Faculty profile

Michael Fralick

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Michael Fralick

Researcher

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
76 publications in the last five years, latest in 2026.
Senior (last) author on 24 recent papers, a sign of leading a research group.
Principal investigator on 3 research grants (3 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

135

Publications

483

Citations

h-index

165

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Covid-19 Environmental Surveillance Influenza Long-Term Care Homes Pathogen Surveillance Respiratory Syncytial Virus (Rsv)Sars-Cov-2 Animal Shelters

Latest papers

Defining a Non-Inferiority Margin for Delirium Resolution in a Clinical Trial of Older Adults With Bacteriuria and Abnormal Urine Tests.
Journal of the American Geriatrics Society · 2026
Targeted metatranscriptomic detection of viruses from floors for simultaneous evaluation of respiratory disease burden and viral variant identification.
mSphere · 2026
Association of Sedating vs. Non-Sedating Antihistamines With Delirium Among Hospitalized Older Adults.
Journal of the American Geriatrics Society · 2026

All 135 publications

Latest funding

GLP-1 Receptor Agonists: Exploring Adverse Drug Events in Older Adults
CIHR · 2025 · Co-investigator
$100,000
BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections
CIHR · 2025 · Co-investigator
$1,908,674
Co-Designing a Culturally Adapted Self-Management Health Intervention for Indian, Pakistani and Sri Lankan Older Adults Living with Diabetes and Their Family Caregivers in Ontario
CIHR · 2025 · Co-investigator
$474,299

All 23 grants and awards

135 publications.

Defining a Non-Inferiority Margin for Delirium Resolution in a Clinical Trial of Older Adults With Bacteriuria and Abnormal Urine Tests.

Bogler O, Fralick M, Kandel C, Stall NM, Prabaharan G, Hodzic-Santor E, Marcantonio ER, Reppas-Rindlisbacher C

Journal of the American Geriatrics Society2026

DOI: 10.1111/jgs.70408 PMID: 41918398

Targeted metatranscriptomic detection of viruses from floors for simultaneous evaluation of respiratory disease burden and viral variant identification.

Carroll AC, Hinz A, Hicks AMA, Khov E, Van Bakel T, Doukhanine E, Fralick M, Nott C, Kassen R, Thampi N, Hug LA, MacFadden D, Wong A

mSphere2026

DOI: 10.1128/msphere.00086-26 PMID: 42007699

Association of Sedating vs. Non-Sedating Antihistamines With Delirium Among Hospitalized Older Adults.

Drucker AM, Bridgman AC, Imrit MA, Roberts SB, Tadrous M, Stall NM, Fralick M, Watt J, Verma AA, Razak F

Journal of the American Geriatrics Society2026

DOI: 10.1111/jgs.70323 PMID: 41604345

Systemic therapies for psoriatic disease and serious adverse events in older adults: A population-based cohort study.

Drucker AM, Sutradhar R, Ling V, Eder L, Gomes T, Fralick M, Iskandar RJ, Li P, MacDougall S, Manolson M, Rochon PA, Tadrous M

The Journal of investigative dermatology2026

DOI: 10.1016/j.jid.2025.10.604 PMID: 41248822

Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes.

Bakhsh A, Saleemi A, Budhram D, Zhang Y, Bapat P, Abuabat MI, Verhoeff NJ, Mumford D, Orszag A, Fralick M, Weisman A, Cheema W, Waniss MR, Ouimet JP, Tomlinson G, Cherney DZI, Lovblom LE, Perkins BA

Diabetes care2026

DOI: 10.2337/dc25-1955 PMID: 41591367

Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection: A Multicentre, Pragmatic, Randomized Trial-Vanguard Results.

Fralick M, Stall NM, Zorcic K, Reppas-Rindlisbacher C, Kaplovitch E, Li AS, MacFadden DR, Kobewka D, Castellani L, Parsons P, McGeer A, McCready J, Lim B, Hodzic-Santor E, Kandel C, A‐DONUT Study Team

Journal of the American Geriatrics Society2026First author

DOI: 10.1111/jgs.70480 PMID: 42175687

Detectable C-Peptide and Diabetic Ketoacidosis Risk in Type 1 Diabetes.

