Faculty profile

Adria Giacca

ResearcherPhysiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Adria Giacca

Researcher

Physiology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
22 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (3 CIHR, 1 NSERC), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

110

Publications

240

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Diabetes Free Fatty Acids In Vivo Inflammation Lipotoxicity Obesity Damage Associated Molecular Patterns Fat

Latest papers

Protective effects of central leptin on whole-body energy homeostasis following acute olanzapine exposure.
Neuropharmacology · 2026
The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.
Advances in physiology education · 2026
Hepatic p38α at the forefront of diet-induced insulin resistance and hepatic steatosis.
American journal of physiology. Endocrinology and metabolism · 2026 · senior author

All 110 publications

Latest funding

Market Assessment of Insulin-Coated Stent Technology for Prevention of Restenosis
NSERC · 2023 · Principal investigator
$15,000
The role of NOD1 in obesity-associated diabetes
CIHR · 2019 · Nominated PI
$940,950
Unraveling the role of central insulin action in relation to glucose abnormalities in first-time antipsychotic users
CIHR · 2016 · Co-investigator
$420,750

All 8 grants and awards

110 publications.

Protective effects of central leptin on whole-body energy homeostasis following acute olanzapine exposure.

Singh R, Asgariroozbehani R, Wu S, Imami AS, Hamoud AR, Baranowski BJ, Jeromson S, Bernardo A, Prevot TD, Agarwal SM, Remington G, Wright DC, Giacca A, Mccullumsmith RE, Pereira S, Hahn MK

Neuropharmacology2026

DOI: 10.1016/j.neuropharm.2026.111180 PMID: 42705414

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.

Miliotis H, Buchan A, Wittnich C, Cox B, Brubaker PL, Giacca A, Belsham D

Advances in physiology education2026

DOI: 10.1152/advan.00060.2026 PMID: 42053450

Hepatic p38α at the forefront of diet-induced insulin resistance and hepatic steatosis.

Rivers SL, Tsakiridis N, Vlavcheski F, Pereira S, Rahman SMN, Li JX, Cash SB, Tan YF, Cummins CL, Tsiani E, Giacca A

American journal of physiology. Endocrinology and metabolism2026Senior author

DOI: 10.1152/ajpendo.00199.2024 PMID: 41213160

Nod1 Plays a Causal Role in Palmitate-Induced β-Cell Dysfunction In Vitro and In Vivo in Male Mice.

Yung JHM, Hoffman EG, Ivovic A, Rahman SMN, Desai T, Koulajian K, Mori Y, Maisonneuve C, Nissan M, Gelmez AB, Rabiee Y, Pereira S, Al-Rijjal D, Wheeler MB, Philpott DJ, Giacca A, Prentice KJ

Diabetes2026

DOI: 10.2337/db25-0752 PMID: 42770987

Longitudinal associations of serum fatty acids derived from dairy consumption with early prediabetes phenotypes: The PROspective Metabolism and ISlet cell Evaluation (PROMISE) cohort.

Yehia NA, Santaren I, Johnston LW, Sievenpiper JL, Giacca A, Retnakaran R, Harris SB, Bazinet RP, Hanley AJ

Clinical nutrition (Edinburgh, Scotland)2025

DOI: 10.1016/j.clnu.2025.10.012 PMID: 41202662

Protective effects of central leptin on whole-body energy homeostasis upon acute olanzapine exposure.

Asgariroozbehani R, Singh R, Wu S, Imami AS, Hamoud AR, Agarwal SM, Baranowski BJ, Jeromson S, Bernardo A, Prevot TD, Wright DC, Giacca A, Mccullumsmith RE, Pereira S, Hahn MK

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.04.11.648424 PMID: 41030962

Catechol-based chemistry for hypoglycemia-responsive delivery of zinc-glucagon via hydrogel-based microneedle patch technology.

