Armen Parsyan, Western University

Research

Read how they describe their research on their Western University profile.

Breast Cancer Chemotherapy And Radiotherapy Translational Research

Latest papers

Spatial proteomic profiling reveals an association between NF1-Ras/Raf/MEK signaling and immune cell infiltration in locally advanced triple-negative breast cancer.
Translational oncology · 2026 · senior author
Emerging role of human epidermal growth factor 2-low status in the prognosis and management of triple-negative breast cancer: a narrative review.
Translational cancer research · 2026 · senior author
Pseudogenes in breast cancer pathogenesis and their clinical utility.
Critical reviews in oncology/hematology · 2026 · senior author

All 17 publications

Latest funding

Developing Magnetic Particle Imaging (MPI) Lymphography
CIHR · 2024 · Co-investigator
$677,025
High-resolution mapping of cancer immunity to predict response to therapy in HER2-positive breast cancer patients
CIHR · 2023 · Co-investigator
$62,500
Studies of Anticancer Effects of Radiation Therapy and Polo-Like Kinase 4 (PLK4) Inhibitor CFI-400945 in Triple Negative Breast Cancer
CIHR · 2022 · Nominated PI
$60,000

All 3 grants and awards

17 publications.

01

Spatial proteomic profiling reveals an association between NF1-Ras/Raf/MEK signaling and immune cell infiltration in locally advanced triple-negative breast cancer.

Bhat V, Goebel E, Postenka C, Santiago AFG, Wei Y, Brackstone M, Allan AL, Parsyan A

Translational oncology2026Senior author

DOI: 10.1016/j.tranon.2026.102934 PMID: 42520478

02

Emerging role of human epidermal growth factor 2-low status in the prognosis and management of triple-negative breast cancer: a narrative review.

Oelschlagel N, Mithoowani H, Goebel EA, Ghasemi F, Knowles S, Maciver A, Brackstone M, Parsyan A

Translational cancer research2026Senior author

DOI: 10.21037/tcr-2026-1-0370 PMID: 42591577

03

Pseudogenes in breast cancer pathogenesis and their clinical utility.

Kannampuzha I, Ghasemi F, Parsyan A

Critical reviews in oncology/hematology2026Senior author

DOI: 10.1016/j.critrevonc.2025.105078 PMID: 41371458

04

Polo-like kinase 4 (PLK4) as a therapeutic target in breast cancer.

Parsyan A, Athwal H, Bhat V, Allan AL

Carcinogenesis2025First author

DOI: 10.1093/carcin/bgaf067 PMID: 41092110

05

Artemis (DCLRE1C) Acts as a Target to Enhance Radiotherapy Response in Triple-Negative Breast Cancer.

Bhat V, Thu KL, Goncalves Santiago AF, Bonvissuto AC, Ghasemi F, Goodale D, Roes MV, Passos DT, Dick FA, Cescon DW, Allan AL, Parsyan A

Cancers2025Senior author

DOI: 10.3390/cancers17203279 PMID: 41154337

06

Investigation of effects of CFI-400945 and ionizing radiation on DNA damage response in triple-negative breast cancer.

Athwal H, Bhat V, Allan AL, Parsyan A

Translational cancer research2025Senior author

DOI: 10.21037/tcr-2024-2495 PMID: 40687253

07

Clinical Utility of IFIT Proteins in Human Malignancies.

Parsyan A, Kochiyanil A, Bonvissuto AC, Bhat V, Allan AL

Biomedicines2025First author

DOI: 10.3390/biomedicines13061435 PMID: 40564154

08

Artemis and its role in cancer.

Parsyan A, Bhat V, Athwal H, Goebel EA, Allan AL

Translational oncology2025First author

DOI: 10.1016/j.tranon.2024.102165 PMID: 39520877

09

Role of AURKB Inhibition in Reducing Proliferation and Enhancing Effects of Radiotherapy in Triple-Negative Breast Cancer.

Pellizzari S, Athwal H, Bonvissuto AC, Parsyan A

Breast cancer (Dove Medical Press)2024Senior author

DOI: 10.2147/bctt.s444965 PMID: 39006183

10

Centrosomes and associated proteins in pathogenesis and treatment of breast cancer.

