Faculty profile

Charles De Mestral

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Associate ProfessorDepartment of SurgeryUniversity of Toronto

Charles De Mestral

Associate Professor

Department of Surgery

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
69 publications in the last five years, latest in 2026.
Senior (last) author on 13 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2025.
Supervised 1 trainee who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

129

Publications

788

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Education

MD
PhD
Medicine Preparatory Program

Profiles and links

University Profile Search on Google Scholar iDORCID

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Diabetes Foot Care Leg Amputation Peripheral Artery Disease Homelessness Population Health

Latest papers

Development, validation, and pilot implementation of a prognostic model to predict future foot complications among people with diabetes recently discharged from hospital.
Journal of clinical epidemiology · 2026 · senior author
Regional and Rural-Urban Differences in Incidence Rates of Types 1 and 2 Diabetes Mellitus-Related Foot Complications and Lower-Extremity Amputation in Selected Canadian Provinces and Territories.
Canadian journal of diabetes · 2026 · senior author
Canadian Patient Perspectives on Facilitators and Barriers to Diabetic Foot Ulcer Care: A Scoping Review.
Canadian journal of diabetes · 2026 · senior author

All 129 publications

Latest funding

Characterizing the Interplay Between Mental Health Conditions and Limb-Threatening Complications of Diabetes
CIHR · 2025 · Supervisor
$120,000
SPOR Network in Diabetes and its Related Complications
CIHR · 2025 · Principal investigator
$2,000,000
Understanding the Heightened Amputation Risk Among People Experiencing Homelessness: A Population-based Cohort Study
CIHR · 2023 · Nominated PI
$145,351

All 8 grants and awards

129 publications.

Development, validation, and pilot implementation of a prognostic model to predict future foot complications among people with diabetes recently discharged from hospital.

Roberts SB, Löffler A, Ramachandram D, Garay-Fernandez J, Norman M, Pow C, Razak F, Verma AA, de Mestral C

Journal of clinical epidemiology2026Senior author

DOI: 10.1016/j.jclinepi.2026.112295 PMID: 42061768

Regional and Rural-Urban Differences in Incidence Rates of Types 1 and 2 Diabetes Mellitus-Related Foot Complications and Lower-Extremity Amputation in Selected Canadian Provinces and Territories.

Kim AY, Hanley J, Fuhrer R, de Mestral C

Canadian journal of diabetes2026Senior author

DOI: 10.1016/j.jcjd.2026.05.006 PMID: 42218961

Canadian Patient Perspectives on Facilitators and Barriers to Diabetic Foot Ulcer Care: A Scoping Review.

Fikree S, Pandya R, Blanchette V, Weisz T, Iansavitchene A, de Mestral C

Canadian journal of diabetes2026Senior author

DOI: 10.1016/j.jcjd.2026.04.009 PMID: 42081974

Long-term Outcomes following Nonoperative Management of Acute Appendicitis: A Population-based Analysis.

Telesnicki T, Nantais J, De Mestral C, de Buck van Overstraeten A, Gomez D

Annals of surgery2026

DOI: 10.1097/sla.0000000000006555 PMID: 39411865

Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for peripheral arterial disease of the lower limbs.

Ma GW, Bernatchez J, Yarranton B, Dueck AD, Rajan DK, Forbes TL, de Mestral C, Kayssi A

The Cochrane database of systematic reviews2026

DOI: 10.1002/14651858.cd011319.pub3 PMID: 42573020

Diabetic foot screening programs through an implementation science lens: A rapid review.

Fakhfakh M, Andoulsi Y, Brousseau-Foley M, Pallin JA, Buckley CM, Drudi LM, de Mestral C, Kuhnke JL, McIntosh C, Blanchette V

International journal of nursing studies2026

DOI: 10.1016/j.ijnurstu.2026.105582 PMID: 42208095

Contemporary emergency management and 1-year outcomes of colonic diverticulitis: a population-based cohort study.

