Svetlana Komarova

Research

Bone Osteoclast Aging Atp Calcium Signaling Exercise Injury Mechanical Forces

Latest papers

Assessing Dental Implant Success: A Systematic Review and Meta-Analysis of Primary Versus Secondary Implantation in Free Bone Flap Reconstruction for Malignant Tumors.
Head & neck · 2025
Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions.
The journal of pain · 2024
Teledentistry for improving access to, and quality of oral health care: A protocol for an overview of systematic reviews and meta-analyses.
PloS one · 2024

All 13 publications

Latest funding

NanoSynergy: Pioneering In-Situ SEM Nanomechanical Testing for Breakthroughs in Energy, Electronics, and Health
NSERC · 2025 · Co-investigator
$150,000
Development of a new accessible high-throughput, long-duration imaging technology for the life sciences.
CIHR · 2024 · Co-investigator
$300,000
Exploring complex cellular interactions: mathematical modeling of bone mineralization, turnover, and mechanobiology
NSERC · 2020 · Principal investigator
$198,000

All 12 grants and awards

13 publications.

01

Assessing Dental Implant Success: A Systematic Review and Meta-Analysis of Primary Versus Secondary Implantation in Free Bone Flap Reconstruction for Malignant Tumors.

Dugast S, Longis J, Anquetil M, Corre P, Komarova S, Bertin H

Head & neck2025

DOI: 10.1002/hed.28059 PMID: 39737519

02

Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions.

Zorina-Lichtenwalter K, Ase AR, Verma V, Parra AIM, Komarova S, Khadra A, Séguéla P, Diatchenko L

The journal of pain2024

DOI: 10.1016/j.jpain.2023.09.011 PMID: 37742908

03

Teledentistry for improving access to, and quality of oral health care: A protocol for an overview of systematic reviews and meta-analyses.

Kengne Talla P, Allison P, Bussières A, Giraudeau N, Komarova S, Basiren Q, Bergeron F, Emami E

PloS one2024

DOI: 10.1371/journal.pone.0288677 PMID: 38165889

04

Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis.

Bertin H, Moussa MS, Komarova S

Reviews in endocrine & metabolic disorders2023Senior author

DOI: 10.1007/s11154-023-09832-2 PMID: 37632645

05

Delivering a Home-Based Exercise Program to Youth With Osteogenesis Imperfecta: Protocol for a Comparative-Approach Study.

Powell G, Gagnon M, Komarova S, Rauch F, Veilleux LN

JMIR research protocols2023

DOI: 10.2196/40262 PMID: 37399052

06

Fibrillin-1 regulates white adipose tissue development, homeostasis, and function.

Muthu ML, Tiedemann K, Fradette J, Komarova S, Reinhardt DP

Matrix biology : journal of the International Society for Matrix Biology2022

DOI: 10.1016/j.matbio.2022.05.002 PMID: 35533973

07

Fibrillin-1-regulated miR-122 has a critical role in thoracic aortic aneurysm formation.

Zhang RM, Tiedemann K, Muthu ML, Dinesh NEH, Komarova S, Ramkhelawon B, Reinhardt DP

Cellular and molecular life sciences : CMLS2022

DOI: 10.1007/s00018-022-04337-8 PMID: 35606547

08

Editorial: Ectopic Mineralization of Tissues: Mechanisms, Risk Factors, Diseases, and Prevention.

Kempf H, Komarova S, Murshed M

Frontiers in cell and developmental biology2021

DOI: 10.3389/fcell.2021.759702 PMID: 34760893

09

Future directions for bone metastasis research – highlights from the 2015 bone and the Oncologist new updates conference (BONUS)

Fernandes R, Siegel P, Komarova S, Hilton J, Addison C, Ibrahim MFK, Werier J, Dennis K, Singh G, Amir E

Journal of Bone Oncology201610 citations

DOI: 10.1016/j.jbo.2016.02.004

10

A new class of bioactive glasses: calcium-magnesium sulfophosphates.

Bassett DC, Meszaros R, Orzol D, Woy M, Zhang YL, Tiedemann K, Wondraczek L, Komarova S, Barralet JE

Journal of biomedical materials research. Part A2014

DOI: 10.1002/jbm.a.34955 PMID: 24115563

NanoSynergy: Pioneering In-Situ SEM Nanomechanical Testing for Breakthroughs in Energy, Electronics, and Health

Co-investigatorNSERC2025Research Tools and Instruments

Principal investigators: Hamidinejad, Mahdi

Keywords: nanomechanics; nanomaterials; nanostructures; in situ microscopy; nanomechanical testing

$150,000

Development of a new accessible high-throughput, long-duration imaging technology for the life sciences.

