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Research
Latest papers
Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease.
Frontiers in pharmacology · 2022
Temporary transvenous diaphragm pacing vs. standard of care for weaning from mechanical ventilation: study protocol for a randomized trial.
Trials · 2019
Autophagy and skeletal muscles in sepsis.
PloS one · 2012
Latest funding
- $1,055,700
The role of trained macrophages in dystrophic diaphragm pathology
CIHR · 2024 · Nominated PI
- $210,000
Trained immunity, macrophages and muscle stem cells in dystrophic respiratory muscle
CIHR · 2024 · Supervisor
- $442,861
COVID-19 pandemic effects on outcomes of patients in a provincial home ventilation program
CIHR · 2021 · Co-investigator
4 publications.
Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease.
Centorame A, Dumut DC, Youssef M, Ondra M, Kianicka I, Shah J, Paun RA, Ozdian T, Hanrahan JW, Gusev E, Petrof B, Hajduch M, Pislariu R, De Sanctis JB, Radzioch D
Temporary transvenous diaphragm pacing vs. standard of care for weaning from mechanical ventilation: study protocol for a randomized trial.
Evans D, Shure D, Clark L, Criner GJ, Dres M, de Abreu MG, Laghi F, McDonagh D, Petrof B, Nelson T, Similowski T
Autophagy and skeletal muscles in sepsis.
Mofarrahi M, Sigala I, Guo Y, Godin R, Davis EC, Petrof B, Sandri M, Burelle Y, Hussain SN
Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase.
Mofarrahi M, Brandes RP, Gorlach A, Hanze J, Terada LS, Quinn MT, Mayaki D, Petrof B, Hussain SN
The role of trained macrophages in dystrophic diaphragm pathology
Principal investigators: Petrof, Basil J
Keywords: Chemokines; Diaphragm; Epigenetics; Innate Immunity; Macrophages; Muscle Contractility; Muscle Fibrosis; Muscular Dystrophy; Respiratory Failure; Trained Immunity
Trained immunity, macrophages and muscle stem cells in dystrophic respiratory muscle
Principal investigators: Deprez, Alyson
Keywords: Autophagy; Diaphragm; Innate Immunity; Macrophages; Muscle Dystrophy; Muscle Fibrosis; Muscle Stem Cells; Respiratory Failure; Trained Immunity
COVID-19 pandemic effects on outcomes of patients in a provincial home ventilation program
Principal investigators: Kaminska, Marta
Keywords: Access To Care; Bpap; Mortality; Non-Invasive Ventilation
Novel therapies for diaphragm failure in muscular dystrophy
Principal investigators: Petrof, Basil J
Keywords: Autophagy; Chemokines; Diaphragm; Innate Immunity; Macrophages; Muscle Contractility; Muscle Fibrosis; Muscular Dystrophy; Respiratory Failure; Trained Immunity
Understanding the basis of diaphragmatic weakness in critical illness
Principal investigators: Petrof, Basil J
Keywords: Critical Illness Myopathy; Cytokines; Diaphragm Function; Mechanical Ventilation; Mitochondria; Muscle Atrophy; Muscle Injury; Muscle Physiology; Muscle Regeneration; Sepsis
Canadian Sepsis Research Network: Improving CareBefore, During and After Sepsis
Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Henry, Bonnie J; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Ansermino, John M; Barrett, Kali A; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan
Keywords: Biomarkers; Diabetes; Health Economics; Health Literacy; Health Services; Immune Endotypes; Knowledge Transfer; Population Health; Precision Medicine; Sepsis
Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis.
Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Schwartz, Brian; Ansermino, John M; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Loubani, Osama; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan
Keywords: Biomarkers; Diabetes And Obesity; Endotypes; Health Economics; Health Literacy; Health Services; Knowledge Transfer; Population Health; Precision Medicine; Sepsis
Novel strategies for treating respiratory muscle failure in muscular dystrophy
Principal investigators: Petrof, Basil J
Keywords: Chemokines; Diaphragm; Innate Immunity; Macrophages; Mitochondrial Function; Muscle Contractility; Muscle Fibrosis; Muscular Dystrophy; Oxidative Stress; Respiratory Failure
Ventilator-induced diaphragmatic dysfunction.
Principal investigators: Petrof, Basil J
Keywords: Diaphragm; Mechanical Ventilation; Mitochondria; Muscle Contractility; Muscle Weakness And Wasting
Strategies for therapy of respiratory muscle failure in muscular dystrophy.
Principal investigators: Petrof, Basil J
Keywords: Chemokines; Diaphragm Function; Duchenne Muscular Dystrophy; Innate Immunity; Macrophages; Muscle Physiology; Muscle Regeneration; Toll Like Receptors
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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