Telesnicki T, Stukel TA, Wilton AS, de Buck van Overstraeten A, de Mestral C, Gomez D

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2026

DOI: 10.1016/j.gassur.2025.102311 PMID: 41448529

Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning.

Li B, Eisenberg N, Beaton D, Lee DS, Al-Omran L, Wijeysundera DN, Hussain MA, Rotstein OD, Greco E, de Mestral C, Mamdani M, Roche-Nagle G, Al-Omran M

NPJ digital medicine2025

DOI: 10.1038/s41746-025-02187-9 PMID: 41345783

Evaluating the association between a backlog of scheduled colectomies for diverticulitis and concurrent rates of emergency diverticulitis procedures: a natural experiment using population-based data.

Telesnicki T, Stukel TA, de Buck van Overstraeten A, Wilton A, de Mestral C, Gomez D

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2025

DOI: 10.1016/j.gassur.2025.102257 PMID: 41101380

Predictors of inferior vena cava filter retrieval in a population-based Canadian cohort.

Ip S, Salata K, Luo J, de Mestral C, Roche-Nagle G

Journal of vascular surgery. Venous and lymphatic disorders2025

DOI: 10.1016/j.jvsv.2025.102283 PMID: 40581334

Characterizing the Interplay Between Mental Health Conditions and Limb-Threatening Complications of Diabetes

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Abi-Jaoude, Joanne

Keywords: Administrative Health Data; Anxiety; Depression; Diabetes; Leg Amputation; Mental Health; Patient Reported Outcomes; Peripheral Artery Disease

$120,000

SPOR Network in Diabetes and its Related Complications

Principal investigatorCIHR2025SPOR Networks - Knowledge Mobilization and Implementation Science - Extension

Principal investigators: Lewis, Gary F; Chouinor, Kathleen A; Farnsworth, Kate; Murphy, Christine A; Ramdass, Seeta; St Pierre, Martha M; Banerjee, Ananya T; Campbell, David J; Carpentier, André C; de Mestral, Charles; Dogba, Maman A; Forbes, Thomas; Ganann, Rebecca L; Kaplan, Alexander J; Kastner, Monika; King, Malcolm; Lipscombe, Lorraine; Maberley, David; McGavock, Jonathan M; Northwood, Melissa; Perkins, Bruce A; Rac, Valeria E; Rochon, Paula A; Selby, Peter L; Senior, Peter A; Sherifali, Diana T; Singer, Alexander G; Tchernof, André; Weisman, Alanna; Witteman, Holly M; Yeung Laiwah, Roseanne O

Keywords: Diabetes

$2,000,000

Understanding the Heightened Amputation Risk Among People Experiencing Homelessness: A Population-based Cohort Study

Nominated PICIHR2023Project Grant

Principal investigators: de Mestral, Charles

Keywords: Diabetes; Foot Care; Homelessness; Leg Amputation; Peripheral Artery Disease

$145,351

The Anesthesia for Lower limb revascularization to Optimize Functional OuTcomes (ALOFT) Trial: a pilot multicenter randomized trial

Co-investigatorCIHR2022Project Grant

Principal investigators: McIsaac, Daniel I; Jerath, Angela; Kidd, Gurlavine D; Roberts, Derek J; Saha, Tarit; Taljaard, Monica; Wijeysundera, Duminda N

Keywords: Anesthesia; Barriers And Facilitators; Function; Patient Reported Outcomes; Peripheral Vascular Disease; Pilot Trial; Randomized Trial

$202,725

Mobilizing Knowledge and Implementing Equitable and Cost-Effective Health and Social Care Services for Persons Living with Diabetes in Canada

Principal investigatorCIHR2021SPOR Networks - Knowledge Mobilization and Implementation Science

