This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a York University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Widespread omission of aptamer-target binding verification in aptasensor development: Consequences for sensor performance and the need for a Kd gate.
Biosensors & bioelectronics · 2026
The evolving logic of biocatalyzed nucleic acid synthesis.
Current opinion in chemical biology · 2026 · senior author
Generation of Diversely Functionalized DNA Libraries Using Ligase-Catalyzed Oligonucleotide Polymerization (LOOPER).
Methods in molecular biology (Clifton, N.J.) · 2026 · senior author
Latest funding
- $150,000
An Isothermal Titration Calorimeter for Characterizing the Affinity and Thermodynamics of Biomolecular Interactions
NSERC · 2025 · Co-investigator
- $450,000
Technology-Enhanced Pharmaceutical Discovery (TEPD)
NSERC · 2023 · Co-investigator
- $229,200
Exploring the Chemical Diversity of Nucleic Acids
NSERC · 2023 · Principal investigator
25 publications.
Widespread omission of aptamer-target binding verification in aptasensor development: Consequences for sensor performance and the need for a Kd gate.
Krylov SN, Krylova SM, Le ATH, Johnson PE, Hili R, Wilson DJ, Kim SB, Stovall GM, Xu G, Dzantiev BB, DeRosa M, Bueno PR, Dauphin-Ducharme P, Tanner JA, Whitehouse WL, Zhao Q, Zhu JJ, Crous A, Ferapontova E
The evolving logic of biocatalyzed nucleic acid synthesis.
Rustico L, Hili R
Generation of Diversely Functionalized DNA Libraries Using Ligase-Catalyzed Oligonucleotide Polymerization (LOOPER).
Khamissi N, Rustico L, Hili R
Ligase-Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase.
Khamissi N, Rustico L, Hili R
Ligase-catalyzed transcription and reverse-transcription of XNA-containing nucleic acid polymers using T3 DNA ligase.
Khamissi N, Korfmann C, Chaudhry A, Hili R
PhOxi-seq Detects Enzyme-Dependent m2G in Multiple RNA Types.
Klimontova M, Chung KCK, Zhang H, Kouzarides T, Bannister AJ, Hili R
THUMPD3 regulates alternative splicing of ECM transcripts in human lung cancer cells and promotes proliferation and migration.
Klimontova M, Zhang H, Campos-Laborie F, Webster N, Andrews B, Kim Chung KC, Hili R, Kouzarides T, Bannister AJ
Photoredox-catalysed hydroaminoalkylation of on-DNA N-arylamines.
Mahdavi-Amiri Y, Hu MSJ, Frias N, Movahedi M, Csakai A, Marcaurelle LA, Hili R
PhOxi-Seq: Single-Nucleotide Resolution Sequencing of N2-Methylation at Guanosine in RNA by Photoredox Catalysis.
Chung Kim Chung K, Mahdavi-Amiri Y, Korfmann C, Hili R
How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands.
Le ATH, Krylova SM, Beloborodov SS, Wang TY, Hili R, Johnson PE, Li F, Veedu RN, Belyanskaya S, Krylov SN
An Isothermal Titration Calorimeter for Characterizing the Affinity and Thermodynamics of Biomolecular Interactions
Principal investigators: Johnson, Philip
Keywords: isothermal titration calorimetry; calorimetry; aptamers; ligand binding; dna-small molecule interactions; protein-protein interactions; dna encoded libraries; biomolecular interactions
Technology-Enhanced Pharmaceutical Discovery (TEPD)
Principal investigators: Krylov, Sergey SN
Keywords: capillary electrophoresis; combinatorial libraries; dna-encoded library technology; drug discovery; high-throughput screening; hit-to-lead process; hit validation; mass spectrometry; vaccine development
Exploring the Chemical Diversity of Nucleic Acids
Principal investigators: Hili, Ryan
Keywords: nucleic acids; rna; dna; aptamers; epitranscriptomics; sequencing; post-transcriptional modifications; xna; dna-encoded libraries; probes
Single-Nucleotide Sequencing of N6-methyladenosine in SARS-CoV2 RNA (COVID-19)_x000d_ _x000d_ _x000d_ _x000d_
Principal investigators: Hili, Ryan
Expanding the Chemistry of Nucleic Acids for the Discovery of Molecular Function
Principal investigators: Hili, Ryan
Technologies to enable automated manufacturing of validated pharmaceutical hits_x000d_ _x000d_
Principal investigators: Krylov, Sergey
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Maria DeRosa and Philippe Dauphin Ducharme: 1 shared paper
- Maria DeRosa and Ryan Hili: 1 shared paper
- Philippe Dauphin Ducharme and Ryan Hili: 1 shared paper
- Feng Li and Ryan Hili: 1 shared paper
- Chemistry
- Chimie
Co-authors at York University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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