Co-investigatorCIHR2024Cat Gr: Develop./validation of new biomedical techniques/technolo.- General Pool

Principal investigators: Bub, Gil

Keywords: Artificial Intelligence; Biological Disease Models; Biophotonics; Cardiac Cultures; Drug Screening; High-Throughput; Imaging Technology; Optics; Osteoclast Cultures

$300,000

Exploring complex cellular interactions: mathematical modeling of bone mineralization, turnover, and mechanobiology

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Komarova, Svetlana

$198,000

Role of extracellular ATP in bone adaptation to mechanical environment

Nominated PICIHR2019Project Grant

Principal investigators: Komarova, Svetlana V; Willie, Bettina M

Keywords: Aging; Atp; Bone; Calcium Signaling; Exercise; Injury; Mechanical Forces; Osteoblast; P2 Receptors; Repair

$573,750

Autosynthetics: Cranial Regeneration

Co-investigatorCIHR2018Project Grant

Principal investigators: Barralet, Jake E

Keywords: Bioceramics; Bone; Cranium; Skull; Tissue Engineering; Vascularization

$631,124

Osteocalcin-driven metabolic changes in osteogenesis imperfecta

Nominated PICIHR2016Project Grant

Principal investigators: Komarova, Svetlana V; Rauch, Frank

Keywords: Genetic Disorders; Glucose; Insulin; Metabolism; Osteocalcin; Osteoclast; Osteogenesis Imperfecta

$696,150

Exploring complex cellular interactions: mathematical modeling and experimental studies of bone turnover

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Komarova, Svetlana

$140,000

Osteoclast regulation by fibrillins: mechanisms and therapeutic implications

Nominated PICIHR2014Operating Grant

Principal investigators: Komarova, Svetlana V; Reinhardt, Dieter P

Keywords: Bone Resorption; Extracellular Matrix; Fibrillin-1; Low Bone Mass; Marfan Syndrome; Osteoclasts; Osteoporosis

$673,210

Regulation of osteoclast formation and function in bone microenvironment

Nominated PICIHR2013Operating Grant

Principal investigators: Komarova, Svetlana V

Keywords: Anemia; Arthritis; Bone; Cancer Metastases; Co-Stimulatory Receptors; Osteoclast

$536,484

CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA

Nominated PICIHR2010Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Komarova, Svetlana V

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Medicine
Surgery
Biochemistry, Microbiology and Immunology
Restorative Dentistry
Pathology & Molecular Medicine
Orthopedic Surgery
Clinical Epidemiology
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Mark Clemons

Clinical Epidemiology

1 shared papers, latest 2016

Elham Emami

Restorative Dentistry

1 shared papers, latest 2024

Peter Siegel

Experimental Medicine

1 shared papers, latest 2016

Joel Werier

Orthopedic Surgery

1 shared papers, latest 2016

Christina Addison

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2016

Eitan Amir

Department of Medicine

1 shared papers, latest 2016

John Hilton

Department of Medicine

1 shared papers, latest 2016

Gurmit Singh

Pathology & Molecular Medicine

1 shared papers, latest 2016

Faleh Tamimi

Faculty

1 shared papers, latest 2012

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: Bone Dear Professor Komarova, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Assessing Dental Implant Success: A Systematic Review and Meta-Analysis of Primary Versus Secondary Implantation in Free Bone Flap Reconstruction for Malignant Tumors." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Exploring complex cellular interactions: mathematical modeling of bone mineralization, turnover, and mechanobiology" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Svetlana Komarova

Research

Latest papers

Latest funding

Assessing Dental Implant Success: A Systematic Review and Meta-Analysis of Primary Versus Secondary Implantation in Free Bone Flap Reconstruction for Malignant Tumors.

Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions.

Teledentistry for improving access to, and quality of oral health care: A protocol for an overview of systematic reviews and meta-analyses.

Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis.

Delivering a Home-Based Exercise Program to Youth With Osteogenesis Imperfecta: Protocol for a Comparative-Approach Study.

Fibrillin-1 regulates white adipose tissue development, homeostasis, and function.

Fibrillin-1-regulated miR-122 has a critical role in thoracic aortic aneurysm formation.

Editorial: Ectopic Mineralization of Tissues: Mechanisms, Risk Factors, Diseases, and Prevention.

Future directions for bone metastasis research – highlights from the 2015 bone and the Oncologist new updates conference (BONUS)

A new class of bioactive glasses: calcium-magnesium sulfophosphates.

NanoSynergy: Pioneering In-Situ SEM Nanomechanical Testing for Breakthroughs in Energy, Electronics, and Health

Development of a new accessible high-throughput, long-duration imaging technology for the life sciences.

Exploring complex cellular interactions: mathematical modeling of bone mineralization, turnover, and mechanobiology

Role of extracellular ATP in bone adaptation to mechanical environment

Autosynthetics: Cranial Regeneration

Osteocalcin-driven metabolic changes in osteogenesis imperfecta

Exploring complex cellular interactions: mathematical modeling and experimental studies of bone turnover

Osteoclast regulation by fibrillins: mechanisms and therapeutic implications

Regulation of osteoclast formation and function in bone microenvironment

CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA

Frequent collaborators

Mark Clemons

Elham Emami

Peter Siegel

Frank Rauch

Luda Diatchenko

Julie Fradette

Paul Allison

Jake Barralet

Paul Allison

Joel Werier

Pascaline Kengne Talla

Elham Emami

Urban Emmenegger

Christina Addison

Eitan Amir

Louis-Nicolas Veilleux

John Hilton

Gurmit Singh

Monzur Murshed

Faleh Tamimi