Principal investigators: Lewis, Gary F; MacPhail, Carolyn L; Murphy, Christine A; pelletier, Marc C; Ramdass, Seeta; Roche, Brooks; Banerjee, Ananya T; Bélanger, Mathieu; Cafazzo, Joseph A; Campbell, David J; Carpentier, André C; Castle, David; de Mestral, Charles; Després, Jean-Pierre; Dogba, Maman A; Forbes, Thomas; Ganann, Rebecca L; Greiver, Michelle; Kastner, Monika; King, Malcolm; Lipscombe, Lorraine; Maberley, David; Markle-Reid, Maureen Frances; McGavock, Jonathan M; Perkins, Bruce A; Rac, Valeria E; Rochon, Paula A; Selby, Peter L; Senior, Peter A; Sherifali, Diana T; Tchernof, André; Weisman, Alanna; Witteman, Holly M; Yeung Laiwah, Roseanne O

Keywords: Diabetes; Population Health

$3,744,045

The Surgical EQUITY initiative: Establishing equitable access to surgery following the pandemic

Co-investigatorCIHR2021Op. Gr.:Emerg. COVID-19 Res. Gaps & Priorities- Health care systems and services

Principal investigators: Gomez Jaramillo, David; Chan, Timothy; Sankar, Ashwin

Keywords: Access To Care; Marginalization; Rurality; Surgery

$220,596

Comprehensive Diabetes Management and its Association with the Risk of Leg Amputation: A Population-based Cohort Study

Nominated PICIHR2021Project Grant

Principal investigators: de Mestral, Charles

Keywords: Diabetes; Foot Care; Leg Amputation; Peripheral Artery Disease

$130,050

Improving Canadian Outcomes Research On the Novel SARS-CoV-2 using Analytics: the CORONA Consortium

Co-investigatorCIHR2020Op Gr: COVID-19 Rapid Research FO - Clinical Mgmt/Health System Interventions

Principal investigators: Lee, Douglas S; Mcalister, Finlay A

Keywords: Cardiovascular Disease; Health Services Research; Machine Learning; Medication Adherence; Observational Research; Outcomes Research; Risk Factors; Risk Prediction; Sars-Cov-2

$409,179

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Charles De Mestral

Research

Latest papers

Latest funding

Development, validation, and pilot implementation of a prognostic model to predict future foot complications among people with diabetes recently discharged from hospital.

Regional and Rural-Urban Differences in Incidence Rates of Types 1 and 2 Diabetes Mellitus-Related Foot Complications and Lower-Extremity Amputation in Selected Canadian Provinces and Territories.

Canadian Patient Perspectives on Facilitators and Barriers to Diabetic Foot Ulcer Care: A Scoping Review.

Long-term Outcomes following Nonoperative Management of Acute Appendicitis: A Population-based Analysis.

Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for peripheral arterial disease of the lower limbs.

Diabetic foot screening programs through an implementation science lens: A rapid review.

Contemporary emergency management and 1-year outcomes of colonic diverticulitis: a population-based cohort study.

Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning.

Evaluating the association between a backlog of scheduled colectomies for diverticulitis and concurrent rates of emergency diverticulitis procedures: a natural experiment using population-based data.

Predictors of inferior vena cava filter retrieval in a population-based Canadian cohort.

Frequent collaborators

Mohammed Al-Omran

Muhammad Mamdani

Graham Roche Nagle

Ahmed Kayssi

Barbara Haas

Avery Nathens

Subodh Verma

Sunjay Sharma

Wael Hanna

Bobby Shayegan

Mohammad Qadura

Rebecca Fuhrer

Andreas Laupacis

Jonathan Irish

Magali Brousseau-Foley

Virginie Blanchette

Fahad Razak

Vahid Sarhangian

Olli Saarela

Naheed Jivraj

Ashwin Sankar

Crystal Mackay

John Harlock

James Rutka

Fahad Razak

Ari Doumouras

Luc Dubois

Amol Verma

Hassan Mir

Graham Woodward

Conrad Pow

Sean van Diepen

Anik Giguère

Zaina Albalawi

Rahim Moineddin

Amol Verma

Timothy Jackson

Antoine Eskander