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Research
Latest papers
Enzyme Assays for Phosphoinositide Kinases and Phosphatases and Inhibitor Screens.
Methods in molecular biology (Clifton, N.J.) · 2026 · senior author
Identifying Trypanosoma cruzi Proteins Targeted by Chagas Disease Patient Antibodies Using Yeast Surface Display.
Methods in molecular biology (Clifton, N.J.) · 2026 · senior author
Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes.
Nature communications · 2025 · senior author
Latest funding
Therapeutic peptides for Chagas disease: a new approach to cardiovascular diseases
CIHR · 2022 · Nominated PI
- $768,825
Signalling and regulation of antigenic variation in trypanosomes
CIHR · 2020 · Nominated PI
- $12,500
Transcriptional control of telomeric expression sites and antigenic variation
NSERC · 2019 · Principal investigator
18 publications.
Enzyme Assays for Phosphoinositide Kinases and Phosphatases and Inhibitor Screens.
Gao M, Koirala M, Warren NB, Bede JC, Cestari I
Identifying Trypanosoma cruzi Proteins Targeted by Chagas Disease Patient Antibodies Using Yeast Surface Display.
Loock M, Cestari I
Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes.
Antunes LB, Isebe T, Kutova O, Cestari I
Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection.
Cruz-Saavedra L, Loock M, Antunes LB, Cestari I
Editorial: Cellular immune response and escape mechanisms of intracellular parasites.
Dutra PML, Rodrigues LS, Pinheiro RO, Pereira Manfro WF, Cestari I, Da-Silva SAG
Identifying Antigenic Switching by Clonal Cell Barcoding and Nanopore Sequencing in Trypanosoma brucei.
Touray AO, Sternlieb T, Isebe T, Cestari I
PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes.
Touray AO, Rajesh R, Isebe T, Sternlieb T, Loock M, Kutova O, Cestari I
High-Efficiency Transformation and Expression of Genomic Libraries in Yeast.
Loock M, Antunes LB, Heslop RT, De Lauri AA, Brito Lira A, Cestari I
Erratum: Update Notice: Efficient Generation of Genome-wide Libraries for Protein-ligand Screens Using Gibson Assembly.
Sternlieb T, Loock M, Gao M, Cestari I
Genome-Wide Libraries for Protozoan Pathogen Drug Target Screening Using Yeast Surface Display.
Heslop R, Gao M, Brito Lira A, Sternlieb T, Loock M, Sanghi SR, Cestari I
Therapeutic peptides for Chagas disease: a new approach to cardiovascular diseases
Principal investigators: Cestari, Igor; Alonso, Guillermo D; Qvit, Nir
Keywords: Biochemical Assays; Cardiovascular Disease; Chagas Disease; Drug Discovery; Molecular Parasitology; Peptidomimetic Inhibitors; Transgenic Parasites; Yeast Surface Display
Signalling and regulation of antigenic variation in trypanosomes
Principal investigators: Cestari, Igor
Keywords: Antigenic Variation; Chromatin Analysis; Genomics; Immune Evasion; Inositol Phosphates; Phosphoinositides; Protein Interactions; Proteomics; Signal Transduction; Transcription Control
Transcriptional control of telomeric expression sites and antigenic variation
Principal investigators: Cestari, Igor
Transcriptional control of telomeric expression sites and antigenic variation
Principal investigators: Cestari, Igor
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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