Leukemia research2014

DOI: 10.1016/j.leukres.2014.09.005 PMID: 25278187

03

Novel RAG1 mutation in a case of severe combined immunodeficiency.

Zhang J, Quintal L, Atkinson A, Williams B, Grunebaum E, Roifman CM

Pediatrics2005

DOI: 10.1542/peds.2005-0369 PMID: 16061569

Immunotherapy of leukemic stem cells

Nominated PICIHR2013CIHR Clinician Scientist - Phase 1

Principal investigators: Williams, Brent A

Keywords: Acute Myeloid Leukemia; Immunotherapy; Leukemic Stem Cell; Natural Killer Cell

$172,500

Immunotherapy of leukemic stem cells

Nominated PICIHR2010CIHR Clinician Scientist - Phase 1

Principal investigators: Williams, Brent A

Keywords: Acute Myeloid Leukemia; Immunotherapy; Leukemic Stem Cell; Natural Killer Cell

$172,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Mechanical Engineering
Department of Medical Biophysics
Department of Paediatrics
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Armand Keating

Mechanical Engineering

2 shared papers, latest 2015

Mark Minden

Department of Medical Biophysics

2 shared papers, latest 2015

Adelle Atkinson

Department of Paediatrics

1 shared papers, latest 2005

Write to this professor

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Applying for

Paper to mention

Subject: Prospective PhD student: Acute Myeloid Leukemia Dear Professor Williams, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "A radiolabeled antibody targeting CD123(+) leukemia stem cells - initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML." (2015), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]