GhavamiNejad A, Liu JF, Mirzaie S, Lu B, Samarikhalaj M, Giacca A, Wu XY

Nature communications2025

DOI: 10.1038/s41467-025-58278-4 PMID: 40169571

Metabolic phenotypes in a Lyz2Cre recombinase mouse model.

Rahman SMN, Yung JHM, Volchuk A, Goldenberg NM, Giacca A

Frontiers in immunology2025Senior author

DOI: 10.3389/fimmu.2025.1499858 PMID: 40170862

Antipsychotic-Induced Dysregulation of Glucose Metabolism Through the Central Nervous System: A Scoping Review of Animal Models.

Au E, Panganiban KJ, Wu S, Sun K, Humber B, Remington G, Agarwal SM, Giacca A, Pereira S, Hahn M

Biological psychiatry. Cognitive neuroscience and neuroimaging2025

DOI: 10.1016/j.bpsc.2024.10.001 PMID: 39461717

Protocol for the hyperinsulinemic euglycemic clamp to measure glucose kinetics in rats.

Pereira S, Hahn MK, Humber B, Chaudhry T, Wu S, Agarwal SM, Dimitrova N, Giacca A

STAR protocols2024Senior author

DOI: 10.1016/j.xpro.2024.103143 PMID: 38900633

Market Assessment of Insulin-Coated Stent Technology for Prevention of Restenosis

Principal investigatorNSERC2023Idea to Innovation

Principal investigators: Giacca, Adria MC

Keywords: cardiovascular; diabetes; insulin; market assessment; restonosis; stent

$15,000

The role of NOD1 in obesity-associated diabetes

Nominated PICIHR2019Project Grant

Principal investigators: Giacca, Adria

Keywords: Damage Associated Molecular Patterns; Fat; Innate Immunity; Pattern Recognition Receptors

$940,950

Unraveling the role of central insulin action in relation to glucose abnormalities in first-time antipsychotic users

Co-investigatorCIHR2016Project Grant

Principal investigators: Hahn, Margaret; Dash, Satya

Keywords: Antipsychotics; Cognition; Diabetes; Psychosis

$420,750

Hepatic signalling of glucose and lipid metabolism in vivo

Nominated PICIHR2016Project Grant

Principal investigators: Giacca, Adria

Keywords: Diabetes; Free Fatty Acids; Hyperinsulinemic Clamp; In Vivo; Inflammation; Insulin Resistance; Lipotoxicity; Liver; Obesity; Tracer Methodology

$761,175

Novel mediators of beta-cell lipotoxicity

Nominated PICIHR2012Operating Grant

Principal investigators: Giacca, Adria

Keywords: Beta Cell; Diabetes; Free Fatty Acids; Hyperglycemic Clamp; In Vivo; Inflammation; Lipotoxicity; Obesity; Oxidative Stress; Sirtuins

$774,325

Investigation of the biological effects of the polyphenol resveratrol on insulin producing and insulin target tissues

Co-investigatorNSERC2007Discovery Grants Program - Group

Principal investigators: Tsiani, Evangelia

$32,000

MEMS-based closed-loop drug delivery devices integrating stimulus-responsive nano hydrogels:

Co-investigatorNSERC2007Collaborative Health Research Projects

Principal investigators: Sun, Yu

$198,800

Investigation of the biological effects of the polyphenol resveratrol on skeletal muscle glucose transport system

Co-investigatorNSERC2004Discovery Grants Program - Group

Principal investigators: Tsiani, Evangelia

$103,170

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Adria Giacca

Research

Latest papers

Latest funding

Protective effects of central leptin on whole-body energy homeostasis following acute olanzapine exposure.

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.

Hepatic p38α at the forefront of diet-induced insulin resistance and hepatic steatosis.

Nod1 Plays a Causal Role in Palmitate-Induced β-Cell Dysfunction In Vitro and In Vivo in Male Mice.

Longitudinal associations of serum fatty acids derived from dairy consumption with early prediabetes phenotypes: The PROspective Metabolism and ISlet cell Evaluation (PROMISE) cohort.

