Faculty profile

Ralf Schirrmacher

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Ralf Schirrmacher

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
No publications since 2016.
Principal investigator on 7 research grants (4 CIHR, 3 NSERC), most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

In Vivo Imaging Positron Emission Tomography Tyrosine Kinase Receptor

Latest papers

Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1.
Cerebrovascular diseases (Basel, Switzerland) · 2016 · first author
Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors.
Molecular pharmaceutics · 2015
Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.
Chemical communications (Cambridge, England) · 2015 · senior author

All 26 publications

Latest funding

Non-invasive PET imaging of tropomyosin related kinase B/C receptor in humans
CIHR · 2019 · Principal investigator
$579,106
Novel hydrophilic Silicon-Fluoride-Acceptors (SiFAs) for in vivo Positron Emission Tomography (PET)
NSERC · 2013 · Principal investigator
$264,000
A gold-nanoparticle kit for the development of tailor-made radiodiagnostics and radio-therapeutics
NSERC · 2011 · Principal investigator
$411,798

All 10 grants and awards

26 publications.

Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1.

Schirrmacher R, Dea M, Heiss WD, Kostikov A, Funck T, Quessy S, Bedell B, Dancause N, Thiel A

Cerebrovascular diseases (Basel, Switzerland)2016First author

DOI: 10.1159/000442997 PMID: 26752046

Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors.

Tomaszowski KH, Schirrmacher R, Kaina B

Molecular pharmaceutics2015

DOI: 10.1021/acs.molpharmaceut.5b00341 PMID: 26379107

Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.

Zhu J, Li S, Wängler C, Wängler B, Lennox RB, Schirrmacher R

Chemical communications (Cambridge, England)2015Senior author

DOI: 10.1039/c5cc03623b PMID: 26145162

In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

Niedermoser S, Chin J, Wängler C, Kostikov A, Bernard-Gauthier V, Vogler N, Soucy JP, McEwan AJ, Schirrmacher R, Wängler B

Journal of nuclear medicine : official publication, Society of Nuclear Medicine2015

DOI: 10.2967/jnumed.114.149583 PMID: 25977461

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.

Bernard-Gauthier V, Aliaga A, Aliaga A, Boudjemeline M, Hopewell R, Kostikov A, Rosa-Neto P, Thiel A, Schirrmacher R

ACS chemical neuroscience2015Senior author

DOI: 10.1021/cn500193f PMID: 25350780

5-(4-((4-[(18)F]Fluorobenzyl)oxy)-3-methoxybenzyl)pyrimidine-2,4-diamine: a selective dual inhibitor for potential PET imaging of Trk/CSF-1R.

Bernard-Gauthier V, Schirrmacher R

Bioorganic & medicinal chemistry letters2014Senior author

DOI: 10.1016/j.bmcl.2014.09.014 PMID: 25257201

Rapid (18)F-labeling and loading of PEGylated gold nanoparticles for in vivo applications.

Zhu J, Chin J, Wängler C, Wängler B, Lennox RB, Schirrmacher R

Bioconjugate chemistry2014Senior author

DOI: 10.1021/bc5001593 PMID: 24807200

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

Wängler C, Chowdhury S, Höfner G, Djurova P, Purisima EO, Bartenstein P, Wängler B, Fricker G, Wanner KT, Schirrmacher R

Journal of medicinal chemistry2014Senior author

DOI: 10.1021/jm5004123 PMID: 24779610

¹⁸F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.

Bernard-Gauthier V, Wängler C, Schirrmacher E, Kostikov A, Jurkschat K, Wängler B, Schirrmacher R

BioMed research international2014Senior author

DOI: 10.1155/2014/454503 PMID: 25157357

Bimodal imaging probes for combined PET and OI: recent developments and future directions for hybrid agent development.

Seibold U, Wängler B, Schirrmacher R, Wängler C

BioMed research international2014

DOI: 10.1155/2014/153741 PMID: 24822177

Non-invasive PET imaging of tropomyosin related kinase B/C receptor in humans

Principal investigatorCIHR2019Project Grant

Principal investigators: Thiel, Alexander; Schirrmacher, Ralf

Keywords: In Vivo Imaging; Positron Emission Tomography; Tyrosine Kinase Receptor

$579,106

Novel hydrophilic Silicon-Fluoride-Acceptors (SiFAs) for in vivo Positron Emission Tomography (PET)

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Schirrmacher, Ralf

$264,000

A gold-nanoparticle kit for the development of tailor-made radiodiagnostics and radio-therapeutics

Principal investigatorNSERC2011Strategic Projects - Group

Principal investigators: Schirrmacher, Ralf

$411,798

CANADA RESEARCH CHAIRHOLDER/TITULAIRE DES CHAIRES DE RECHERCHE DU CANADA

Nominated PICIHR2011Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Schirrmacher, Ralf

