Maud Gorbet, University of Waterloo

Research

biocompatibility flow cytometry inflammation corneal and conjunctival epithelial cells cytokines in vitro model neutrophil-bacteria interactions neutrophils

Latest papers

Phenotype of Tear Leukocytes in Seasonal Ocular Allergy and Their Potential Impacts on Ocular Surface Inflammation
Ocular Immunology and Inflammation · 2026 · senior author
Transmigrated Neutrophils on the Ocular Surface and in Other Tissues: A Narrative Review
Ocular Surface · 2026 · senior author
Design and validation of a perfusion bioreactor for long-term human bone explant culture.
JBMR plus · 2026

All 31 publications

Latest funding

Multi-parametric analysis of cells to accelerate the discovery of biological targets and advance the development of novel strategies to modulate inflammation and immunity
NSERC · 2025 · Principal investigator
$150,000
Mechanical testing of small hydrated biomaterials in fluid under controlled temperature
NSERC · 2022 · Co-investigator
$60,914
Eliminating tympanostomy, the most common surgery performed on children
SSHRC · 2022 · Co-investigator
$125,000

All 20 grants and awards

31 publications.

01

Phenotype of Tear Leukocytes in Seasonal Ocular Allergy and Their Potential Impacts on Ocular Surface Inflammation

Jin Y, Jones L, Gorbet M

Ocular Immunology and Inflammation20262 citationsSenior author

DOI: 10.1080/09273948.2026.2647163

02

Transmigrated Neutrophils on the Ocular Surface and in Other Tissues: A Narrative Review

Jin Y, Mohsenkhani S, Walker M, Jones L, Gorbet M

Ocular Surface2026Senior author

DOI: 10.1016/j.jtos.2026.04.007

03

Design and validation of a perfusion bioreactor for long-term human bone explant culture.

Zojaji M, Pageau AG, Maluckov T, Eichwalder J, Peskova M, Smith C, Athwal GS, Gorbet M, Ferreira LM, Knowles N

JBMR plus2026

DOI: 10.1093/jbmrpl/ziag081 PMID: 42181910

04

In vitro tear replenishment system: assessing drug delivery from contact lens biomaterials through corneal epithelial monolayer and multilayer under replenishment conditions

Mohammadi S, Eslami S, Jones L, Gorbet M

Drug Delivery and Translational Research20251 citationsSenior author

DOI: 10.1007/s13346-024-01746-z

05

Sperm cell empowerment: X-ray-guided magnetic fields for enhanced actuation and localization of cytocompatible biohybrid microrobots.

Magdanz V, van der Mijle Meijer JK, Ligtenberg LW, Pervez Y, LaBrash-White M, Shabani Dargah M, Mulder I, Mohsenkani S, Gorbet M, Bouzari N, Shahsavan H, Weber L, Liefers RH, Warlé MC, Khalil ISM

npj Robotics2025

DOI: 10.1038/s44182-025-00044-1 PMID: 40909862

06

Investigation of the rhythmic recruitment of tear neutrophils to the ocular surface and their phenotypes

Jin Y, Minten C, Jenkins M, Jones L, Gorbet M

Scientific Reports20247 citationsSenior author

DOI: 10.1038/s41598-024-57311-8

07

The effect of triglycerol diacrylate on the printability and properties of UV curable, bio-based nanohydroxyapatite composites.

Diederichs EV, Mondal D, Patil H, Gorbet M, Willett TL

Journal of the mechanical behavior of biomedical materials2024

DOI: 10.1016/j.jmbbm.2024.106499 PMID: 38490049

08

In vitro evaluation of bone cell response to novel 3D-printable nanocomposite biomaterials for bone reconstruction.

Haghpanah Z, Mondal D, Momenbeitollahi N, Mohsenkhani S, Zarshenas K, Jin Y, Watson M, Willett T, Gorbet M

Journal of biomedical materials research. Part A2024Senior author

DOI: 10.1002/jbm.a.37719 PMID: 38619300

09

Chitosan Grafted with Thermoresponsive Poly(di(ethylene glycol) Methyl Ether Methacrylate) for Cell Culture Applications.

