Faculty profile

Irene Karam

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Assistant ProfessorDepartment of Radiation OncologyUniversity of Toronto

Irene Karam

Assistant Professor

Department of Radiation Oncology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
50 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

890

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Long-term patient-reported outcomes in a randomized controlled trial of Mepitel Film versus standard of care for the prevention of acute breast radiation dermatitis
Breast Cancer Research and Treatment · 2026
What Is the Impact of Treatment De-Escalation on Patient-Reported Outcomes in Patients With T1-T2 Oropharyngeal Cancers? A Secondary Analysis of the ORATOR Studies.
International journal of radiation oncology, biology, physics · 2026
Head and Neck Cancers Medical Costs in a Universal Health System: A Population-Based Case-Control Study.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2026

All 78 publications

Latest funding

A Phase II Single Arm Trial of Elective Volume Adjusted De-Escalation Radiotherapy (EVADER) in Patients with Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma
CIHR · 2018 · Co-investigator
$860,628
A Phase II Single Arm Trial of Elective Volume Adjusted De-Escalation Radiotherapy (EVADER) in Patients with Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma
CIHR · 2017 · Co-investigator
$100,000

All 2 grants and awards

78 publications.

Long-term patient-reported outcomes in a randomized controlled trial of Mepitel Film versus standard of care for the prevention of acute breast radiation dermatitis

Bayrakdarian S, Hircock C, Wong HCY, Zhang L, Ding K, Karam I, Gallant F, Rakovitch E, Tran W, Soliman H

Breast Cancer Research and Treatment2026

DOI: 10.1007/s10549-026-07987-5

What Is the Impact of Treatment De-Escalation on Patient-Reported Outcomes in Patients With T1-T2 Oropharyngeal Cancers? A Secondary Analysis of the ORATOR Studies.

Dang A, Palma DA, Nichols AC, Warner A, Tran E, Bayley A, Sultanem K, Le H, Gaudet M, Karam I, Banerjee R, Tenenholz T, Winquist E, Theurer J, Goodman CD

International journal of radiation oncology, biology, physics2026

DOI: 10.1016/j.ijrobp.2026.06.3054 PMID: 42349663

Head and Neck Cancers Medical Costs in a Universal Health System: A Population-Based Case-Control Study.

Villemure-Poliquin N, Fu R, Chan KKW, Li Q, Ayoo K, Wright F, Karam I, Coburn NG, Hallet J, Eskander A

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2026Open Access

DOI: 10.1177/19160216251406521 PMID: 41689785

Implementation of Stereotactic Body Radiation Therapy SBRT for primary Primary Head and Neck Cancer.

Poon I, Karam I, Chin L, Galapin M

International journal of radiation oncology, biology, physics2026

DOI: 10.1016/j.ijrobp.2026.01.007 PMID: 42000366

Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC).

Aldohan M, Karam I, Safavi AH, Chin L, Zhang L, Gooanratne E, Galapin M, Eskander A, Higgins K, Enepekides D, Poon I

Head & neck2026

DOI: 10.1002/hed.70360 PMID: 42374609

Mepilex Lite dressing in the management of radiation dermatitis-a systematic review and meta-analysis of randomized controlled trials.

Wong HCY, Zhang B, Kagan S, Yang C, Tse SSW, Tang L, Hircock C, Lee SF, Hijal T, Safavi AH, Karam I, Chow E

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

DOI: 10.1007/s00520-026-10872-y PMID: 42257988

Retrospective Analysis of Acute Toxicity Following Breast Cancer Re-Irradiation.

Wang AJ, Kagan S, Zhang L, Hircock C, Bayrakdarian S, Chen H, Vesprini D, Soliman H, Chow E, Karam I

Clinical breast cancer2026Senior author

DOI: 10.1016/j.clbc.2026.07.024 PMID: 42574817

External Beam Breast and Chest Wall Re-Irradiation Following Resection of Ipsilateral Breast Cancer Recurrence: Dose-Toxicity Relationships and Long-Term Oncologic Outcomes.

