This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Dopamine mediates a directionally opposite correlation between empathy and the reinforcing effects of amphetamine and gambling in people with gambling disorder vs. healthy controls.
Pharmacology, biochemistry, and behavior · 2024 · first author
Association of cannabis use with neurocognition in adolescents with bipolar disorder.
Journal of psychopharmacology (Oxford, England) · 2023
Engineered highs: Reward variability and frequency as potential prerequisites of behavioural addiction.
Addictive behaviors · 2023 · senior author
Latest funding
- $569,926
Proof-of-Concept Double-Blind, Placebo-Controlled Trial of the Cognitive Enhancer, Memantine for Gambling Disorder
CIHR · 2024 · Principal investigator
- $1,750,000
Ontario-based Canadian Research Initiative in Substance Misuse Node Team (OCRINT)
CIHR · 2014 · Co-investigator
- $50,000
Canadian Research Initiative in Substance Misuse (CRISM) - Ontario-Based Team for Intervention Research in Substance Misuse
CIHR · 2013 · Co-investigator
34 publications.
Dopamine mediates a directionally opposite correlation between empathy and the reinforcing effects of amphetamine and gambling in people with gambling disorder vs. healthy controls.
Zack M, Behzadi A, Biback C, Chugani B, DiGiacomo D, Fang T, Houle S, Kalia A, Lobo D, Payer D, Poulos CX, Rusjan PM, Smart K, Tatone D, Warsh J, Wilson AA, Kennedy JL
Association of cannabis use with neurocognition in adolescents with bipolar disorder.
Sultan AA, Mio M, Dimick MK, Zou Y, Karthikeyan S, Kolla N, Lanctot K, Zack M, Goldstein BI
Engineered highs: Reward variability and frequency as potential prerequisites of behavioural addiction.
Clark L, Zack M
Priming effects of a slot machine game and amphetamine on probabilistic risk-taking in people with gambling disorder and healthy controls.
Zack M, Lobo D, Biback C, Fang T, Smart K, Tatone D, Kalia A, Digiacomo D, Kennedy JL
Dopaminergic signaling of uncertainty and the aetiology of gambling addiction.
Zack M, St George R, Clark L
Is (poly-) substance use associated with impaired inhibitory control? A mega-analysis controlling for confounders.
Liu Y, van den Wildenberg WPM, de Graaf Y, Ames SL, Baldacchino A, Bø R, Cadaveira F, Campanella S, Christiansen P, Claus ED, Colzato LS, Filbey FM, Foxe JJ, Garavan H, Hendershot CS, Hester R, Jester JM, Karoly HC, Kräplin A, Kreusch F, Landrø NI, Littel M, Loeber S, London ED, López-Caneda E, Lubman DI, Luijten M, Marczinski CA, Metrik J, Montgomery C, Papachristou H, Mi Park S, Paz AL, Petit G, Prisciandaro JJ, Quednow BB, Ray LA, Roberts CA, Roberts GMP, de Ruiter MB, Rupp CI, Steele VR, Sun D, Takagi M, Tapert SF, van Holst RJ, Verdejo-Garcia A, Vonmoos M, Wojnar M, Yao Y, Yücel M, Zack M, Zucker RA, Huizenga HM, Wiers RW
Impulsivity moderates the effects of dopamine D2 and mixed D1-D2 antagonists in individuals with gambling disorder.
Zack M, Lobo D, Biback C, Fang T, Smart K, Tatone D, Kalia A, Digiacomo D, Kennedy JL
Neuroimaging of reward mechanisms in Gambling disorder: an integrative review.
Clark L, Boileau I, Zack M
Prevalence of Fetal Alcohol Exposure by Analysis of Meconium Fatty Acid Ethyl Esters; A National Canadian Study.
Delano K, Koren G, Zack M, Kapur BM
How uncertainty begets hope: A model of adaptive and maladaptive seeking behavior.
Zack M
Proof-of-Concept Double-Blind, Placebo-Controlled Trial of the Cognitive Enhancer, Memantine for Gambling Disorder
Principal investigators: Le Foll, Bernard; Zack, Martin H
Keywords: Attrition; Cognitive Inflexibility; Gambling Disorder; Memantine; Pharmacotherapy; Proof-Of-Concept; Sensitization
Ontario-based Canadian Research Initiative in Substance Misuse Node Team (OCRINT)
Principal investigators: Fischer, Benedikt; Czukar, Gail F; Long, Dennis; Mckeown, David J; Kelly, Len; Rehm, Jürgen T; Werb, Daniel M
Keywords: Evidence-Based; Illicit Drugs; Interventions; Knowledge Translation; Multi-Site Studies; Policy; Prescription Drugs; Prevention; Substance Abuse; Treatment
Canadian Research Initiative in Substance Misuse (CRISM) - Ontario-Based Team for Intervention Research in Substance Misuse
Principal investigators: Rehm, Jürgen T; Kelly, David H; Long, Dennis; Fischer, Benedikt; Kelly, Len; Tyndall, Mark W
Keywords: Disease Burden; Evidence-Based; Illicit Drug Use; Interventions; Policy; Prescription Drug Misuse; Prevention; Research Network; Treatment
Comparative effects of a D2 and mixed D1-D2 dopamine antagonist on gambling and amphetamine reinforcement in pathological gamblers and healthy controls
Principal investigators: Zack, Martin H
Keywords: Amphetamine; D1 And D2 Receptors; Dopamine Antagonists; Pathological Gambling; Priming; Reinforcement
Probing the role of dopamine in co-morbid pathological gambling and Parkinson's disease: Behavioural pharmacology, electrophysiology, neuroimaging, and genetics.
Principal investigators: Zack, Martin H; Beninger, Richard J; Kennedy, James L; Kish, Stephen J; Segalowitz, Sidney J
Keywords: Amphetamine; Behavioural Pharmacology; Dopamine Agonist; Electrophysiology; Parkinson'S Disease; Pathological Gambling; Positron Emission Tomography; Pramipexole; Reward Seeking; Risk-Taking
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Family and Community Medicine
- Psychiatry
- Positron, Emission Tomography (PET Centre)
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Isabelle Boileau
Faculty
6 shared papers, latest 2019
Kelly Smart
Faculty
4 shared papers, latest 2024
Peter Selby
Department of Family and Community Medicine
3 shared papers, latest 2013
Antonio Strafella
Faculty
2 shared papers, latest 2016
Pablo Rusjan
Positron, Emission Tomography (PET Centre)
1 shared papers, latest 2015
Nathan Kolla
Psychiatry
1 shared papers, latest 2023
Bernard Le Foll
Department of Family and Community Medicine
1 shared papers, latest 2015
Krista Lanctôt
Psychiatry
1 shared papers, latest 2023
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