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Research
Latest papers
Size Matters: A Biophysical Perspective on Biomolecular Condensates in Bacteria.
Annual review of biophysics · 2026
Genome integrity relies on rapid recycling of DNA Pol III in bacteria.
Proceedings of the National Academy of Sciences of the United States of America · 2025 · senior author
The Rtf1/Prf1-dependent histone modification axis counteracts multi-drug resistance in fission yeast.
Life science alliance · 2024
Latest funding
- $135,074
Upgrades to fluorescence microscopes for quantitative live-cell imaging
NSERC · 2025 · Principal investigator
- $761,176
Elucidating the response to DNA damage at the replication fork
CIHR · 2021 · Nominated PI
- $192,000
Timing the bacterial replisome in live cells
NSERC · 2019 · Principal investigator
24 publications.
Size Matters: A Biophysical Perspective on Biomolecular Condensates in Bacteria.
Hodgins L, Parmar BS, Reyes-Lamothe R, Weber SC
Genome integrity relies on rapid recycling of DNA Pol III in bacteria.
Rascón Pérez JP, d'Acoz OD, Soubry N, Xu W, Singh Parmar B, Weber SC, Reyes-Lamothe R
The Rtf1/Prf1-dependent histone modification axis counteracts multi-drug resistance in fission yeast.
Chen JJ, Moy C, Pagé V, Monnin C, El-Hajj ZW, Avizonis DZ, Reyes-Lamothe R, Tanny JC
Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib to amikacin resistance.
d'Udekem d'Acoz O, Hue F, Ye T, Wang L, Leroux M, Rajngewerc L, Tran T, Phan K, Ramirez MS, Reisner W, Tolmasky ME, Reyes-Lamothe R
Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] to amikacin resistance.
d'Acoz OD, Hue F, Ye T, Wang L, Leroux M, Rajngewerc L, Tran T, Phan K, Ramirez MS, Reisner W, Tolmasky ME, Reyes-Lamothe R
RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size.
Swaffer MP, Marinov GK, Zheng H, Fuentes Valenzuela L, Tsui CY, Jones AW, Greenwood J, Kundaje A, Greenleaf WJ, Reyes-Lamothe R, Skotheim JM
Characterizing interaction of multiple nanocavity confined plasmids in presence of large DNA model nucleoid.
Liu Z, Christensen SM, Capaldi X, Hosseini SI, Zeng L, Zhang Y, Reyes-Lamothe R, Reisner W
Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity.
Liu Z, Capaldi X, Zeng L, Zhang Y, Reyes-Lamothe R, Reisner W
Dynamics of Proteins and Macromolecular Machines in Escherichia coli.
Leroux M, Soubry N, Reyes-Lamothe R
Bound2Learn: a machine learning approach for classification of DNA-bound proteins from single-molecule tracking experiments.
Kapadia N, El-Hajj ZW, Reyes-Lamothe R
Upgrades to fluorescence microscopes for quantitative live-cell imaging
Principal investigators: Reyes Lamothe, Rodrigo
Keywords: fluorescence microscopy; live-cell imaging; bacteria; yeast; chromosomes; single-molecule microscopy; liquid-liquid phase separation
Elucidating the response to DNA damage at the replication fork
Principal investigators: Reyes Lamothe, Rodrigo
Keywords: Budding Yeast; Dna Damage Response; Dna Repair; Dna Replication; Dna-Protein Binding Kinetics; Genome Integrity; Single-Molecule Microscopy
Timing the bacterial replisome in live cells
Principal investigators: ReyesLamothe, Rodrigo
Mechanisms and implications of fast turnover in the DNA replication machinery of bacteria
Principal investigators: Reyes Lamothe, Rodrigo
Keywords: Bacteria; Chromosome; Dna Replication; Genome Integrity; Live-Cell Fluorescence Microscopy; Single-Molecule Microscopy
Chromosome Biology
Principal investigators: Reyes Lamothe, Rodrigo
Chromosome Biology
Principal investigators: ReyesLamothe, Rodrigo
Chromosome Biology
Principal investigators: Reyes Lamothe, Rodrigo
Super-resolution imaging of ORC and MCM binding dynamics in live yeast cells
Principal investigators: Yu, Angela
Keywords: Characterization; Dna Replication; Firing; Live Cells; Origin; Replication; Spatiotemporal; Yeast
Bioengineering Facility for Confocal Rheology
Principal investigators: Ehrlicher, Allen
Shining light on the architecture and dynamics of the eukaryotic replisome
Principal investigators: Reyes Lamothe, Rodrigo
Keywords: Biochemistry; Chromosome; Dna Replication; Genome Integrity; Saccharomyces Cerevisiae; Single-Molecule Microscopy
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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