Ghosh S, Soliman H, Chow E, Chen H, Leung E, Karam I, Rakovitch E, Safavi AH, Vesprini D, Czarnota GJ

Cancers2026

DOI: 10.3390/cancers18172878 PMID: 42738398

Radiation vs. trans-oral surgery for treatment de-escalation in HPV-related oropharyngeal cancers: Primary analysis of the ORATOR2 randomized trial.

Palma DA, Prisman E, Berthelet E, Tran E, Hamilton S, Wu J, Eskander A, Higgins K, Karam I, Poon I, Husain Z, Enepekides D, Hier M, Richardson K, Mlynarek A, Johnson-Obaseki S, Gaudet M, Bayley A, Dowthwaite S, Jackson JE, Dzienis M, O'Neil J, Chandarana S, Banerjee R, Hart R, Chung J, Tenenholtz T, Le H, Yoo J, Mendez A, Winquist E, Kuruvilla S, Stewart P, Warner A, Mitchell S, Chen J, Parker C, Kwan K, Theurer J, Bahig H, Christopoulos A, Mendez LC, Sathya J, Hammond JA, Read N, Venkatesan V, Fung K, Nichols AC

European journal of cancer (Oxford, England : 1990)202519 citations

DOI: 10.1016/j.ejca.2025.115343 PMID: 40121836

OPAR: A Randomized Trial of Partial Breast Irradiation in Five Fractions Once Daily for Early Breast Cancer

Kim D-H, Théberge V, Parpia S, Kong I, Provencher S, Yassa M, Perera F, Lavertu S, Rousseau P, Lee J

Journal of Clinical Oncology20257 citations

DOI: 10.1200/jco.24.00600

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Irene Karam

Research

Latest papers

Latest funding

Long-term patient-reported outcomes in a randomized controlled trial of Mepitel Film versus standard of care for the prevention of acute breast radiation dermatitis

What Is the Impact of Treatment De-Escalation on Patient-Reported Outcomes in Patients With T1-T2 Oropharyngeal Cancers? A Secondary Analysis of the ORATOR Studies.

Head and Neck Cancers Medical Costs in a Universal Health System: A Population-Based Case-Control Study.

Implementation of Stereotactic Body Radiation Therapy SBRT for primary Primary Head and Neck Cancer.

Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC).

Mepilex Lite dressing in the management of radiation dermatitis-a systematic review and meta-analysis of randomized controlled trials.

Retrospective Analysis of Acute Toxicity Following Breast Cancer Re-Irradiation.

External Beam Breast and Chest Wall Re-Irradiation Following Resection of Ipsilateral Breast Cancer Recurrence: Dose-Toxicity Relationships and Long-Term Oncologic Outcomes.

Radiation vs. trans-oral surgery for treatment de-escalation in HPV-related oropharyngeal cancers: Primary analysis of the ORATOR2 randomized trial.

OPAR: A Randomized Trial of Partial Breast Irradiation in Five Fractions Once Daily for Early Breast Cancer

A Phase II Single Arm Trial of Elective Volume Adjusted De-Escalation Radiotherapy (EVADER) in Patients with Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma

A Phase II Single Arm Trial of Elective Volume Adjusted De-Escalation Radiotherapy (EVADER) in Patients with Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma

Frequent collaborators

Edward Chow

Ian Poon

Danny Vesprini

Hany Soliman

William Tran

Antoine Eskander

Danny Enepekides

Hanbo Chen

Gregory Czarnota

Eileen Rakovitch

Rui Fu

Natalie Coburn

Kevin Higgins

Eric Leung

Ewa Szumacher

Justin Lee

Andrew Bayley

Julie Hallet

Lee Chin

Arjun Sahgal

Kelvin Chan

Marc Gaudet

Daniel Moore Freitas Palhares

Greg Stanisz

Anthony Nichols

Belinda Curpen

Eugene Yu

Pejman Maralani

Kucy Pon

Claire McCann

Pierre Rousseau

John Waldron

Merrylee McGuffin

Sten Myrehaug

Jolie Ringash

Brian O'Sullivan

Laura Snell

David Goldstein

Jennifer Kwan