Petra Rohrbach, McGill University

Research

acidic digestive vacuole compartment biogenesis hemazoin formation live cell imaging Malaria membrane transporter pH regulation Plasmodium falciparum

Latest papers

A Reproducible Protocol for the Isolation of Malaria-Derived Extracellular Vesicles by Differential Centrifugation.
Methods and protocols · 2024 · senior author
Quantifying pH in Malaria Using pHluorin and Flow Cytometry.
Methods in molecular biology (Clifton, N.J.) · 2023 · senior author
A tail-specific protease is required for Legionella pneumophila intracellular multiplication.
Canadian journal of microbiology · 2022

All 19 publications

Latest funding

Tabletop Scanning Electron Microscope for the Study of Biomaterials
NSERC · 2024 · Co-investigator
$150,000
The malaria digestive vacuole: its role in parasite development
NSERC · 2020 · Principal investigator
$192,000
Quantitative high content live cell imaging platform
NSERC · 2016 · Principal investigator
$147,132

All 8 grants and awards

19 publications.

01

A Reproducible Protocol for the Isolation of Malaria-Derived Extracellular Vesicles by Differential Centrifugation.

Opadokun T, Rohrbach P

Methods and protocols2024Senior author

DOI: 10.3390/mps7060092 PMID: 39584985

02

Quantifying pH in Malaria Using pHluorin and Flow Cytometry.

Agyapong J, Rohrbach P

Methods in molecular biology (Clifton, N.J.)2023Senior author

DOI: 10.1007/978-1-0716-3052-5_13 PMID: 37142924

03

A tail-specific protease is required for Legionella pneumophila intracellular multiplication.

Saoud J, Mani T, Rohrbach P, Faucher SP

Canadian journal of microbiology2022

DOI: 10.1139/cjm-2022-0119 PMID: 36194898

04

Malaria Detection Accelerated: Combing a High-Throughput NanoZoomer Platform with a ParasiteMacro Algorithm.

Ashraf S, Khalid A, de Vos AL, Feng Y, Rohrbach P, Hasan T

Pathogens (Basel, Switzerland)2022

DOI: 10.3390/pathogens11101182 PMID: 36297240

05

Protein Profiling of Malaria-Derived Extracellular Vesicles Reveals Distinct Subtypes.

Opadokun T, Agyapong J, Rohrbach P

Membranes2022Senior author

DOI: 10.3390/membranes12040397 PMID: 35448366

06

PfMDR1 Transport Rates Assessed in Intact Isolated Plasmodium falciparum Digestive Vacuoles Reflect Functional Drug Resistance Relationship with pfmdr1 Mutations.

Simon N, Voigtländer C, Kappes B, Rohrbach P, Friedrich O

Pharmaceuticals (Basel, Switzerland)2022

DOI: 10.3390/ph15020202 PMID: 35215316

07

OPD (Online Plasmodium Diagnosis): An ALA-PpIX based functional assay to predict active malaria.

Ashraf S, Agyapong J, Rohrbach P, Hasan T

Photodiagnosis and photodynamic therapy2021

DOI: 10.1016/j.pdpdt.2021.102510 PMID: 34474169

08

Extracellular vesicles in malaria: an agglomeration of two decades of research.

Opadokun T, Rohrbach P

Malaria journal2021Senior author

DOI: 10.1186/s12936-021-03969-8 PMID: 34801056

09

Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP).

Mathew R, Wunderlich J, Thivierge K, Cwiklinski K, Dumont C, Tilley L, Rohrbach P, Dalton JP

Scientific reports2021

DOI: 10.1038/s41598-021-82499-4 PMID: 33536500

10

Genotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum.

Valenzuela G, Castro LE, Valencia-Zamora J, Vera-Arias CA, Rohrbach P, Sáenz FE

Malaria journal2019

DOI: 10.1186/s12936-019-3044-z PMID: 31822269

Tabletop Scanning Electron Microscope for the Study of Biomaterials

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Geitmann, Anja

Keywords: Biomaterials; Biopolymers; Energy dispersive x-ray spectroscopy (EDS); Food packaging; Malaria; Plant development; Scanning electron microscope; Scanning-transmission electron microscopy (STEM); Viral infection

$150,000

The malaria digestive vacuole: its role in parasite development

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Rohrbach, Petra

Keywords: malaria; plasmodium falciparum; acidic digestive vacuole; ph regulation; hemazoin formation; compartment biogenesis; solute transport; membrane transporter; live cell imaging; transcriptomics

$192,000

Quantitative high content live cell imaging platform

Principal investigatorNSERC2016Research Tools and Instruments

Principal investigators: Rohrbach, Petra

$147,132

The malaria digestive vacuole: elucidating its function in parasite physiology and development

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Rohrbach, Petra

$150,000

Next Gen Sequencing Platform for Environmental Sciences

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Whyte, Lyle

$125,635

Role of small regulatory RNAs expressed by the intracellular pathogen Legionella pneumophila.

Co-investigatorCIHR2015Operating Grant

Principal investigators: Faucher, Sébastien

Keywords: Legionella Pneumophila; Macrophages; Rna-Seq; Small Regulatory Rnas; Virulence Factors

$472,140

Environment and Detection System for Live Cell Imaging

Principal investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Rohrbach, Petra

$97,360

The multidrug resistance transporter (MDR1) of human malaria: elucidation of its critical function in malaria physiology and its contribution to the development of drug resistance

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Rohrbach, Petra

$155,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Elias Georges

Institute of Parasitology

1 shared papers, latest 2014

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: acidic digestive vacuole Dear Professor Rohrbach, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "A Reproducible Protocol for the Isolation of Malaria-Derived Extracellular Vesicles by Differential Centrifugation." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "The malaria digestive vacuole: its role in parasite development" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]