Faculty profile

Danuta Radzioch

ResearcherBiomedical EngineeringMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Danuta Radzioch

Researcher

Biomedical Engineering

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
14 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2023.
Supervised 2 trainees who won CIHR awards, most recently in 2012.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

6-Bromo-Indirubin-3'-Oxime (6bio)Advanced Melanoma Bacterial Colonization And Biodistribution Characterization Of The Nanoplex And Carrier Systems Copper Diethyldithiocarbamate (Cuet)Engineered Msr-1bacteria-Lpn Carrier Immunotherapy In-Vitro Immunomodulatory Effect Using Melanoma Cell Lines

Latest papers

Overcoming Resistance: Targeting Survivin-Driven Apoptotic Resistance Restores Irinotecan Sensitivity in TP53-Mutant Colorectal Cancer.
Cancers · 2026 · senior author
Impact of ΔF508 CFTR mutation on diaphragm function during acute inflammation.
American journal of physiology. Cell physiology · 2026
From Excision to Immunity: The Full Spectrum of Modern Melanoma Treatments.
Cancers · 2026 · senior author

All 80 publications

Latest funding

Engineering bacteria-based nanoplexes for melanoma immunomodulation
CIHR · 2023 · Principal investigator
$1,002,150
Defining the role of fetal reprogramming in the gut epithelium in health and disease.
CIHR · 2022 · Co-investigator
$749,700
Genetic Dissection of Phenotypes Defining Susceptibility to Allergic Asthma: Airway Hyperresponsiveness and Atopy
CIHR · 2012 · Supervisor
$105,000

All 9 grants and awards

80 publications.

Overcoming Resistance: Targeting Survivin-Driven Apoptotic Resistance Restores Irinotecan Sensitivity in TP53-Mutant Colorectal Cancer.

Dumut DC, Xu YZ, Verelli D, Das V, Hajduch M, De Sanctis JB, Radzioch D

Cancers2026Senior author

DOI: 10.3390/cancers18162687 PMID: 42649998

Impact of ΔF508 CFTR mutation on diaphragm function during acute inflammation.

Ostadan F, Gusev E, Liang F, De Sanctis JB, Radzioch D, Petrof BJ

American journal of physiology. Cell physiology2026

DOI: 10.1152/ajpcell.00018.2026 PMID: 42360227

From Excision to Immunity: The Full Spectrum of Modern Melanoma Treatments.

Murugesan V, Thuraisingam T, Radzioch D

Cancers2026Senior author

DOI: 10.3390/cancers18132043 PMID: 42449588

Liposome-Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6-Bromo-Indirubin-3'-Oxime Enable the Treatment of Refractive Melanoma.

Paun RA, Li L, Mouncef A, Radzioch D, Tabrizian M

Small (Weinheim an der Bergstrasse, Germany)2025

DOI: 10.1002/smll.202409012 PMID: 40317886

Specialized Pro-Resolving Lipid Mediators in Pulmonary Diseases: Molecular and Therapeutic Implications.

Ortega Á, Duran P, Garrido B, Manzano A, Navarro C, Silva A, Rojas M, De Sanctis JB, Radzioch D, Rivera-Porras D, Paredes CS, Bermúdez V

Molecules (Basel, Switzerland)2025

DOI: 10.3390/molecules30102212 PMID: 40430385

Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis.

Dumut DC, Hajduch M, Zacharias AM, Duan Q, Frydrych I, Rozankova Z, Popper M, Garic D, Paun RA, Centorame A, Shah J, Mistrik M, Dzubak P, De Sanctis JB, Radzioch D

Frontiers in immunology2025Senior author

DOI: 10.3389/fimmu.2025.1491450 PMID: 40013140

Bacterial hitchhiking with drug-loaded nanoparticles as a drug delivery strategy for cancer immunotherapy.

Paun RA, Dumut DC, Li L, Radzioch D, Tabrizian M

npj biomedical innovations2025

DOI: 10.1038/s44385-024-00006-6 PMID: 42032168

Efficacy and safety of LAU-7b in a Phase 2 trial in adults with cystic fibrosis.

Konstan MW, Polineni D, Chmiel JF, Bilodeau L, Middleton PG, Matouk E, Houle JM, Pislariu R, Colin P, Kianicka I, Potvin D, Radzioch D, Kotsimbos T, Zuckerman JB, Nasr SZ, Liou TG, Lands LC, study Investigators

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2025

DOI: 10.1016/j.jcf.2024.07.004 PMID: 38987119

CRISPR/Cas9 bioluminescence-based assay for monitoring CFTR trafficking to the plasma membrane.

Ondra M, Lenart L, Centorame A, Dumut DC, He A, Zaidi SSZ, Hanrahan JW, De Sanctis JB, Radzioch D, Hajduch M

Life science alliance2024

DOI: 10.26508/lsa.202302045 PMID: 37918963

Western Blotting with Fast SDS-PAGE and Semi-Dry Protein Transfer.

Garić D, Dumut DC, Centorame A, Radzioch D

Current protocols2023Senior author

DOI: 10.1002/cpz1.833 PMID: 37462371

Engineering bacteria-based nanoplexes for melanoma immunomodulation

Principal investigatorCIHR2023Project Grant

Principal investigators: Tabrizian, Maryam; Radzioch, Danuta

Keywords: 6-Bromo-Indirubin-3'-Oxime (6bio); Advanced Melanoma; Bacterial Colonization And Biodistribution; Characterization Of The Nanoplex And Carrier Systems; Copper Diethyldithiocarbamate (Cuet); Engineered Msr-1bacteria-Lpn Carrier; Immunotherapy; In-Vitro Immunomodulatory Effect Using Melanoma Cell Lines; Investigation Of Immune Response In Relevant Mouse Models; Lipid-Polymer Cuet/6bio Nanoplexes (Lnp)

$1,002,150

Defining the role of fetal reprogramming in the gut epithelium in health and disease.

