Carolyn Baglole, McGill University

Research

Aryl Hydrocarbon Receptor Chronic Obstructive Pulmonary Disease Cigarette Smoke Inflammation Fibroblast Lung Atherosclerosis E-Cigarette

Latest papers

Sex-specific alterations in pulmonary metabolic, xenobiotic and lipid signalling pathways after e-cigarette aerosol exposure during adolescence in mice.
BMJ open respiratory research · 2024 · senior author
Increased sensitivity to chemically induced colitis in mice harboring a DNA-binding deficient aryl hydrocarbon receptor.
Toxicological sciences : an official journal of the Society of Toxicology · 2023
Chronic aryl hydrocarbon receptor activity phenocopies smoking-induced skeletal muscle impairment.
Journal of cachexia, sarcopenia and muscle · 2022

All 3 publications

Latest funding

Does E-cigarette Use Enhance Lung Tumor Formation?
CIHR · 2025 · Co-investigator
$67,500
Exploring the cardiometabolic consequences of vaping
CIHR · 2025 · Supervisor
$120,000
Wildfire smoke inhibition of CFTR: mechanisms and mitigation
CIHR · 2024 · Co-investigator
$994,500

All 20 grants and awards

3 publications.

01

Sex-specific alterations in pulmonary metabolic, xenobiotic and lipid signalling pathways after e-cigarette aerosol exposure during adolescence in mice.

Paoli S, Eidelman DH, Mann KK, Baglole C

BMJ open respiratory research2024Senior author

DOI: 10.1136/bmjresp-2024-002423 PMID: 39299769

02

Increased sensitivity to chemically induced colitis in mice harboring a DNA-binding deficient aryl hydrocarbon receptor.

Alvik K, Shao P, Hutin D, Baglole C, Grant DM, Matthews J

Toxicological sciences : an official journal of the Society of Toxicology2023

DOI: 10.1093/toxsci/kfac132 PMID: 36519841

03

Chronic aryl hydrocarbon receptor activity phenocopies smoking-induced skeletal muscle impairment.

Thome T, Miguez K, Willms AJ, Burke SK, Chandran V, de Souza AR, Fitzgerald LF, Baglole C, Anagnostou ME, Bourbeau J, Jagoe RT, Morais JA, Goddard Y, Taivassalo T, Ryan TE, Hepple RT

Journal of cachexia, sarcopenia and muscle2022

DOI: 10.1002/jcsm.12826 PMID: 34725955

Does E-cigarette Use Enhance Lung Tumor Formation?

Co-investigatorCIHR2025CIHR-ICR / Cancer Research Society Partnership - Res. Gr. Cancer Prev.

Principal investigators: Mann, Koren K

Keywords: Cancer

$67,500

Exploring the cardiometabolic consequences of vaping

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Caruana, Vincenza

Keywords: Aav-Pcsk9; Atherosclerosis; Cardiovascular; Dyslipidemia; E-Cigarette; Hepatic Dysregulation; Metabolism; Omics; Sex-Specific; Vaping

$120,000

Wildfire smoke inhibition of CFTR: mechanisms and mitigation

Co-investigatorCIHR2024Project Grant

Principal investigators: Hanrahan, John W

Keywords: Acquired Cftr Deficiency; Cftr (Cystic Fibrosis Transmembrane Conductance Regulator); Copd Exacerbations; Redox Balance; Wildfire Smoke

$994,500

PPAR Signaling Disruption by Cannabis Products Impairs Respiratory Defense Mechanisms

SupervisorCIHR2024Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Arlen, Maddison T

Keywords: Cannabis; Cre-Lox Recombination; Exposure; Influenza; Innate Immunity; Lung Epithelium; Metabolomics; Ppar Signalling; Smoking; Vaping

$120,000

Development of Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

SupervisorCIHR2023CIHR-ICRH Travel Awards - General pool

Principal investigators: Gorgani, Roham

Keywords: Respiratory; Vaporized Cannabis Distillate Products

$1,500

Immunophenotypic di¿erences in the pulmonary response of BALB/c and C57BL/6 mice to e-cigarette aerosols

SupervisorCIHR2023CIHR-ICRH Travel Awards - General pool

Principal investigators: Paoli, Sofia

Keywords: E-Cigarette; Mice; Pulmonary Response

$1,500

Ahr Controls Pulmonary Inflammation from Cannabis Smoke

SupervisorCIHR2023CIHR-ICRH Travel Awards - General pool

Principal investigators: Wilson, Emily T

Keywords: Cannabis; Pulmonary Inflammation; Thc

$1,500

Decoding how the aryl hydrocarbon receptor (AhR) controls cigarette smoke-induced lung inflammation and development of chronic obstructive pulmonary disease (COPD)

Nominated PICIHR2023Project Grant

Principal investigators: Baglole, Carolyn

Keywords: Aryl Hydrocarbon Receptor; Chronic Obstructive Pulmonary Disease; Cigarette Smoke; Inflammation

$940,950

Smoke effects on cell function and role in COPD

Co-investigatorCIHR2023Project Grant - Priority Announcement: Health and Climate Change

Principal investigators: Hanrahan, John W

Keywords: Acquired Cftr Deficiency; Cftr (Cystic Fibrosis Transmembrane Conductance Regulator); Copd; Redox Balance; Smoke

Unagi: Computational approach driven repurposed drugs for idiopathic pulmonary fibrosis

Co-investigatorCIHR2021Project Grant

Principal investigators: Ding, Jun

Keywords: Cellular Dynamics; Cmap; Drug Repurposing; Graphical Models; Idiopathic Pulmonary Fibrosis; In-Silico; Machine Learning; Perturbation; Single Cell; Time-Series

$506,430

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Pharmacology and Toxicology

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Jason Matthews

Pharmacology and Toxicology

1 shared papers, latest 2023

Jean Bourbeau

Medicine

1 shared papers, latest 2022

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Aryl Hydrocarbon Receptor Dear Professor Baglole, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Sex-specific alterations in pulmonary metabolic, xenobiotic and lipid signalling pathways after e-cigarette aerosol exposure during adolescence in mice." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Decoding how the aryl hydrocarbon receptor (AhR) controls cigarette smoke-induced lung inflammation and development of chronic obstructive pulmonary disease (COPD)" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]