William Hutchison, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Clinico-physiological correlates of Parkinson's disease from multi-resolution basal ganglia recordings.
NPJ Parkinson's disease · 2024
Acute low frequency dorsal subthalamic nucleus stimulation improves verbal fluency in Parkinson's disease.
Brain stimulation · 2021
Subthalamic suppression defines therapeutic threshold of deep brain stimulation in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry · 2019 · senior author

All 8 publications

Latest funding

Developing a Biologically-realistic Model-based Approach for Generating Deep Brain Stimulation Patterns
CIHR · 2023 · Co-investigator
$841,500
Saccade-related beta band activity in local field potentials recorded from human basal ganglia
CIHR · 2010 · Supervisor
$45,000
Dopamine and synaptic plasticity in human substantia nigra pars reticulata
CIHR · 2009 · Nominated PI
$490,745

All 3 grants and awards

8 publications.

01

Clinico-physiological correlates of Parkinson's disease from multi-resolution basal ganglia recordings.

Sumarac S, Youn J, Fearon C, Zivkovic L, Keerthi P, Flouty O, Popovic M, Hodaie M, Kalia S, Lozano A, Hutchison W, Fasano A, Milosevic L

NPJ Parkinson's disease202416 citationsOpen Access

DOI: 10.1038/s41531-024-00773-4 PMID: 39261476

02

Acute low frequency dorsal subthalamic nucleus stimulation improves verbal fluency in Parkinson's disease.

Lee DJ, Drummond NM, Saha U, De Vloo P, Dallapiazza RF, Gramer R, Al-Ozzi TM, Lam J, Loh A, Elias GJB, Boutet A, Germann J, Hodaie M, Fasano A, Munhoz RP, Hutchison W, Cohn M, Chen R, Kalia SK, Lozano AM

Brain stimulation202135 citationsOpen Access

DOI: 10.1016/j.brs.2021.04.016 PMID: 33940243

03

Subthalamic suppression defines therapeutic threshold of deep brain stimulation in Parkinson's disease.

Milosevic L, Kalia SK, Hodaie M, Lozano A, Popovic MR, Hutchison W

Journal of neurology, neurosurgery, and psychiatry201928 citationsSenior author

DOI: 10.1136/jnnp-2019-321140 PMID: 31422369

04

Pedunculopontine Nucleus Region Deep Brain Stimulation in Parkinson Disease: Surgical Anatomy and Terminology.

Hamani C, Aziz T, Bloem BR, Brown P, Chabardes S, Coyne T, Foote K, Garcia-Rill E, Hirsch EC, Lozano AM, Mazzone PA, Okun MS, Hutchison W, Silburn P, Zrinzo L, Alam M, Goetz L, Pereira E, Rughani A, Thevathasan W, Moro E, Krauss JK

Stereotactic and functional neurosurgery2016577 citationsOpen Access

DOI: 10.1159/000449010 PMID: 27723662

05

Pedunculopontine Nucleus Region Deep Brain Stimulation in Parkinson Disease: Surgical Techniques, Side Effects, and Postoperative Imaging.

Hamani C, Lozano AM, Mazzone PA, Moro E, Hutchison W, Silburn PA, Zrinzo L, Alam M, Goetz L, Pereira E, Rughani A, Thevathasan W, Aziz T, Bloem BR, Brown P, Chabardes S, Coyne T, Foote K, Garcia-Rill E, Hirsch EC, Okun MS, Krauss JK

Stereotactic and functional neurosurgery201663 citationsOpen Access

DOI: 10.1159/000449011 PMID: 27728909

06

The Effect of General Anesthesia on the Microelectrode Recordings From Pallidal Neurons in Patients With Dystonia

Lashmi Venkatraghavan, Evgeny Rakhman, Vibhor Krishna, Francesco Sammartino, Pirjo H Manninen, William D. Hutchison

Journal of Neurosurgical Anesthesiology201528 citationsSenior author

DOI: 10.1097/ana.0000000000000200 PMID: 26083425

07

Bilateral pallidal stimulation for sargoglycan epsilon negative myoclonus

Christos Sidiropoulos, Tiago Mestre, William D. Hutchison, Elena Moro, Alejandro Valencia-Arías, Yu‐Yan Poon, Melanie Fallis, Anand I. Rughani, Suneil Kumar Kalia, Andrés M. Lozano, Anthony E. Lang

Parkinsonism & Related Disorders201420 citations

DOI: 10.1016/j.parkreldis.2014.04.017 PMID: 24812007

08

Correspondence of microelectrode mapping with magnetic resonance imaging for subthalamic nucleus procedures.