Athwal H, Kochiyanil A, Bhat V, Allan AL, Parsyan A

Frontiers in oncology2024Senior author

DOI: 10.3389/fonc.2024.1370565 PMID: 38606093

Developing Magnetic Particle Imaging (MPI) Lymphography

Co-investigatorCIHR2024Project Grant

Principal investigators: Foster, Paula J

Keywords: Cancer; Imaging; Lymph Nodes; Magnetic Particle Imaging; Nanoparticles

$677,025

High-resolution mapping of cancer immunity to predict response to therapy in HER2-positive breast cancer patients

Co-investigatorCIHR2023CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer

Principal investigators: Dumeaux, Vanessa

Keywords: Genomics Approaches; Targets And Biomarkers; Translational Research

$62,500

Studies of Anticancer Effects of Radiation Therapy and Polo-Like Kinase 4 (PLK4) Inhibitor CFI-400945 in Triple Negative Breast Cancer

Nominated PICIHR2022CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer

Principal investigators: Parsyan, Armen

Keywords: Breast Cancer; Chemotherapy And Radiotherapy; Translational Research

$60,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Surgery
Surgery
School of Epidemiology and Public Health
Department of Medicine
Family Medicine
General Surgery
College of Community and Global Health
Other

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Sarah Knowles

Department of Surgery

2 shared papers, latest 2026

David Moher

School of Epidemiology and Public Health

2 shared papers, latest 2021

Kelly Vogt

General Surgery

1 shared papers, latest 2023

Axel BENHAMED

Family Medicine and Emergency Medicine

1 shared papers, latest 2023

Jordan Feld

School of Nursing

1 shared papers, latest 2023

Jennifer Flemming

School of Nursing

1 shared papers, latest 2023

Jennifer Flemming

Transplant Program

1 shared papers, latest 2023

Laura Dawson

Department of Radiation Oncology

1 shared papers, latest 2023

Steven Gallinger

Medical Biophysics

1 shared papers, latest 2023

Philip Devereaux

Health Research Methods, Evidence, and Impact

1 shared papers, latest 2023

Girish Kulkarni

Toronto General Research Institute

1 shared papers, latest 2023

Dean Fergusson

Department of Medicine

1 shared papers, latest 2023

Dean Eurich

Cardiology

1 shared papers, latest 2023

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2022

Subject: Prospective PhD student: Breast Cancer Dear Professor Parsyan, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Spatial proteomic profiling reveals an association between NF1-Ras/Raf/MEK signaling and immune cell infiltration in locally advanced triple-negative breast cancer." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Studies of Anticancer Effects of Radiation Therapy and Polo-Like Kinase 4 (PLK4) Inhibitor CFI-400945 in Triple Negative Breast Cancer" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Armen Parsyan

Research

Latest papers

Latest funding

Spatial proteomic profiling reveals an association between NF1-Ras/Raf/MEK signaling and immune cell infiltration in locally advanced triple-negative breast cancer.

Emerging role of human epidermal growth factor 2-low status in the prognosis and management of triple-negative breast cancer: a narrative review.

Pseudogenes in breast cancer pathogenesis and their clinical utility.

Polo-like kinase 4 (PLK4) as a therapeutic target in breast cancer.

Artemis (DCLRE1C) Acts as a Target to Enhance Radiotherapy Response in Triple-Negative Breast Cancer.

Investigation of effects of CFI-400945 and ionizing radiation on DNA damage response in triple-negative breast cancer.

Clinical Utility of IFIT Proteins in Human Malignancies.

Artemis and its role in cancer.

Role of AURKB Inhibition in Reducing Proliferation and Enhancing Effects of Radiotherapy in Triple-Negative Breast Cancer.

Centrosomes and associated proteins in pathogenesis and treatment of breast cancer.

Developing Magnetic Particle Imaging (MPI) Lymphography

High-resolution mapping of cancer immunity to predict response to therapy in HER2-positive breast cancer patients

Studies of Anticancer Effects of Radiation Therapy and Polo-Like Kinase 4 (PLK4) Inhibitor CFI-400945 in Triple Negative Breast Cancer

Frequent collaborators

Muriel Brackstone

Sarah Knowles

David Moher

Kimberly LeBlanc

Gary Groot

Kelly Vogt

Husein Moloo

Axel BENHAMED

Pierre-Gilles Blanchard

Anand Ghanekar

Gonzalo Sapisochin

Michael Verret

Manoj Lalu

Susan Brogly

Karineh Kazazian

Jordan Feld

Jennifer Flemming

Jennifer Flemming

Laura Dawson

Steven Gallinger

Lawrence Gillman

Michael Verret

Philip Devereaux

Mohit Bhandari

Sameer Parpia

Joanna Dionne

Cagla Eskicioglu

Bradley Allan Petrisor

Timothy Whelan

Edward Passos

John Agzarian

Paul Engels

Ilun Yang

Dennis Hong

Bobby Shayegan

Mark Norman Levine

Girish Kulkarni

Natalie Coburn

Dean Fergusson

Dean Eurich