Terry-Lynn Young, Western University

Research

Read how they describe their research on their Western University profile.

Apolipoprotein E Cognition Epidemiology Genetics Hearing Senses Social Isolation Vision

Latest papers

Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis.
International journal of molecular sciences · 2026 · senior author
Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses.
European journal of human genetics : EJHG · 2023 · senior author
Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene.
Human genetics · 2022 · senior author

All 4 publications

Latest funding

Identifying novel genes causing otosclerosis, the most common cause of progressive hearing loss in Caucasians worldwide, using Newfoundland's founder population.
CIHR · 2010 · Nominated PI
$250,554
Using a genetic isolate to identify novel genes causing otosclerosis, the most common cause of progressive hearing loss in Caucasians worldwide.
CIHR · 2010 · Supervisor
$45,000
Determining the genetic etiology of congenital hearing loss in families from Newfoundland and Labrador
CIHR · 2009 · Supervisor
$17,500

All 3 grants and awards

4 publications.

01

Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis.

Benteau T, Abdelfatah N, Griffin A, Penney C, Hu P, Stanton SG, Zhai G, Maheu M, French CR, Young TL

International journal of molecular sciences2026Senior author

DOI: 10.3390/ijms27114985 PMID: 42278511

02

Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses.

Singh S, Penney C, Griffin A, Woodland G, Werdyani S, Benteau TA, Abdelfatah N, Squires J, King B, Houston J, Dyer MJ, Roslin NM, Vincent D, Marquis P, O'Rielly DD, Hodgkinson K, Burt T, Baker A, Stanton SG, Young TL

European journal of human genetics : EJHG2023Senior author

DOI: 10.1038/s41431-023-01358-0 PMID: 37072551

03

Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene.

Pater JA, Penney C, O'Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble A, Avraham KB, Stanton SG, Young TL

Human genetics2022Senior author

DOI: 10.1007/s00439-022-02444-x PMID: 35278131

04

A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect.

Pater JA, Benteau T, Griffin A, Penney C, Stanton SG, Predham S, Kielley B, Squires J, Zhou J, Li Q, Abdelfatah N, O'Rielly DD, Young TL

Human genetics2017Senior author

DOI: 10.1007/s00439-016-1746-7 PMID: 27838790

Identifying novel genes causing otosclerosis, the most common cause of progressive hearing loss in Caucasians worldwide, using Newfoundland's founder population.

Nominated PICIHR2010Operating Grant - PA: Regional Partnership Program - Newfoundland and Labrador

Principal investigators: Young, Terry-Lynn

Keywords: Family And Population Studies; Gene Mapping And Cloning; Gene-Gene Interactions; Genetics Of Deafness; Genotype-Phenotype Correlation; Isolated Population

$250,554

Using a genetic isolate to identify novel genes causing otosclerosis, the most common cause of progressive hearing loss in Caucasians worldwide.

SupervisorCIHR2010Fellowship - PA: Regional Partnership Program - Newfoundland & Labrador

Principal investigators: Abdelfatah, Nelly F

Keywords: Genetics; Hearing Loss; Mutation Screening

$45,000

Determining the genetic etiology of congenital hearing loss in families from Newfoundland and Labrador

SupervisorCIHR2009Master's Award: Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Squires, Jessica S

Keywords: Congenital; Etiology; Family And Population Studies; Founder Population; Gene Mapping; Genetics; Hearing Loss; Heredity; Newfoundland And Labrador; Novel Gene Discovery

$17,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biomedical Sciences
School of Communication Sciences and Disorders

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Guangju Zhai

Biomedical Sciences

1 shared papers, latest 2026

Touati Benoukraf

Biomedical Sciences

1 shared papers, latest 2022

Write to this professor

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Applying for

Paper to mention

Subject: Prospective PhD student: Apolipoprotein E Dear Professor Young, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]