Abuabat MI, Budhram D, Bapat P, Bakhsh A, Zhang Y, Cheema W, Verhoeff NJ, Mumford D, Orszag A, Fralick M, Weisman A, Lovblom LE, Perkins BA

Diabetes care2026

DOI: 10.2337/dc26-0220 PMID: 42423477

Trial Files: Leveraging large language models to summarize practice-changing clinical trials for clinicians.

Zorcic K, Bartsch E, Lim B, McCallum G, Van Bakel T, Hacker A, Fralick M

PloS one2026Senior author

DOI: 10.1371/journal.pone.0351135 PMID: 42566403

The Minimum Frequency of Well-Day Capillary Blood Ketone Testing Needed to Predict 1-Month Diabetic Ketoacidosis Risk in Type 1 Diabetes.

Zhang Y, Budhram D, Bapat P, Dhaliwal S, Parikh E, Gad H, Orszag A, Cheema W, Bakhsh A, Verhoeff NJ, Weisman A, Fralick M, Ivers NM, Cherney DZI, Tomlinson G, Mumford D, Lovblom LE, Perkins BA

Diabetes care2026

DOI: 10.2337/dc26-1110 PMID: 42663523

Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia

Lee TC, Barina LA, Walls G, Goodman AL, Yahav D, Cheng MP, Bonten M, Bowen AC, Boyles T, Daneman N

New England Journal of Medicine202613 citations

DOI: 10.1056/nejmoa2506905

GLP-1 Receptor Agonists: Exploring Adverse Drug Events in Older Adults

Co-investigatorCIHR2025Project Grant - Priority Announcement: Patient-Oriented Research

Principal investigators: Rochon, Paula A; Stall, Nathan M

Keywords: Adverse Drug Events; Aging; Glp-1 Receptor Agonists; Older Women; Ozempic; Rybelsus

$100,000

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2025Project Grant

Principal investigators: Daneman, Nick; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Ong, Sean W; Pinto, Ruxandra; Rogers, Benjamin A

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Duration; Antibiotic Oral Switch; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Clinical Trial

$1,908,674

Co-Designing a Culturally Adapted Self-Management Health Intervention for Indian, Pakistani and Sri Lankan Older Adults Living with Diabetes and Their Family Caregivers in Ontario

Co-investigatorCIHR2025Project Grant

Principal investigators: Kokorelias, Kristina M; Al-Hamad, Areej S; Harris, Maurita T; Metersky, Kateryna; YASIN, YASIN

Keywords: Aging; Culturally Sensitive Care; Diabetes; Implementation Science; Qualitative; Stigma

$474,299

Avian influenza suRveillance in Companion animal and Human healthcare settings [ARCH]

Nominated PICIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Fralick, Michael P; Hug, Laura A; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Wong, Alex

Keywords: Animal Shelters; Avian Influenza A; Environmental Surface Surveillance; H5n1; Hospitals; One Health; Pandemic Surveillance; Veterinary Clinics; Whole Genome Sequencing; Wildlife Rehabilitation

$150,000

Volunteer facilitated Discharge Assistance and Supports at Home (DASH) for people with stroke: An effectiveness-implementation hybrid trial.

Co-investigatorCIHR2023Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant

Principal investigators: Nelson, Michelle L; Ludwig Prout, Brina; Sperling, Christina; Bayley, Mark T; Graham, Ian D; Hebert, Paul C; Kokorelias, Kristina M; Singh, Hardeep

Keywords: Community-Based Services; Cost Effectiveness; Effectiveness-Implementation Trial; Intersectoral Partnership; Patient Oriented Research; Stroke; Transitions Of Care; Volunteers

$790,807

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

Nominated PICIHR2023Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Fralick, Michael P; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Wong, Alex

Keywords: Covid-19; Environmental Surveillance; Influenza; Long-Term Care Homes; Pathogen Surveillance; Respiratory Syncytial Virus (Rsv); Sars-Cov-2

$100,000

Nirmatrelvir/ritonavir (Paxlovid) in the prevention of long-term cardiovascular outcomes: The paxloviD Effectiveness For the prEvention of loNg coviD (DEFEND) clinical trial.

