Faculty profile

John Antoniou

ResearcherExperimental SurgeryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

John Antoniou

Researcher

Experimental Surgery

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
21 publications in the last five years, latest in 2026.
Senior (last) author on 11 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

111

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Tissue Engineering Link N Cartilage Repair Disease-Modifying Osteoarthritis Drug Disc Degeneration Osteoarthritis Vgef Receptor Inhibitor Disease-Modifying Drug

Latest papers

Intraoperative femoral fracture during uncemented total hip arthroplasty: does the stem length matter?
Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2026 · senior author
Does Stem Design Affect the Incidence of Periprosthetic Femoral Fractures in Arthroplasty for Femoral Neck Fractures? A Secondary Analysis of the HEALTH Trial
Journal of Arthroplasty · 2025 · senior author
Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration.
Biomolecules · 2025

All 111 publications

Latest funding

Integrative Strategies for Osteoarthritis Therapy: Combining Nanoparticle-based VEGF Receptor Inhibition with Link N Peptide Applications
CIHR · 2025 · Principal investigator
$944,775
Engineered Stem Cell Membrane-Derived Vesicles for Modulating Dysregulated TGF-Beta Signaling in Targeted Osteoarthritis Gene Therapy
CIHR · 2025 · Co-investigator
$948,600
Small molecule inhibitor of IL-1b signaling in degenerative disc disease
CIHR · 2022 · Principal investigator
$734,400

All 12 grants and awards

111 publications.

Intraoperative femoral fracture during uncemented total hip arthroplasty: does the stem length matter?

Almazrua I, Dimitriou D, Staunton P, Zukor D, Huk O, Antoniou J

Hip international : the journal of clinical and experimental research on hip pathology and therapy2026Senior author

DOI: 10.1177/11207000251404013 PMID: 41507131

Does Stem Design Affect the Incidence of Periprosthetic Femoral Fractures in Arthroplasty for Femoral Neck Fractures? A Secondary Analysis of the HEALTH Trial

Megaloikonomos PD, Nowak L, Shehata M, Sprague S, Bzovsky S, Epure LM, De Petrillo G, Caron C, Laggis G, Huk OL

Journal of Arthroplasty20257 citationsSenior author

DOI: 10.1016/j.arth.2025.02.036

Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration.

Grant MP, Alad M, Yousef F, Epure LM, Antoniou J, Mwale F

Biomolecules2025

DOI: 10.3390/biom15040603 PMID: 40305345

Social Media Discussions About Robotic Total Knee Arthroplasty: Cross-Sectional Analysis.

Desgagné C, Levett JJ, Elkaim LM, Antoniou J

JMIR infodemiology2025Senior author

DOI: 10.2196/69883 PMID: 41066621

Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation.

Alad M, Yousef F, Epure LM, Lui A, Grant MP, Merle G, Eliopoulos N, Barralet J, Antoniou J, Mwale F

Biomolecules2025

DOI: 10.3390/biom15060874 PMID: 40563514

Long-term impact of physical activity and sports participation on implant integrity in resurfacing hip arthroplasty versus total hip arthroplasty: a systematic review.

Levett JJ, Alnasser A, Teoli A, Martel S, Robbins S, Huk OL, Zukor DJ, Antoniou J

Hip international : the journal of clinical and experimental research on hip pathology and therapy2025Senior author

DOI: 10.1177/11207000251315941 PMID: 39949071

Immunoglobulin A Nephropathy in a Patient With Bilateral Metal-on-Metal Hip Arthroplasty.

Levett JJ, Alatassi R, Huk OL, Antoniou J

Arthroplasty today2024Senior author

DOI: 10.1016/j.artd.2024.101407 PMID: 38946922

Inter-segment coordination amplitude and variability during gait in patients with knee osteoarthritis and asymptomatic adults.

Robbins SM, Teoli A, Huk OL, Zukor DJ, Antoniou J

Gait & posture2024Senior author

DOI: 10.1016/j.gaitpost.2023.10.024 PMID: 37923641

Impact of combined lumbar spine fusion and total hip arthroplasty on spine, pelvis, and hip kinematics during a sit to stand task.

Robbins SM, Tyrpenou E, Lee S, Ippersiel P, Antoniou J

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology2024Senior author

DOI: 10.1016/j.jelekin.2024.102871 PMID: 38460219

Integrative Strategies for Osteoarthritis Therapy: Combining Nanoparticle-based VEGF Receptor Inhibition with Link N Peptide Applications

Principal investigatorCIHR2025Project Grant

Principal investigators: Mwale, Fackson; Antoniou, John

Keywords: Cartilage Repair; Disease-Modifying Osteoarthritis Drug; Link N; Osteoarthritis; Tissue Engineering; Vgef Receptor Inhibitor

$944,775

Engineered Stem Cell Membrane-Derived Vesicles for Modulating Dysregulated TGF-Beta Signaling in Targeted Osteoarthritis Gene Therapy