Co-investigatorCIHR2022Project Grant

Principal investigators: Gregorieff, Alex

Keywords: Colorectal Cancer; Conditional Ko Mice; Fetal Gut Development; Fetal Reprogramming; Hippo Signaling; Intestinal Regeneration; Intestinal Stem Cell; Organoids; Tgf-Beta Signaling; Wnt Signaling

$749,700

Genetic Dissection of Phenotypes Defining Susceptibility to Allergic Asthma: Airway Hyperresponsiveness and Atopy

SupervisorCIHR2012Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Kanagaratham, Cynthia

Keywords: Airway Hyperresponsiveness; Allergy; Asthma; Atopy; Computational Biology; Genetic Mapping; Hypersensitivity; Linkage; Recombinant Congenic Strains

$105,000

Genetic and epigenetic control of the ZPBP2/ORMDL3/GSDMB domain and susceptibility to asthma

Co-investigatorCIHR2011Operating Grant

Principal investigators: Naumova, Anna K

Keywords: Chromatin Structure; Cildhood Asthma; Epigenetics; Genetic Variation; Transcriptional Regulation

$716,290

Genetic Dissection of Airway Hyperresponsiveness and Susceptibility to Allergic Asthma

Nominated PICIHR2010Operating Grant

Principal investigators: Radzioch, Danuta

Keywords: Allergic Asthma; Asthma Phenotypes; Candidate Genes; Gene Mapping; Genetics Of Asthma; Recombinant Strains

$926,321

Genetic Dissection of Airway Hyperresponsiveness and Susceptibility to Allergic Asthma

Nominated PICIHR2009Operating Grant - PA: Institute of Genetics (Bridge Funding)

Principal investigators: Radzioch, Danuta

Keywords: Allergic Asthma; Asthma Phenotypes; Candidate Genes; Gene Mapping; Genetics Of Asthma; Recombinant Strains

$100,000

Dynamic metabolic changes in cystic fibrosis induced by treatment with fenretinide

SupervisorCIHR2008Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Wojewodka, Gabriella

Keywords: Ceramide; Cystic Fibrosis; Fatty Acids; Gene/Protein Expression Analysis; Infection; Macrophages; Mouse Model; Pseudomonas Aeruginosa; Sirna; Sphingomyelinase

$105,000

Posttranscriptional regulation of gene expression

Principal investigatorNSERC2005Discovery Grants Program - Individual

Principal investigators: Radzioch, Danuta

$90,000

Posttranscriptional regulation of gene expression by RNA-binding proteins in activated macrophages

Principal investigatorNSERC2001Discovery Grants Program - Individual

Principal investigators: Radzioch, Danuta

$120,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Danuta Radzioch

Research

Latest papers

Latest funding

Overcoming Resistance: Targeting Survivin-Driven Apoptotic Resistance Restores Irinotecan Sensitivity in TP53-Mutant Colorectal Cancer.

Impact of &#x394;F508 CFTR mutation on diaphragm function during acute inflammation.

From Excision to Immunity: The Full Spectrum of Modern Melanoma Treatments.

Liposome-Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6-Bromo-Indirubin-3'-Oxime Enable the Treatment of Refractive Melanoma.

Specialized Pro-Resolving Lipid Mediators in Pulmonary Diseases: Molecular and Therapeutic Implications.

Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis.

Bacterial hitchhiking with drug-loaded nanoparticles as a drug delivery strategy for cancer immunotherapy.

Efficacy and safety of LAU-7b in a Phase 2 trial in adults with cystic fibrosis.

CRISPR/Cas9 bioluminescence-based assay for monitoring CFTR trafficking to the plasma membrane.

Western Blotting with Fast SDS-PAGE and Semi-Dry Protein Transfer.

Engineering bacteria-based nanoplexes for melanoma immunomodulation

Defining the role of fetal reprogramming in the gut epithelium in health and disease.

Genetic Dissection of Phenotypes Defining Susceptibility to Allergic Asthma: Airway Hyperresponsiveness and Atopy

Genetic and epigenetic control of the ZPBP2/ORMDL3/GSDMB domain and susceptibility to asthma

Genetic Dissection of Airway Hyperresponsiveness and Susceptibility to Allergic Asthma

Genetic Dissection of Airway Hyperresponsiveness and Susceptibility to Allergic Asthma

Dynamic metabolic changes in cystic fibrosis induced by treatment with fenretinide

Posttranscriptional regulation of gene expression

Posttranscriptional regulation of gene expression by RNA-binding proteins in activated macrophages

Frequent collaborators

Dao Nguyen

Maryam Tabrizian

Simon Rousseau

Samuel David

Andrea Benedetti

Andrea Benedetti

Maziar Divangahi

Robert Sladek

Thierry Muanza

Gerald Batist

Nicole Beauchemin

Francis Migneault

Mariela Segura

Imed Gallouzi

Mohammad-Ali Jenabian

Guillaume Bourque

Pnina Brodt

Emmanuelle Brochiero

Luc Desgroseillers

Sharon Walmsley

Mohammad-Ali Jenabian

Impact of ΔF508 CFTR mutation on diaphragm function during acute inflammation.