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Research
Latest papers
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans.
Molecular neurodegeneration · 2021
Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans.
Development (Cambridge, England) · 2020
C. elegans PVF-1 inhibits permissive UNC-40 signalling through CED-10 GTPase to position the male ray 1 sensillum.
Development (Cambridge, England) · 2013 · senior author
Latest funding
- $156,000
Novel molecular mechanisms of cell migration in C. elegans
NSERC · 2017 · Principal investigator
- $33,000
Novel molecular mechanisms of cell migration in C. elegans
NSERC · 2016 · Principal investigator
- $613,435
Axon Guidance and Cell Migration Mechanisms in C. elegans
CIHR · 2015 · Nominated PI
6 publications.
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans.
Chen KS, Menezes K, Rodgers JB, O'Hara DM, Tran N, Fujisawa K, Ishikura S, Khodaei S, Chau H, Cranston A, Kapadia M, Pawar G, Ping S, Krizus A, Lacoste A, Spangler S, Visanji NP, Marras C, Majbour NK, El-Agnaf OMA, Lozano AM, Culotti J, Suo S, Ryu WS, Kalia SK, Kalia LV
Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans.
Modzelewska K, Brown L, Culotti J, Moghal N
C. elegans PVF-1 inhibits permissive UNC-40 signalling through CED-10 GTPase to position the male ray 1 sensillum.
Dalpe G, Tarsitano M, Persico MG, Zheng H, Culotti J
Semaphorin-1 and netrin signal in parallel and permissively to position the male ray 1 sensillum in Caenorhabditis elegans.
Dalpe G, Zheng H, Brown L, Culotti J
Semaphorin and Eph receptor signaling guide a series of cell movements for ventral enclosure in C. elegans.
Ikegami R, Simokat K, Zheng H, Brown L, Garriga G, Hardin J, Culotti J
The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans.
Steven R, Zhang L, Culotti J, Pawson T
Novel molecular mechanisms of cell migration in C. elegans
Principal investigators: Culotti, Joseph
Novel molecular mechanisms of cell migration in C. elegans
Principal investigators: Culotti, Joseph
Axon Guidance and Cell Migration Mechanisms in C. elegans
Principal investigators: Culotti, Joseph G
Keywords: Axon Guidance; C.Elegans; Cell Migration; Cell Polarity; Cross-Talk; Genetics; Molecular Biology; Netrin Signaling; Non-Axiomatic Guidance; Wnt Signaling
Molecular mechanisms of a voltage-gated potassium channel mediated suppression of an axon guidance defect in C. elegans
Principal investigators: Culotti, Joseph G
Keywords: Axon Guidance Defects; Eva-1 Receptor; Facilitation Of Unc-6/Netrin Attraction; Potassium Channel; Sax-3/Robo Receptor; Signal Transduction Mechanism; Slt-1/Slit Axon Guidance Cue; Suppression
Novel gene mutation that coordinately suppresses a cell migration dependent on multiple glycosylation pathways in C. elegans
Principal investigators: Culotti, Joseph
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
Principal investigators: Culotti, Joseph G
Keywords: Chairs
Axon guidance and cell migration mechanisms in C. elegans.
Principal investigators: Culotti, Joseph G
Keywords: Axon Guidance; Cell Migration; Novel Tgf-Beta Signaling; Pathway Funneling; Sensitization To Guidance Cues; Unc-6/Netrin Pathway
Identifying regulators of alpha-synuclein toxicity in dopaminergic neurodegeneration using a novel in vivo assay
Principal investigators: Kalia, Lorraine V
Keywords: Alpha-Synuclein; C. Elegans; Genetic Screen; Lewy Bodies; Molecular Signalling; Neurodegeneration; Parkinson'S Disease; Protein-Protein Interactions
Tubulin genes and microtubule mutants of C. elegans
Principal investigators: Culotti, Joseph
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine/Neurology
- Research Institute
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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