Co-investigatorCIHR2023Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Quinn, Kieran L; Cheung, Angela M; Fowler, Robert A; Hebert, Paul C; Johnstone, Jennie; Lee, Douglas S; Razak, Fahad; Taljaard, Monica; Verma, Amol

Keywords: Chronic Cardiovascular Disease; Long Covid; Nirmatrelvir/Ritonavir; Paxlovid; Post Acute Sequelae Of Covid-19; Post Covid-19 Condition; Prevention; Sars-Cov-2 Infection

$100,000

Canadian Critical Care Trials Group COVID-19 Response: defining critical care capacity in Canada; testing treatments through large-scale adaptive clinical trials; & establishing the evidence base to inform clinical and health system management decisions

Co-investigatorCIHR2022Operating Grant: CNCCTN Extension - Indirect Costs

Principal investigators: Fowler, Robert A; Adhikari, Neill K; Archambault, Patrick; Bagshaw, Sean M; Binnie, Alexandra; Chasse, Michael; Cook, Deborah J; Daneman, Nick; Fiest, Kirsten M; Fox-Robichaud, Alison E; Goligher, Ewan C; Herridge, Margaret S; Kho, Michelle E; Lamontagne, Francois; Lawler, Patrick R; Lee, Todd C; Marshall, John C; McDonald, Emily G; McNally, James D; Meade, Maureen O; Mehta, Sangeeta; Menon, Kusum; Murthy, Srinivas; O'Hearn, Katharine J; Piquette, Dominique; Rochwerg, Bram N; Russell, James A; Tsang, Jennifer L; Turgeon, Alexis F; Wollny, Krista; Yada, Nicole; Zarychanski, Ryan

Keywords: Clinical Trials; Covid-19; Network

$1,000,000

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

Nominated PICIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Fralick, Michael P; Castellani, Lucas; Hug, Laura A; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Thampi, Nisha; Wong, Alex

Keywords: Clostridioides Difficile (C. Difficile); Covid-19; Environmental Surveillance; Influenza; Long-Term Care Homes; Nosocomial Infections; Pathogen Surveillance; Respiratory Syncytial Virus (Rsv); Sars-Cov-2; Vancomycin-Resistant Enterococcus (Vre)

$100,000

Investigating variation in the inpatient allocation of scarce COVID-19 therapeutics: Equity and Clinical Outcomes

Co-investigatorCIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Razak, Fahad; Baker, Andrew J; Chan, Timothy; Gibson, Jennifer; Leung, Elizabeth; Mamdani, Muhammad; Morris, Andrew M; Pai, Menaka; Rosella, Laura C; Sarhangian, Vahid; Siddiqi, Arjumand; Verma, Amol

Keywords: Covid-19; Drug Shortages; Ethical Framework; Health Equity; Health Systems; Medications; Patient Outcomes; Processes Of Inpatient Care; Resource Allocation

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Michael Fralick

Research

Latest papers

Latest funding

Defining a Non-Inferiority Margin for Delirium Resolution in a Clinical Trial of Older Adults With Bacteriuria and Abnormal Urine Tests.

Targeted metatranscriptomic detection of viruses from floors for simultaneous evaluation of respiratory disease burden and viral variant identification.

Association of Sedating vs. Non-Sedating Antihistamines With Delirium Among Hospitalized Older Adults.

Systemic therapies for psoriatic disease and serious adverse events in older adults: A population-based cohort study.

Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes.

Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection: A Multicentre, Pragmatic, Randomized Trial-Vanguard Results.

Detectable C-Peptide and Diabetic Ketoacidosis Risk in Type 1 Diabetes.

Trial Files: Leveraging large language models to summarize practice-changing clinical trials for clinicians.

The Minimum Frequency of Well-Day Capillary Blood Ketone Testing Needed to Predict 1-Month Diabetic Ketoacidosis Risk in Type 1 Diabetes.

Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia

Frequent collaborators

Fahad Razak

Fahad Razak

Michael Colacci

Caroline Nott

Caroline Nott

Rees Kassen

Alex Wong

Alanna Weisman

Alex Wong

Rees Kassen

Terence Tang

Lauren Lapointe-Shaw

Amol Verma

Amol Verma

Muhammad Mamdani

Tara Gomes

Nisha Thampi

George Tomlinson

Mina Tadrous

Nick Daneman

Ruxandra Pinto

Laveena Munshi

Jennifer Tsang

Peter Daley

Antonios Douros

Travis Carpenter

Paula James

Derek MacFadden

Jennifer Grant

Daniel Beriault

Ayodele Odutayo

Ameeta Singh

Eitan Amir

Michael Fralick

Nick Daneman

Jennifer Grant

Ranjani Somayaji

Jennifer Tsang

Karen Wong

Ameeta Singh