Protective effects of central leptin on whole-body energy homeostasis upon acute olanzapine exposure.

Catechol-based chemistry for hypoglycemia-responsive delivery of zinc-glucagon via hydrogel-based microneedle patch technology.

Metabolic phenotypes in a Lyz2Cre recombinase mouse model.

Antipsychotic-Induced Dysregulation of Glucose Metabolism Through the Central Nervous System: A Scoping Review of Animal Models.

Protocol for the hyperinsulinemic euglycemic clamp to measure glucose kinetics in rats.

Market Assessment of Insulin-Coated Stent Technology for Prevention of Restenosis

The role of NOD1 in obesity-associated diabetes

Unraveling the role of central insulin action in relation to glucose abnormalities in first-time antipsychotic users

Hepatic signalling of glucose and lipid metabolism in vivo

Novel mediators of beta-cell lipotoxicity

Investigation of the biological effects of the polyphenol resveratrol on insulin producing and insulin target tissues

MEMS-based closed-loop drug delivery devices integrating stimulus-responsive nano hydrogels:

Investigation of the biological effects of the polyphenol resveratrol on skeletal muscle glucose transport system

Frequent collaborators

Gary Remington

Margaret Hahn

Ravi Retnakaran

Minna Woo

Amira Klip

Bernard Zinman

Yu Sun

Maria Rozakis-Adcock

Jan Ehses

Mahla Poudineh

Brian Cox

Denise Belsham

Khosrow Adeli

Satya Dash

Jonathan Schertzer

Gregory Steinberg

Mansoor Husain

Adria Giacca

Research

Latest papers

Latest funding

Protective effects of central leptin on whole-body energy homeostasis following acute olanzapine exposure.

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.

Hepatic p38&#x3b1; at the forefront of diet-induced insulin resistance and hepatic steatosis.

Nod1 Plays a Causal Role in Palmitate-Induced &#x3b2;-Cell Dysfunction In&#xa0;Vitro and In&#xa0;Vivo in Male Mice.

Longitudinal associations of serum fatty acids derived from dairy consumption with early prediabetes phenotypes: The PROspective Metabolism and ISlet cell Evaluation (PROMISE) cohort.

Protective effects of central leptin on whole-body energy homeostasis upon acute olanzapine exposure.

Catechol-based chemistry for hypoglycemia-responsive delivery of zinc-glucagon via hydrogel-based microneedle patch technology.

Metabolic phenotypes in a Lyz2Cre recombinase mouse model.

Antipsychotic-Induced Dysregulation of Glucose Metabolism Through the Central Nervous System: A Scoping Review of Animal Models.

Protocol for the hyperinsulinemic euglycemic clamp to measure glucose kinetics in rats.

Market Assessment of Insulin-Coated Stent Technology for Prevention of Restenosis

The role of NOD1 in obesity-associated diabetes

Unraveling the role of central insulin action in relation to glucose abnormalities in first-time antipsychotic users

Hepatic signalling of glucose and lipid metabolism in vivo

Novel mediators of beta-cell lipotoxicity

Investigation of the biological effects of the polyphenol resveratrol on insulin producing and insulin target tissues

MEMS-based closed-loop drug delivery devices integrating stimulus-responsive nano hydrogels:

Investigation of the biological effects of the polyphenol resveratrol on skeletal muscle glucose transport system

Frequent collaborators

Gary Remington

Margaret Hahn

Ravi Retnakaran

Minna Woo

Amira Klip

Bernard Zinman

Yu Sun

Maria Rozakis-Adcock

Jan Ehses

Mahla Poudineh

Brian Cox

Denise Belsham

Khosrow Adeli

Satya Dash

Jonathan Schertzer

Gregory Steinberg

Mansoor Husain

Hepatic p38α at the forefront of diet-induced insulin resistance and hepatic steatosis.

Nod1 Plays a Causal Role in Palmitate-Induced β-Cell Dysfunction In Vitro and In Vivo in Male Mice.