Keywords: Chairs

$500,000

Imaging genotype-phenotype relationships in post-stroke recovery

Co-investigatorCIHR2011Operating Grant

Principal investigators: Thiel, Alexander

Keywords: Genetic Risk Factors; Mri; Pet; Stroke Recovery; Tms

$823,314

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Nominated PICIHR2009Operating Grant

Principal investigators: Schirrmacher, Ralf

Keywords: Diabetes; Fluorine-18; Pet Imaging; Radiochemistry; Radiolabeled Sur1 Ligands

$238,386

Prostate cancer: Somatic genetics and novel therapeutics

Co-investigatorCIHR2008Emerging Team Grant: From Genes to Proteins, Cells, Tissues and Patients - LOI

Principal investigators: Trifiro, Mark A; Corcos, Jacques; Purisima, Enrico O; Schirrmacher, Esther; Wang, Edwin

Keywords: Animal Models; Prostate Cancer; Protein Structure And Function; Somatic Genetics; Systems Biology; Therapeutics

CIHR Strategic Training Program in Chemical Biology

Co-investigatorCIHR2008Training Grant

Principal investigators: Thomas, David Y

Keywords: Asthma; Biochemistry; Bioinformatics; Biopharmaceutical; Chemical; Chemical Biology; Chemistry; Cystic Fibrosis; Genetics; Infectious Diseases; Pharmacology; Structural Biology

$1,538,350

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Nominated PICIHR2008Operating Grant - PA: Inst of Nutrition, Metabolism and Diabetes -Bridge Funding

Principal investigators: Schirrmacher, Ralf

Keywords: Diabetes; Fluorine-18; Pet Imaging; Radiochemistry; Radiolabeled Sur1 Ligands

$81,155

Targeted radiopharmaceutical delivery to the brain

Principal investigatorNSERC2008Discovery Grants Program - Individual

Principal investigators: Schirrmacher, Ralf

$126,150

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Ralf Schirrmacher

Research

Latest papers

Latest funding

Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1.

Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors.

Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.

In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.

5-(4-((4-[(18)F]Fluorobenzyl)oxy)-3-methoxybenzyl)pyrimidine-2,4-diamine: a selective dual inhibitor for potential PET imaging of Trk/CSF-1R.

Rapid (18)F-labeling and loading of PEGylated gold nanoparticles for in vivo applications.

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

¹⁸F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.

Bimodal imaging probes for combined PET and OI: recent developments and future directions for hybrid agent development.

Non-invasive PET imaging of tropomyosin related kinase B/C receptor in humans

Novel hydrophilic Silicon-Fluoride-Acceptors (SiFAs) for in vivo Positron Emission Tomography (PET)

A gold-nanoparticle kit for the development of tailor-made radiodiagnostics and radio-therapeutics

CANADA RESEARCH CHAIRHOLDER/TITULAIRE DES CHAIRES DE RECHERCHE DU CANADA

Imaging genotype-phenotype relationships in post-stroke recovery

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Prostate cancer: Somatic genetics and novel therapeutics

CIHR Strategic Training Program in Chemical Biology

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Targeted radiopharmaceutical delivery to the brain

Frequent collaborators

Alexander Thiel

Alexey Kostikov

Jean-Paul Soucy

Andrew Reader

Pedro Rosa-Neto

Alan Evans

Numa Dancause

Ralf Schirrmacher

Research

Latest papers

Latest funding

Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1.

Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors.

Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.

In Vivo Evaluation of &#xb9;&#x2078;F-SiFAlin-Modified TATE: A Potential Challenge for &#x2076;&#x2078;Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.

5-(4-((4-[(18)F]Fluorobenzyl)oxy)-3-methoxybenzyl)pyrimidine-2,4-diamine: a selective dual inhibitor for potential PET imaging of Trk/CSF-1R.

Rapid (18)F-labeling and loading of PEGylated gold nanoparticles for in vivo applications.

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

&#xb9;&#x2078;F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.

Bimodal imaging probes for combined PET and OI: recent developments and future directions for hybrid agent development.

Non-invasive PET imaging of tropomyosin related kinase B/C receptor in humans

Novel hydrophilic Silicon-Fluoride-Acceptors (SiFAs) for in vivo Positron Emission Tomography (PET)

A gold-nanoparticle kit for the development of tailor-made radiodiagnostics and radio-therapeutics

CANADA RESEARCH CHAIRHOLDER/TITULAIRE DES CHAIRES DE RECHERCHE DU CANADA

Imaging genotype-phenotype relationships in post-stroke recovery

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Prostate cancer: Somatic genetics and novel therapeutics

CIHR Strategic Training Program in Chemical Biology

Beta-cell imaging with 18F-labeled glibenclamide-glucose conjugates by positron emission tomography

Targeted radiopharmaceutical delivery to the brain

Frequent collaborators

Alexander Thiel

Alexey Kostikov

Jean-Paul Soucy

Andrew Reader

Pedro Rosa-Neto

Alan Evans

Numa Dancause

In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

¹⁸F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.