Hamani C, Richter EO, Andrade-Souza Y, Hutchison W, Saint-Cyr JA, Lozano AM

Surgical neurology200587 citations

DOI: 10.1016/j.surneu.2004.05.036 PMID: 15734516

Developing a Biologically-realistic Model-based Approach for Generating Deep Brain Stimulation Patterns

Co-investigatorCIHR2023Project Grant

Principal investigators: Lankarany, Milad; Milosevic, Luka

Keywords: Bio-Signal Processing; Closed-Loop Neuromodulation; Computational Neuroscience; Deep Brain Stimulation; In-Vivo Human Recordings; Movement Disorder; Optimal Pattern Generator; Optimization; Parkinson'S Disease; Stimulation Induced Synaptic Plasticity

$841,500

Saccade-related beta band activity in local field potentials recorded from human basal ganglia

SupervisorCIHR2010Fellowship - Priority Announcement: Dystonia (SHOPP)

Principal investigators: Yugeta, Akihiro

Keywords: Basal Ganglia; Deep Brain Stimulation; Dystonia; Globus Pallidus Interna; Limb Movement; Local Field Potential; Oscillation; Parkinson'S Disease; Saccadic Eye Movement; Subthalamic Nucleus

$45,000

Dopamine and synaptic plasticity in human substantia nigra pars reticulata

Nominated PICIHR2009Operating Grant

Principal investigators: Hutchison, William D

Keywords: Activity-Dependent Synaptic Plasticity; Deep Brain Stimulation; Field Evoked Potentials; Intraoperative Microelectrode Recording; Movement Disorders Surgery; Parkinson'S Disease

$490,745

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Lakshmikumar Venkat Raghavan and Lakshmikumar Raghavan: 194 shared papers
Alexandre Boutet and Jurgen Germann: 163 shared papers
Suneil Kalia and Alfonso Fasano: 114 shared papers
Mojgan Hodaie and Suneil Kalia: 112 shared papers
Mojgan Hodaie and Alfonso Fasano: 74 shared papers
Alfonso Fasano and Alexandre Boutet: 65 shared papers
Alfonso Fasano and Jurgen Germann: 61 shared papers
Suneil Kalia and Alexandre Boutet: 54 shared papers
Suneil Kalia and Luka Milosevic: 53 shared papers
Suneil Kalia and Jurgen Germann: 52 shared papers
Mojgan Hodaie and Alexandre Boutet: 41 shared papers
Mojgan Hodaie and Luka Milosevic: 37 shared papers
Robert Chen and Mojgan Hodaie: 28 shared papers
Robert Chen and Alfonso Fasano: 27 shared papers
Alfonso Fasano and Luka Milosevic: 25 shared papers
Mojgan Hodaie and Clement Hamani: 24 shared papers
Suneil Kalia and Clement Hamani: 21 shared papers
Suneil Kalia and Milos Popovic: 21 shared papers
Robert Chen and Suneil Kalia: 18 shared papers
Alfonso Fasano and Clement Hamani: 18 shared papers
Milos Popovic and Luka Milosevic: 17 shared papers
Robert Chen and Milos Popovic: 13 shared papers
Melanie Cohn and Alfonso Fasano: 11 shared papers
Suneil Kalia and Melanie Cohn: 8 shared papers
Mojgan Hodaie and Andres Lozano: 6 shared papers
Mojgan Hodaie and Melanie Cohn: 6 shared papers
Andres Lozano and Suneil Kalia: 6 shared papers
Andres Lozano and Alfonso Fasano: 6 shared papers
Suneil Kalia and Tiago Mestre: 5 shared papers
Suneil Kalia and Lakshmikumar Venkat Raghavan: 5 shared papers
Suneil Kalia and Lakshmikumar Raghavan: 5 shared papers
Suneil Kalia and William Hutchison: 4 shared papers
Mojgan Hodaie and William Hutchison: 3 shared papers
Tiago Mestre and Alfonso Fasano: 3 shared papers
Clement Hamani and William Hutchison: 3 shared papers
Robert Chen and Tiago Mestre: 2 shared papers
Mojgan Hodaie and Lakshmikumar Venkat Raghavan: 2 shared papers
Mojgan Hodaie and Lakshmikumar Raghavan: 2 shared papers
Andres Lozano and William Hutchison: 2 shared papers
Alfonso Fasano and William Hutchison: 2 shared papers
Milos Popovic and William Hutchison: 2 shared papers
Luka Milosevic and William Hutchison: 2 shared papers
Robert Chen and William Hutchison: 1 shared paper
Melanie Cohn and William Hutchison: 1 shared paper
Tiago Mestre and William Hutchison: 1 shared paper
Alexandre Boutet and William Hutchison: 1 shared paper
Jurgen Germann and William Hutchison: 1 shared paper
Lakshmikumar Venkat Raghavan and William Hutchison: 1 shared paper
William Hutchison and Lakshmikumar Raghavan: 1 shared paper

Department of Surgery
Department of Medicine
Department of Anesthesiology and Pain Medicine
Institute of Medical Science
Institute of Biomedical Engineering
Department of Medical Biophysics
Department of Psychology
Other

Applying for

Paper to mention

Subject: Prospective PhD student Dear Professor Hutchison, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Clinico-physiological correlates of Parkinson's disease from multi-resolution basal ganglia recordings." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]