Reza Salavati, McGill University

Research

Biochemistry Bioinformatics Genome Annotation Proteomics

Latest papers

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists.
Wiley interdisciplinary reviews. RNA · 2026
Global Protein Interaction Network for Trypanosoma cruzi.
Journal of proteome research · 2026 · senior author
Beyond overlap in kinetoplastid interactomes.
Trends in parasitology · 2026 · senior author

All 48 publications

Latest funding

Regulation of editosome proteins in trypanosome differentiation
NSERC · 2024 · Principal investigator
$41,000
Enhanced Capability of Spinning Disk Confocal Microscope
NSERC · 2022 · Co-investigator
$150,000
Refrigerated microcentrifuge for radioisotope samples in life sciences research
NSERC · 2019 · Principal investigator
$16,500

All 14 grants and awards

48 publications.

01

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists.

McDermott SM, Lukeš J, Read LK, Salavati R, Schnaufer A, Zimmer SL, Carnes J, Ivens A, Poorinmohammad N, Savill NJ, Speijer D, Stuart K, Záhonová K, Borujeni PM, Chen Z, Goode C, Sharma SK, O'Hara L, Cruz-Reyes J

Wiley interdisciplinary reviews. RNA2026

DOI: 10.1002/wrna.70037 PMID: 41742325

02

Global Protein Interaction Network for Trypanosoma cruzi.

Azimi A, Gaudreault F, Sulea T, Salavati R

Journal of proteome research2026Senior author

DOI: 10.1021/acs.jproteome.5c00649 PMID: 41407521

03

Beyond overlap in kinetoplastid interactomes.

Azimi A, Salavati R

Trends in parasitology2026Senior author

DOI: 10.1016/j.pt.2026.02.007 PMID: 41820074

04

A global protein interaction network of Leishmania donovani.

Azimi A, Salavati R

International journal for parasitology2026Senior author

DOI: 10.1016/j.ijpara.2025.10.001 PMID: 41072706

05

Comparative performance of structural aligners in functional domain annotation.

Borujeni PM, Salavati R

Journal of structural biology2026Senior author

DOI: 10.1016/j.jsb.2026.108308 PMID: 41786230

06

Functional domain annotation by structural similarity.

Borujeni PM, Salavati R

NAR genomics and bioinformatics2024Senior author

DOI: 10.1093/nargab/lqae005 PMID: 38298181

07

Prioritization of Trypanosoma brucei editosome protein interactions interfaces at residue resolution through proteome-scale network analysis.

Poorinmohammad N, Salavati R

BMC molecular and cell biology2024Senior author

DOI: 10.1186/s12860-024-00499-4 PMID: 38279116

08

High-throughput screening of compounds targeting RNA editing in Trypanosoma brucei: Novel molecular scaffolds with broad trypanocidal effects.

Rostamighadi M, Kamelshahroudi A, Mehta V, Zeng FY, Pass I, Chung TDY, Salavati R

Biochemical pharmacology2024Senior author

DOI: 10.1016/j.bcp.2023.115937 PMID: 37995979

09

Revisiting the functional annotation of TriTryp using sequence similarity tools.

Borujeni PM, Salavati R

Heliyon2024Senior author

DOI: 10.1016/j.heliyon.2024.e39243 PMID: 39640808

10

Pilot-Scale Screening of Clinically Approved Drugs to Identify Uridine Insertion/Deletion RNA Editing Inhibitors in Trypanosoma brucei.

Rostamighadi M, Kamelshahroudi A, Pitsitikas V, Jacobson KA, Salavati R

ACS infectious diseases2024Senior author

DOI: 10.1021/acsinfecdis.4c00394 PMID: 39118542

Regulation of editosome proteins in trypanosome differentiation

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Salavati, Reza

Keywords: rna editing; protozoan parasites; gene regulation; multi-protein complex; protein-protein interaction; differentiation

$41,000

Enhanced Capability of Spinning Disk Confocal Microscope

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Geitmann, Anja

$150,000

Refrigerated microcentrifuge for radioisotope samples in life sciences research

Principal investigatorNSERC2019Research Tools and Instruments

Principal investigators: Salavati, Reza

$16,500

Annotation and discovery of essential pathways in trypanosomatid pathogens

Nominated PICIHR2019Project Grant

Principal investigators: Salavati, Reza

Keywords: Biochemistry; Bioinformatics; Genome Annotation; Proteomics

$715,275

BioConnect 2017

Principal investigatorNSERC2017Connect Grants Level 2

Principal investigators: Salavati, Reza

$3,000

Quantitative high content live cell imaging platform

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Rohrbach, Petra

$147,132

Scintillation Counter for Life Sciences Research

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Whyte, Lyle

$57,616

Developmental regulation of mitochondrial RNA editing in trypanosomes

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Salavati, Reza

$228,000

Identification of diagnostic markers for infectious agents

Principal investigatorNSERC2015Engage Grants Program

Principal investigators: Salavati, Reza

$25,000

Targeting the editosome in Trypanosoma brucei - from function to drug discovery

Nominated PICIHR2011Operating Grant

Principal investigators: Salavati, Reza

Keywords: Biochemistry; Chemical Screen; Drug Target Characterization; Enzyme Kinetics; Rna Processing

$296,235

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Institute of Parasitology
Human Genetics

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Hamed Shateri Najafabadi

Human Genetics

2 shared papers, latest 2012

Igor Cestari

Institute of Parasitology

1 shared papers, latest 2020

Tomi Pastinen

Human Genetics

1 shared papers, latest 2013

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2024

Subject: Prospective PhD student: Biochemistry Dear Professor Salavati, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Regulation of editosome proteins in trypanosome differentiation" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]