This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif.
Nucleic acids research · 2026
A guide RNA repeat checkpoint steers CRISPR-Cas9 catalysis.
bioRxiv : the preprint server for biology · 2025
A Generalizable Screening Platform for Developing Functional Aptasensors.
Analytical chemistry · 2025
Latest funding
- $105,000
Elucidating mRNA-Lipid Nanoparticle Formulation Efficacy using Single-Particle Fluorescence Imaging
CIHR · 2023 · Supervisor
- $50,000
Loading and release of RNA for COVID-19 vaccines: direct visualization of lipid nanoparticle delivery vehicles._x000d_ _x000d_ _x000d_ _x000d_
NSERC · 2020 · Principal investigator
- $350,000
Single-molecule manipulation and imaging platform
NSERC · 2018 · Principal investigator
7 publications.
CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif.
Chilamkurthy R, Sudhakar S, Pater AA, Bosmeny MS, Stabile F, Katolik A, Harikrishna S, El Azzouzi F, Turk R, Damha MJ, Leslie S, Korolev S, Pradeepkumar PI, Gagnon KT
A guide RNA repeat checkpoint steers CRISPR-Cas9 catalysis.
Chilamkurthy R, Sudhakar S, Pater AA, Bosmeny MS, Stabile F, Katolik A, Harikrishna S, Turk R, Damha MJ, Leslie S, Korolev S, Pradeepkumar PI, Gagnon KT
A Generalizable Screening Platform for Developing Functional Aptasensors.
Belleperche M, Liu J, Chen Y, Zhang C, Karimi K, Leslie S, McKeague M
Non-equilibrium structural dynamics of supercoiled DNA plasmids exhibits asymmetrical relaxation.
Shaheen C, Hastie C, Metera K, Scott S, Zhang Z, Chen S, Gu G, Weber L, Munsky B, Kouzine F, Levens D, Benham C, Leslie S
Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles.
Kamanzi A, Gu Y, Tahvildari R, Friedenberger Z, Zhu X, Berti R, Kurylowicz M, Witzigmann D, Kulkarni JA, Leung J, Andersson J, Dahlin A, Höök F, Sutton M, Cullis PR, Leslie S
Single-cell analysis for drug development using convex lens-induced confinement imaging.
Thiombane NK, Coutin N, Berard D, Tahvildari R, Leslie S, Nislow C
Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules.
Scott S, Shaheen C, McGuinness B, Metera K, Kouzine F, Levens D, Benham CJ, Leslie S
Elucidating mRNA-Lipid Nanoparticle Formulation Efficacy using Single-Particle Fluorescence Imaging
Principal investigators: Zhang, Yao
Keywords: Biophysics; Drug Delivery; Fluorescence; Imaging; Lipid Nanoparticle; Live Cell
Loading and release of RNA for COVID-19 vaccines: direct visualization of lipid nanoparticle delivery vehicles._x000d_ _x000d_ _x000d_ _x000d_
Principal investigators: Leslie, Sabrina
Single-molecule manipulation and imaging platform
Principal investigators: Leslie, Sabrina
Single-molecule visualization and manipulation of protein and DNA interactions and dynamics, on nanoscale dimensions
Principal investigators: Leslie, Sabrina
Single-molecule visualization and manipulation of protein and DNA interactions and dynamics, on nanoscale dimensions
Principal investigators: Leslie, Sabrina
Nanoscale toolset for formatiing and visualizing single molecules
Principal investigators: Leslie, Sabrina
Visualizing and Directing Dynamic DNA Nanostructure Assembly With Single-Molecule Resolution
Principal investigators: Leslie, Sabrina
Market assessment of ""molecular manipulation and nanoscopy platform""
Principal investigators: Leslie, Sabrina
Identify and quantitate biomarkers using nanopores fabricated by controlled breakdown
Principal investigators: TabardCossa, Vincent
Massively parallel linearization and chemical treatment of DNA molecules using tunable nanoscale confinement
Principal investigators: Leslie, Sabrina
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Physics
- Pharmacology and Therapeutics
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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