Faculty profile
Maria Rozakis-Adcock
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Latest papers
Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.
PloS one · 2013 · senior author
Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
American journal of physiology. Endocrinology and metabolism · 2010
Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids.
The Journal of endocrinology · 2008 · senior author
Latest funding
- $444,472
Role of PHIP in the Hormonal Control of Liver Gluconeogenic Networks
CIHR · 2013 · Nominated PI
- $17,500
Investigating the Role of PHIP1 in Human Breast Cancer
CIHR · 2009 · Supervisor
6 publications.
Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.
Lee A, Hakuno F, Northcott P, Pessin JE, Rozakis Adcock M
Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
Király MA, Campbell J, Park E, Bates HE, Yue JT, Rao V, Matthews SG, Bikopoulos G, Rozakis-Adcock M, Giacca A, Vranic M, Riddell MC
Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids.
Bikopoulos G, da Silva Pimenta A, Lee SC, Lakey JR, Der SD, Chan CB, Ceddia RB, Wheeler MB, Rozakis-Adcock M
Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.
Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A
Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
Oprescu AI, Bikopoulos G, Naassan A, Allister EM, Tang C, Park E, Uchino H, Lewis GF, Fantus IG, Rozakis-Adcock M, Wheeler MB, Giacca A
Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.
Podcheko A, Northcott P, Bikopoulos G, Lee A, Bommareddi SR, Kushner JA, Farhang-Fallah J, Rozakis-Adcock M
Role of PHIP in the Hormonal Control of Liver Gluconeogenic Networks
Principal investigators: Rozakis-Adcock, Maria
Keywords: Genetic Animal Models; Insulin/Glucagon; Liver; Pgc1/Torc2 Pathway; Transcriptional Regulation
Investigating the Role of PHIP1 in Human Breast Cancer
Principal investigators: Lee, Chan Mi
Keywords: Acinar Morphogenesis; Breast Cancer; Gene-Knockdown; Igf-Ir Cell Signalling; Mcf10a Cell Line; Mmtv Transgenic Mice; Transfection
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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