Dasgupta N, Sun D, Gorbet M, Gauthier M

Polymers2023

DOI: 10.3390/polym15061515 PMID: 36987295

10

The Differential Reactive Oxygen Species Production of Tear Neutrophils in Response to Various Stimuli In Vitro

Jin Y, Dixon B, Jones L, Gorbet M

International Journal of Molecular Sciences202115 citationsSenior author

DOI: 10.3390/ijms222312899

Multi-parametric analysis of cells to accelerate the discovery of biological targets and advance the development of novel strategies to modulate inflammation and immunity

Principal investigatorNSERC2025Research Tools and Instruments

Principal investigators: Gorbet, Maud

Keywords: flow cytometry; immune response; in vitro models; biocompatibility; inflammation; cell-biomaterial interactions; leukocytes; sperm cells; fish cells; primary and stem cells

$150,000

Mechanical testing of small hydrated biomaterials in fluid under controlled temperature

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Yim, Evelyn

$60,914

Eliminating tympanostomy, the most common surgery performed on children

Co-investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: Maftoon, Nima

Keywords: Auditory mechanics; Medical device; Tympanic membrane; Soft tissue fracture; Biomaterial; Biocompatibility; Otitis media; Ear infection; Tympanostomy

$125,000

Towards an in vitro model of biocompatibility testing in the closed eye: tear film neutrophil phenotype and healthy host innate immune responses

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Gorbet, Maud

Keywords: neutrophils; corneal and conjunctival epithelial cells; in vitro model; inflammation; biocompatibility; cytokines; neutrophil-bacteria interactions; flow cytometry; ocular biomaterials

$210,000

Training in Global Biomedical Technology Research and Innovation

Co-investigatorNSERC2018Collaborative Research and Training Experience

Principal investigators: Burns, Catherine M

Keywords: biomedical imaging; commercialization; entrepreneurship; instrumentation; medical devices; prosthetics; regulation; sensors

$1,650,000

Development of biocompatibility testing and strategy for implantable biosensors

Principal investigatorNSERC2018Engage Grants Program

Principal investigators: Gorbet, Maud

$25,000

Bone-mimetic nanocomposite biomaterials for critically-sized skeletal defect reconstruction

Co-investigatorCIHR2017Project Grant

Principal investigators: Willett, Thomas

Keywords: Additive Manufacturing; Biomechanical Properties; Critically Sized Defects; Cytotoxicity; Osteoconduction; Skeletal Biomaterials; Skeletal Reconstruction; Structural Biomaterials

$665,552

Cytation Cell Imaging Multi-Mode Reader

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Jones, Lyndon

$144,236

Multiplexed Immunoassay Platform to Quantify Cytokines in Biological Samples

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Jones, Lyndon

$51,188

Upgrade of U of Waterloo's primary confocal microscope with state-of-the-art correlative microscopy for co-applicants in 11 departments

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Spafford, David

$144,912

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Systems Design Engineering
Chemical Engineering
Systems Design Engineering - University of Waterloo
Mechanical Engineering and Mechatronics
School of Optometry and Vision Science
Physics and Astronomy

Co-authors at University of Waterloo, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lyndon Jones

Chemical Engineering

7 shared papers, latest 2026

John Brash

Chemical Engineering

2 shared papers, latest 2019

Alexander Wong

Systems Design Engineering - University of Waterloo

2 shared papers, latest 2015

John Medley

Mechanical Engineering and Mechatronics

2 shared papers, latest 2015

Hamed Shahsavan

Chemical Engineering

1 shared papers, latest 2025

David Clausi

Systems Design Engineering

1 shared papers, latest 2011

Veronika Magdanz

Systems Design Engineering

1 shared papers, latest 2025

Luigina Sorbara

Physics and Astronomy

1 shared papers, latest 2021

Kostadinka Bizheva

School of Optometry and Vision Science

1 shared papers, latest 2021

Thomas Willett

Systems Design Engineering

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2025

Subject: Prospective PhD student: biocompatibility Dear Professor Gorbet, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Phenotype of Tear Leukocytes in Seasonal Ocular Allergy and Their Potential Impacts on Ocular Surface Inflammation" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Multi-parametric analysis of cells to accelerate the discovery of biological targets and advance the development of novel strategies to modulate inflammation and immunity" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]