Laurent Bozec, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Dentistry and oral health Nanometrology Human biophysics Cultural property conservation Rare diseases Regenerative medicine (including stem cells and tissue engineering)Nanobiotechnology Educational administration, management and leadership

Latest papers

Biomimetic Collagen Scaffolds Natural Cross-Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair.
Journal of biomedical materials research. Part A · 2026 · senior author
Validation of clinically related aging models based on enamel wear.
Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026
Interfacial and mechanical effects of methylglyoxal on etched dentin: An in vitro study.
Journal of dentistry · 2026 · senior author

All 35 publications

Latest funding

INTEGRATION OF BIOMECHANICAL LOADING IN 3D TISSUE GRAFTS AND NOVEL MATERIALS DEVELOPMENT
NSERC · 2023 · Co-investigator
$149,990
Archival Parchments Rejuvenation: Re-engineering native collagen crosslinks for the test of time
NSERC · 2023 · Principal investigator
$213,774
Skin Investigation Network of Canada (SkIN Canada): Advancing interdisciplinary, patient-relevant research to improve skin health
CIHR · 2023 · Co-investigator
$2,000,000

All 4 grants and awards

35 publications.

01

Biomimetic Collagen Scaffolds Natural Cross-Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair.

Vaez M, Yen M, Ali A, Huang S, Zhong L, Schuh CM, Bozec L

Journal of biomedical materials research. Part A2026Senior author

DOI: 10.1002/jbm.a.70104 PMID: 42396752

02

Validation of clinically related aging models based on enamel wear.

Hajhamid B, Bozec L, Moghadam H, Tenenbaum H, De Souza GM, Somogyi-Ganss E

Journal of prosthodontics : official journal of the American College of Prosthodontists2026

DOI: 10.1111/jopr.13903 PMID: 39118276

03

Interfacial and mechanical effects of methylglyoxal on etched dentin: An in vitro study.

Alzubaidi W, Wang B, Vaez M, Neshatian M, Aguayo S, Thorpe S, Somogyi-Ganss E, Bozec L

Journal of dentistry2026Senior author

DOI: 10.1016/j.jdent.2026.106609 PMID: 41786238

04

Balancing Demineralisation and Collagen Integrity: A Nanoscale Analysis of Etching Time in Human Dentin.

Alzubaidi W, Ganss E, Vaez M, Neshatian M, Aguayo S, Somogyi-Ganss E, Bozec L

International dental journal2026Senior author

DOI: 10.1016/j.identj.2026.109413 PMID: 41653833

05

Label-free differentiation of classical and hypermobile Ehlers-Danlos syndromes using Mueller matrix polarimetry.

Tumanova K, Min E, Louie DC, Neshatian M, Shalviry S, Mittal N, Bozec L, Vitkin A

Biophotonics discovery2026

DOI: 10.1117/1.bios.3.1.015002 PMID: 42028051

06

Application of Raman Spectroscopy and Micro-Indentation to Micro-Map the Path and Boundary of NaOCI-Induced Dentine Collagen Changes in an Ex-Vivo Root Canal Irrigation Model.

Ng Y, Recchia M, Pereira C, Palmer G, Bozec L, Gulabivala K

Clinical and experimental dental research2025

DOI: 10.1002/cre2.70262 PMID: 41398997

07

DNA adenine methylation influences gene expression and biofilm formation in Streptococcus mutans.

Zhao H, Dufour D, Ghobaei N, Bozec L, Lévesque CM

Applied and environmental microbiology2025

DOI: 10.1128/aem.01094-25 PMID: 40985635

08

Glycated Cross-Linked Collagen Membranes with Tunable Permeability and Multifunctional Properties for Tissue Regeneration.

Vaez M, Odlyha M, Farzana S, Lee PC, Hinz B, Bozec L

ACS biomaterials science & engineering2025Senior author

DOI: 10.1021/acsbiomaterials.5c00120 PMID: 40214646

09

Effects of Ionizing Radiation on the Biophysical Properties of Type I Collagen Fibrils.

Ng K, Allam N, Neshatian M, Vaez M, Hirvonen LM, Lam E, Vitkin A, Bozec L

PloS one2025Senior author

DOI: 10.1371/journal.pone.0319777 PMID: 40173206

10

Collagen Hybridizing Peptides Promote Collagen Fibril Growth In Vitro.

Huang S, Ng N, Vaez M, Hinz B, Leong I, Bozec L

ACS applied bio materials2025Senior author

DOI: 10.1021/acsabm.4c01509 PMID: 40010706

INTEGRATION OF BIOMECHANICAL LOADING IN 3D TISSUE GRAFTS AND NOVEL MATERIALS DEVELOPMENT

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Kishen, Anil

$149,990

Archival Parchments Rejuvenation: Re-engineering native collagen crosslinks for the test of time

Principal investigatorNSERC2023Discovery Horizons

Principal investigators: Bozec, Laurent

Keywords: parchments; collagen; glycation; conservation; engineering; cultural heritage; ageing; materials sciences; collaboration; research translation

$213,774

Skin Investigation Network of Canada (SkIN Canada): Advancing interdisciplinary, patient-relevant research to improve skin health

Co-investigatorCIHR2023Network Gr. in Skin Health, Bone Health, and Muscular Dyst. - Skin Health

Principal investigators: Chan, An-Wen; Manion, Rachael; Drucker, Aaron M; Dutz, Jan P; Fradette, Julie; Germain, Lucie; Gniadecki, Robert; Grimshaw, Jeremy M; Litvinov, Ivan V; Logsetty, Sarvesh; Mydlarski, Paule R; Philip, Anie; Piguet, Vincent; Zhou, Youwen

Keywords: Clinical Trials; Observational Studies; Research Network; Skin Health; Skin Research; Translational Research

$2,000,000

Unlocking Collagen crosslinking

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Bozec, Laurent

$160,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Education Research
Department of Biomaterials and Biomedical Engineering
Matrix Dynamics Group
Mechanical and Industrial Engineering
Department of Oral Pathology and Cancer
Pediatrics and Physiology
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Eszter Somogyi-Ganss

Department of Education Research

4 shared papers, latest 2026

Boris Hinz

Matrix Dynamics Group

3 shared papers, latest 2025

Nimish Mittal

Faculty

3 shared papers, latest 2026

Ernest Lam

Department of Education Research

1 shared papers, latest 2025

Iona Leong

Department of Oral Pathology and Cancer

1 shared papers, latest 2025

Martin Post

Pediatrics and Physiology

1 shared papers, latest 2024

Andreas Mandelis

Mechanical and Industrial Engineering

1 shared papers, latest 2022

Janet Durbin

Faculty

1 shared papers, latest 2022

Anna Durbin

Faculty

1 shared papers, latest 2022

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2023

Subject: Prospective PhD student: Dentistry and oral health Dear Professor Bozec, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Biomimetic Collagen Scaffolds Natural Cross-Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Archival Parchments Rejuvenation: Re-engineering native collagen crosslinks for the test of time" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]