Mel Silverman, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia.
American journal of physiology. Cell physiology · 2009 · senior author
Reanalysis of structure/function correlations in the region of transmembrane segments 4 and 5 of the rabbit sodium/glucose cotransporter.
Biochemical and biophysical research communications · 2009 · senior author
Effects on conformational states of the rabbit sodium/glucose cotransporter through modulation of polarity and charge at glutamine 457.
Biophysical journal · 2009 · senior author

All 8 publications

8 publications.

01

Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia.

Goldenberg NM, Silverman M

American journal of physiology. Cell physiology2009Senior author

DOI: 10.1152/ajpcell.00286.2009 PMID: 19641095

02

Reanalysis of structure/function correlations in the region of transmembrane segments 4 and 5 of the rabbit sodium/glucose cotransporter.

Liu T, Speight P, Silverman M

Biochemical and biophysical research communications2009Senior author

DOI: 10.1016/j.bbrc.2008.11.015 PMID: 19013429

03

Effects on conformational states of the rabbit sodium/glucose cotransporter through modulation of polarity and charge at glutamine 457.

Liu T, Krofchick D, Silverman M

Biophysical journal2009Senior author

DOI: 10.1016/j.bpj.2008.09.045 PMID: 19167319

04

Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding.

Liu T, Lo B, Speight P, Silverman M

American journal of physiology. Cell physiology2008Senior author

DOI: 10.1152/ajpcell.90602.2007 PMID: 18448629

05

Golgi-bound Rab34 is a novel member of the secretory pathway.

Goldenberg NM, Grinstein S, Silverman M

Molecular biology of the cell200764 citationsSenior authorOpen Access

DOI: 10.1091/mbc.e06-11-0991 PMID: 17881736

06

A glutamine to glutamate mutation at position 170 (Q170E) in the rabbit Na+/glucose cotransporter, rSGLT1, enhances binding affinity for Na+.

Huntley SA, Krofchick D, Silverman M

Biochemistry2006Senior author

DOI: 10.1021/bi052267m PMID: 16584200

07

Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.

Speight P, Silverman M

Traffic (Copenhagen, Denmark)2005Senior author

DOI: 10.1111/j.1600-0854.2005.00321.x PMID: 16138900

08

Description of a PCR-based technique for DNA splicing and mutagenesis by producing 5' overhangs with run through stop DNA synthesis utilizing Ara-C.

Ailenberg M, Goldenberg NM, Silverman M

BMC biotechnology2005Senior author

DOI: 10.1186/1472-6750-5-23 PMID: 16137330

Frequent collaborators

Sergio Grinstein

Institute of Medical Science

1 shared papers, latest 2007

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Subject: Prospective PhD student Dear Professor Silverman, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia." (2009), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]