Co-investigatorCIHR2025Project Grant

Principal investigators: Tabrizian, Maryam

Keywords: Cartilage Regeneration; Extracellular Vesicle Mimetic; Immunomodulation; Mesenchymal Stem Cell-Derived Nanoghosts; Multifactorial Osteoarthritis Treatment; Osteoarthritis Therapy; Preclinical Osteoarthritis Mouse Models; Subchondral Bone Regeneration; Targeted Gene Therapy; Tgf-Beta Signalling In Osteoarthritis

$948,600

Small molecule inhibitor of IL-1b signaling in degenerative disc disease

Principal investigatorCIHR2022Project Grant

Principal investigators: Mwale, Fackson; Antoniou, John

Keywords: Disc Degeneration; Disease-Modifying Drug; Link N; Low Back Pain; Tissue Engineering

$734,400

Role of Link N in Osteoarthritis

Nominated PICIHR2021Project Grant

Principal investigators: Antoniou, John; Mwale, Fackson

Keywords: Cartilage Repair; Disease-Modifying Osteoarthritis Drug; Link N; Osteoarthritis,; Tissue Engineering

$699,975

Injectable bioactive hydrogel for the regeneration of intervertebral disc

Co-investigatorNSERC2017Collaborative Health Research Projects

Principal investigators: Lerouge, Sophie

$298,386

Regulation of TGF-beta action in chondrocytes: signaling via ALK1 versus ALK5 pathways

Co-investigatorCIHR2016Project Grant

Principal investigators: Philip, Anie

Keywords: Alk1; Alk5; Cartilage; Cd109; Endoglin; Osteoarthritis; Tgf-Beta

$630,715

Short Link N as a therapeutic agent for intervertebral disc degeneration.

Nominated PICIHR2016Project Grant

Principal investigators: Antoniou, John; Mwale, Fackson

Keywords: Disc Degeneration; Intervertebral Disc; Mesenchymal Stem Cells; Proteoglycans; Tissue Engineering

$749,211

Injectable bioactive hydrogel for the regeneration of intervertebral disc

Principal investigatorCIHR2016Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Lerouge, Sophie; Antoniou, John; Mwale, Fackson; Wagnac, Eric

Keywords: Animal Model; Chitosan; Injectable Hydrogel; Intervertebral Disk; Mechanical Characterization; Nucleus Pulposus; Peptide; Stem Cells; Tissue Repair

$298,387

Regulation of TGF-beta action in chondrocytes: signaling via ALK1 versus ALK5 pathways

Co-investigatorCIHR2015Operating Grant

Principal investigators: Philip, Anie

Keywords: Alk1; Animal Models; Cd109; Endoglin; Osteoarthritis; Tgf-Beta

$100,000

Biomechanical factors in knee osteoarthritis progression: the impact of gait differences between primary and secondary knee osteoarthritis

Co-investigatorCIHR2014Operating Grant - PA: IMHA - New Invest.- Musculoskeletal Health Bridge Funding

Principal investigators: Robbins, Shawn M

Keywords: Cartilage; Electromyography; Gait; Kinematics; Kinetics; Knee Osteoarthritis; Ligament; Magnetic Resonance Imaging; Motion Analysis

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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John Antoniou

Research

Latest papers

Latest funding

Intraoperative femoral fracture during uncemented total hip arthroplasty: does the stem length matter?

Does Stem Design Affect the Incidence of Periprosthetic Femoral Fractures in Arthroplasty for Femoral Neck Fractures? A Secondary Analysis of the HEALTH Trial

Link N Directly Targets IL-1&#x3b2; to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration.

Social Media Discussions About Robotic Total Knee Arthroplasty: Cross-Sectional Analysis.

Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation.

Long-term impact of physical activity and sports participation on implant integrity in resurfacing hip arthroplasty versus total hip arthroplasty: a systematic review.

Immunoglobulin A Nephropathy in a Patient With Bilateral Metal-on-Metal Hip Arthroplasty.

Similar complication and readmission rates following simultaneous versus staged bilateral total hip arthroplasty.

Inter-segment coordination amplitude and variability during gait in patients with knee osteoarthritis and asymptomatic adults.

Impact of combined lumbar spine fusion and total hip arthroplasty on spine, pelvis, and hip kinematics during a sit to stand task.

Injectable bioactive hydrogel for the regeneration of intervertebral disc

Frequent collaborators

Fackson Mwale

Peter Roughley

Michael Tanzer

Maryam Tabrizian

Rahul Gawri

Pierre-Luc Girard-Lauriault

Lisbet Haglund

Jean Ouellet

Sheila Laverty

Sophie Lerouge

Geraldine Merle

Casimiro Gerarduzzi

Jake Barralet

Mihaela Iordanova

Gordon Guyatt

Diane Heels-Ansdell

Victoria Avram

Sheila Ann Sprague

Caroline Hoemann

Shawn Robbins

Lawrence Joseph

Ajay Manjoo

Kim Madden

Philip Devereaux

Mohit Bhandari

Stephen Walter

Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration.